| Compound ID |
Compound Name |
Compound Formula |
|
CP0068092
|
(3,4-Dihydroxy-5-nitro-phenyl)-p-tolyl-methanone
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|
C14H11NO5
|
1
|
| 1 |
IC50 < 1 nM
|
|
|
|
CP0387334
|
5-(2-benzylpyrrolidin-1-yl)sulfonylquinolin-8-ol
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|
C20H20N2O3S
|
1
|
| 1 |
IC50 = 1.995 nM
|
|
|
|
CP0427211
|
5-cyclopentylsulfonyl-7-fluoroquinolin-8-ol
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|
C14H14FNO3S
|
1
|
| 1 |
IC50 = 1.995 nM
|
|
|
|
CP0534905
|
5-[3-(4-fluorophenyl)pyrrolidin-1-yl]sulfonylquinolin-8-ol
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|
C19H17FN2O3S
|
1
|
| 1 |
IC50 = 3.162 nM
|
|
|
|
CP0159103
|
7-fluoro-5-pyrrolidin-1-ylsulfonylquinolin-8-ol
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|
C13H13FN2O3S
|
1
|
| 1 |
IC50 = 3.981 nM
|
|
|
|
CP0404794
|
7-fluoro-5-(4-fluorophenyl)sulfonylquinolin-8-ol
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|
C15H9F2NO3S
|
1
|
| 1 |
IC50 = 3.981 nM
|
|
|
|
CP0437962
|
2-[(2,6-dimethylphenyl)methyl]-7-hydroxy-3,4-dihydro-1H-pyrido[1,2-a]pyrazin-8-one
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|
C17H20N2O2
|
1
|
| 1 |
IC50 = 6.3 nM
|
|
|
|
CP0438323
|
7-fluoro-5-(4-methylphenyl)sulfonylquinolin-8-ol
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|
C16H12FNO3S
|
1
|
| 1 |
IC50 = 6.31 nM
|
|
|
|
CP0534904
|
5-cyclopentylsulfonylquinolin-8-ol
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|
C14H15NO3S
|
1
|
| 1 |
IC50 = 6.31 nM
|
|
|
|
CP0476687
|
5-pyrrolidin-1-ylsulfonylquinolin-8-ol
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|
C13H14N2O3S
|
1
|
| 1 |
IC50 = 7.943 nM
|
|
|
|
CP0519742
|
7-chloro-5-pyrrolidin-1-ylsulfonylquinolin-8-ol
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|
C13H13ClN2O3S
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0355617
|
2-[(2,4-dichlorophenyl)methyl]-7-hydroxy-3,4-dihydro-1H-pyrido[1,2-a]pyrazin-8-one
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|
C15H14Cl2N2O2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0437963
|
2-[(2,6-dichlorophenyl)methyl]-7-hydroxy-3,4-dihydro-1H-pyrido[1,2-a]pyrazin-8-one
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|
C15H14Cl2N2O2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0559353
|
2-[(2,4-dimethylphenyl)methyl]-7-hydroxy-3,4-dihydro-1H-pyrido[1,2-a]pyrazin-8-one
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|
C17H20N2O2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0474014
|
2-[(2-chloro-6-fluorophenyl)methyl]-7-hydroxy-3,4-dihydro-1H-pyrido[1,2-a]pyrazin-8-one
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|
C15H14ClFN2O2
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0080125
|
5-(4-methylphenyl)sulfonylquinolin-8-ol
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|
C16H13NO3S
|
1
|
| 1 |
IC50 = 19.95 nM
|
|
|
|
CP0483087
|
7-chloro-5-cyclopentylsulfonylquinolin-8-ol
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|
C14H14ClNO3S
|
1
|
| 1 |
IC50 = 19.95 nM
|
|
|
|
CP0484717
|
7-methyl-5-pyrrolidin-1-ylsulfonylquinolin-8-ol
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|
C14H16N2O3S
|
1
|
| 1 |
IC50 = 19.95 nM
|
|
|
|
CP0576302
|
2-[(2,6-difluorophenyl)methyl]-7-hydroxy-3,4-dihydro-1H-pyrido[1,2-a]pyrazin-8-one
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|
C15H14F2N2O2
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0437965
|
2-[(2-chlorophenyl)methyl]-7-hydroxy-3,4-dihydro-1H-pyrido[1,2-a]pyrazin-8-one
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|
C15H15ClN2O2
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0462435
|
2-[(2-chloro-4-fluorophenyl)methyl]-7-hydroxy-3,4-dihydro-1H-pyrido[1,2-a]pyrazin-8-one
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|
C15H14ClFN2O2
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0575401
|
2-[(2,3-dimethylphenyl)methyl]-7-hydroxy-3,4-dihydro-1H-pyrido[1,2-a]pyrazin-8-one
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|
C17H20N2O2
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0533949
|
7-hydroxy-2-[(2-methylphenyl)methyl]-3,4-dihydro-1H-pyrido[1,2-a]pyrazin-8-one
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|
C16H18N2O2
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0536340
|
2-[(2-fluorophenyl)methyl]-7-hydroxy-3,4-dihydro-1H-pyrido[1,2-a]pyrazin-8-one
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|
C15H15FN2O2
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0438319
|
5-ethylsulfonylquinolin-8-ol
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|
C11H11NO3S
|
1
|
| 1 |
IC50 = 50.12 nM
|
|
|
|
CP0533948
|
7-hydroxy-2-[[2-(trifluoromethyl)phenyl]methyl]-3,4-dihydro-1H-pyrido[1,2-a]pyrazin-8-one
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|
C16H15F3N2O2
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0437961
|
2-[(2,5-dimethylphenyl)methyl]-7-hydroxy-3,4-dihydro-1H-pyrido[1,2-a]pyrazin-8-one
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|
C17H20N2O2
|
1
|
| 1 |
IC50 = 63 nM
|
|
|
|
CP0521500
|
5-[4-(trifluoromethyl)phenyl]sulfonylquinolin-8-ol
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|
C16H10F3NO3S
|
1
|
| 1 |
IC50 = 63.1 nM
|
|
|
|
CP0438321
|
7-fluoro-5-[4-(trifluoromethyl)phenyl]sulfonylquinolin-8-ol
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|
C16H9F4NO3S
|
1
|
| 1 |
IC50 = 79.43 nM
|
|
|
|
CP0544595
|
2-[(7-hydroxy-8-oxo-3,4-dihydro-1H-pyrido[1,2-a]pyrazin-2-yl)methyl]benzonitrile
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|
C16H15N3O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0412358
|
7-chloro-5-(4-fluorophenyl)sulfonylquinolin-8-ol
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|
C15H9ClFNO3S
|
1
|
| 1 |
IC50 = 199.53 nM
|
|
|
|
CP0556289
|
2-benzyl-7-hydroxy-3,4-dihydro-1H-pyrido[1,2-a]pyrazin-8-one
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|
C15H16N2O2
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
|
CP0575400
|
7-hydroxy-2-[(2-methoxyphenyl)methyl]-3,4-dihydro-1H-pyrido[1,2-a]pyrazin-8-one
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|
C16H18N2O3
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
|
CP0513468
|
5-(4-methylphenyl)quinolin-8-ol
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|
C16H13NO
|
1
|
| 1 |
IC50 = 251.19 nM
|
|
|
|
CP0438326
|
7-chloro-5-(4-methylphenyl)sulfonylquinolin-8-ol
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|
C16H12ClNO3S
|
1
|
| 1 |
IC50 = 316.23 nM
|
|
|
|
CP0559824
|
7-hydroxy-2-[(4-methoxyphenyl)methyl]-3,4-dihydro-1H-pyrido[1,2-a]pyrazin-8-one
Show/Hide
|
C16H18N2O3
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0437960
|
7-hydroxy-2-[[4-(trifluoromethyl)phenyl]methyl]-3,4-dihydro-1H-pyrido[1,2-a]pyrazin-8-one
Show/Hide
|
C16H15F3N2O2
|
1
|
| 1 |
IC50 = 450 nM
|
|
|
|
CP0559351
|
2-(2-ethylbutyl)-7-hydroxy-3,4-dihydro-1H-pyrido[1,2-a]pyrazin-8-one
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|
C14H22N2O2
|
1
|
| 1 |
IC50 = 630 nM
|
|
|
|
CP0567266
|
7-bromo-5-(4-methylphenyl)sulfonylquinolin-8-ol
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|
C16H12BrNO3S
|
1
|
| 1 |
IC50 = 1258.93 nM
|
|
|
|
CP0068732
|
8-quinolinol
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|
C9H7NO
|
1
|
| 1 |
IC50 = 1584.89 nM
|
|
|
|
CP0437958
|
7-hydroxy-2-(2-methylpropyl)-3,4-dihydro-1H-pyrido[1,2-a]pyrazin-8-one
Show/Hide
|
C12H18N2O2
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0437959
|
4-[(7-hydroxy-8-oxo-3,4-dihydro-1H-pyrido[1,2-a]pyrazin-2-yl)methyl]benzonitrile
Show/Hide
|
C16H15N3O2
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
|
CP0559352
|
7-hydroxy-2-(2-phenylethyl)-3,4-dihydro-1H-pyrido[1,2-a]pyrazin-8-one
Show/Hide
|
C16H18N2O2
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
|
CP0550247
|
(8-hydroxyquinolin-5-yl)-(4-methylphenyl)methanone
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|
C17H13NO2
|
1
|
| 1 |
IC50 = 3981.07 nM
|
|
|
|
CP0576301
|
7-hydroxy-2-(pyridin-3-ylmethyl)-3,4-dihydro-1H-pyrido[1,2-a]pyrazin-8-one
Show/Hide
|
C14H15N3O2
|
1
|
| 1 |
IC50 = 6300 nM
|
|
|
|
CP0412357
|
8-methoxy-5-pyrrolidin-1-ylsulfonylquinoline
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|
C14H16N2O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0438325
|
5-cyclopentylsulfonyl-7-(trifluoromethyl)quinolin-8-ol
Show/Hide
|
C15H14F3NO3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0476688
|
5-(4-methylphenyl)sulfonyl-7-(trifluoromethyl)quinolin-8-ol
Show/Hide
|
C17H12F3NO3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0521499
|
(8-hydroxyquinolin-5-yl)-pyrrolidin-1-ylmethanone
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|
C14H14N2O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0474013
|
2-(4-fluorobenzoyl)-7-hydroxy-3,4-dihydro-1H-pyrido[1,2-a]pyrazin-8-one
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|
C15H13FN2O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0563603
|
7-hydroxy-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-8-one
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|
C8H10N2O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0563986
|
2-(benzenesulfonyl)-7-hydroxy-3,4-dihydro-1H-pyrido[1,2-a]pyrazin-8-one
Show/Hide
|
C14H14N2O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
