Brief Information of the Compound and Protein
Compound Name
2-[(2,6-dimethylphenyl)methyl]-7-hydroxy-3,4-dihydro-1H-pyrido[1,2-a]pyrazin-8-one
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PubChem ID
CID: 129165493
Canonical SMILES
Cc1cccc(C)c1CN1CCn2cc(O)c(=O)cc2C1
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Compound Formula C17H20N2O2
Compound Structure
Protein Name
Catechol O-methyltransferase
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P21964
Gene Name
COMT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 6.3 nM
   TI
   LI
   LO
   TS
CL000154 HEK293-EBNA1-6E Homo sapiens (Human)  1
1
IC50 > 5000 nM
   TI
   LI
   LO
   TS