General Information of the Compound
Compound ID
CP0068732
Compound Name
8-quinolinol
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Synonyms
1-Azanaphthalene-8-ol
148-24-3
8-Chinolinol
8-Chinolinol [Czech]
8-HYDROXYQUINOLINE
8-Hydroxy-chinolin
8-Hydroxychinolin
8-OQ
8-Oxychinolin
8-Oxyquinoline
8-Quinol
8-quinolinol
Bioquin
Caswell No. 719
Fennosan
Fennosan H 30
Fennosan HF-15
Hydroxybenzopyridine
NCI-C55298
NSC 2039
NSC 615011
OXYQUINOLINE
Oxin
Oxine
Oxoquinoline
Oxybenzopyridine
Oxychinolin
Oxyquinoline
Oxyquinoline [USAN]
Phenopyridine
Quinoline, 8-hydroxy-
Quinophenol
Tumex
UNII-5UTX5635HP
Usaf ek-794
o-Oxychinolin
o-Oxychinolin [German]
quinolin-8-ol
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Structure
Formula
C9H7NO
Molecular Weight
145.161
Canonical SMILES
Oc1cccc2cccnc12
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InChI
InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H
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InChIKey
MCJGNVYPOGVAJF-UHFFFAOYSA-N
CAS
148-24-3
24804-14-6
123574-67-4
Physicochemical Property
logP
1.9404
Rotatable Bonds
0
Heavy Atom Count
11
Polar Areas
33.12
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
2
Complexity
11

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 1923
SID: 15170833
ChEMBL ID
CHEMBL310555
DrugBank ID
DB11145
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03627, Catechol O-methyltransferase
 Protein Info 
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1584.89 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3162.28 nM
Protein ID: PT00973, Methionine aminopeptidase 2
 Protein Info 
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 5600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2030 nM
Clinical Information about the Compound
Drug 1 ( OXYQUINOLINE )
Drug Name OXYQUINOLINE
Target(s)
Methionine aminopeptidase 2 (METAP2)
 Target Info 
Inhibitor