Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-[3-(4-fluorophenyl)pyrrolidin-1-yl]sulfonylquinolin-8-ol
    Show/Hide
 PubChem ID
CID: 122442007
Canonical SMILES
Oc1ccc(c2cccnc12)S(=O)(=O)N1CCC(C1)c1ccc(F)cc1
    Show/Hide
Compound Formula C19H17FN2O3S
Compound Structure
Protein Name
 Protein Info 
Catechol O-methyltransferase
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P21964
Gene Name
COMT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 3.162 nM
   TI
   LI
   LO
   TS