Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT03566 , Solute carrier organic anion transporter family member 1B1
Gene Name SLCO1B1
Organism Homo sapiens, Human
Protein Classification Transporter
Uniprot ID Q9Y6L6
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT03566
 
Compound ID Compound Name Compound Formula
CP0964645
(2S,5S,8S,14S,32S,35R,38S,46E,50S,54S)-54-[(5-fluoro-1H-indol-3-yl)methyl]-5-[(1R)-1-methoxyethyl]-8-[(4-methoxyphenyl)methyl]-14,32,35-trimethyl-49-oxa-19,27-dithia-1,4,7,10,16,31,34,37,55-nonazahexacyclo[36.14.4.121,25.140,44.02,50.010,14]octapentaconta-21,23,25(58),40,42,44(57),46-heptaene-3,6,9,15,30,33,36,53,56-nonone
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C69H85FN10O12S2
 1
1
EC50 = 130 nM
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CP0577981
(1S,9E,13S,17S,20S,23S,29S,55S,60R,63S)-63-(aminomethyl)-50-fluoro-20-[(1R)-1-hydroxyethyl]-23-[(4-methoxyphenyl)methyl]-29,60-dimethyl-12-oxa-34,68-dithia-16,19,22,25,31,41,42,43,46,56,58,61,64-tridecazadecacyclo[36.19.12.13,7.116,55.136,40.141,44.146,53.013,17.025,29.047,52]tetraheptaconta-3,5,7(74),9,36(73),37,39,42,44(72),47(52),48,50,53(71)-tridecaene-18,21,24,30,57,59,62,65,70-nonone
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C71H85FN14O12S2
 1
1
EC50 = 600 nM
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CP0543806
2-[2-[3-[[(1S,9E,13S,17S,20S,23S,29S,55S,60R,63S)-50-fluoro-20-[(1R)-1-hydroxyethyl]-23-[(4-methoxyphenyl)methyl]-29,63-dimethyl-18,21,24,30,57,59,62,65,70-nonaoxo-12-oxa-34,68-dithia-16,19,22,25,31,41,42,43,46,56,58,61,64-tridecazadecacyclo[36.19.12.13,7.116,55.136,40.141,44.146,53.013,17.025,29.047,52]tetraheptaconta-3,5,7(74),9,36(73),37,39,42,44(72),47(52),48,50,53(71)-tridecaen-60-yl]methylamino]-3-oxopropoxy]ethoxy]ethyl-trimethylazanium
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C81H105FN15O15S2+
 1
1
EC50 = 2500 nM
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CP0573928
3-[2-(2-aminoethoxy)ethoxy]-N-[[(1S,9E,13S,17S,20S,23S,29S,55S,60R,63S)-50-fluoro-20-[(1R)-1-hydroxyethyl]-23-[(4-methoxyphenyl)methyl]-29,60-dimethyl-18,21,24,30,57,59,62,65,70-nonaoxo-12-oxa-34,68-dithia-16,19,22,25,31,41,42,43,46,56,58,61,64-tridecazadecacyclo[36.19.12.13,7.116,55.136,40.141,44.146,53.013,17.025,29.047,52]tetraheptaconta-3,5,7(74),9,36(73),37,39,42,44(72),47(52),48,50,53(71)-tridecaen-63-yl]methyl]propanamide
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C78H98FN15O15S2
 1
1
EC50 = 6000 nM
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CP0354520
2-[2-[3-[[(1S,9E,13S,17S,20S,23S,29S,55S,60R,63S)-50-fluoro-20-[(1R)-1-hydroxyethyl]-23-[(4-methoxyphenyl)methyl]-29,60-dimethyl-18,21,24,30,57,59,62,65,70-nonaoxo-12-oxa-34,68-dithia-16,19,22,25,31,41,42,43,46,56,58,61,64-tridecazadecacyclo[36.19.12.13,7.116,55.136,40.141,44.146,53.013,17.025,29.047,52]tetraheptaconta-3,5,7(74),9,36(73),37,39,42,44(72),47(52),48,50,53(71)-tridecaen-63-yl]methylamino]-3-oxopropoxy]ethoxy]ethyl-trimethylazanium
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C81H105FN15O15S2+
 1
1
EC50 > 22000 nM
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CP0741284
bromosulphophthalein
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C20H8Br4Na2O10S2
 2
1
IC50 = 50 nM
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2
Km = 140 nM
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CP0053690
(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-25,30-diethyl-33-((1R,2R)-1-hydroxy-2-methylhex-4-enyl)-6,9,18-triisobutyl-3,21,24-triisopropyl-1,4,7,10,12,15,19,27,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone
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C63H113N11O12
 1
1
IC50 = 180 nM
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CP0383317
CB-01-11
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C37H47NO12
 1
1
IC50 = 230 nM
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CP0071702
BA-41166E
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C43H58N4O12
 3
1
IC50 = 300 nM
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2
IC50 = 2200 nM
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3
IC50 = 2300 nM
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CP0071076
(3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid
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C33H35FN2O5
 3
1
IC50 = 600 nM
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2
IC50 = 800 nM
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3
IC50 = 1600 nM
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CP0036175
1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[(2S)-3-methyl-2-{[methyl({[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl})carbamoyl]amino}butanamido]-1,6-diphenylhexan-2-yl]carbamate
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C37H48N6O5S2
 3
1
IC50 = 700 nM
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2
IC50 = 1000 nM
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3
IC50 = 5000 nM
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CP0036222
(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(1R,2R,4E)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-bis(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecone
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C62H111N11O12
 3
1
IC50 = 700 nM
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2
IC50 = 1200 nM
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3
Ki = 200 nM
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CP0906809
Atorvastatin acid
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C66H70F2N4O10
 1
1
IC50 = 870 nM
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CP0525905
Antamanide
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C64H78N10O10
 1
1
IC50 = 1000 nM
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CP0000815
Rapamycin C-7, analog 4
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C51H79NO13
 1
1
IC50 = 1100 nM
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CP0281104
(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-24-[(2S)-1-[4-(2-methoxyethyl)piperazin-1-yl]propan-2-yl]-1,4,7,10,12,15,19,25,27,28-decamethyl-6,9,18-tris(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
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C69H125N13O13
 1
1
IC50 = 1200 nM
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CP0002800
1-((p-(2-(5-chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexylurea
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C23H28ClN3O5S
 3
1
IC50 = 1400 nM
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2
IC50 = 2200 nM
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3
IC50 = 21000 nM
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CP0098465
2-methyl-N-[(2-methylpropan-2-yl)oxy]-4-[[(1R,2R)-2-[4-(5-methyl-1H-pyrazol-3-yl)benzoyl]cyclohexanecarbonyl]amino]pyrazole-3-carboxamide
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C27H34N6O4
 1
1
IC50 = 1400 nM
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CP0063832
(1R,2R)-2-[4-(5-methyl-1H-pyrazol-3-yl)benzoyl]-N-(4-oxo-6,7-dihydro-5H-pyrazolo[1,5-a]pyrazin-3-yl)cyclohexane-1-carboxamide
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C24H26N6O3
 1
1
IC50 = 2300 nM
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CP0098466
(1R,2R)-2-[4-(5-methyl-1H-pyrazol-3-yl)benzoyl]-N-(1-methyl-5-sulfamoylpyrazol-4-yl)cyclohexane-1-carboxamide
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C22H26N6O4S
 1
1
IC50 = 2500 nM
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CP0515547
5-(4-Fluoro-phenyl)-1-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide
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C33H33FN2O4
 1
1
IC50 = 2600 nM
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CP0415966
(3R,5R)-7-[(1S,2S,6R,8S,8aR)-8-[(2,2-dimethylbutanoyl)oxy]-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid
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C25H40O6
 1
1
IC50 = 3600 nM
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CP0666814
FK-506
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C44H69NO12
 1
1
IC50 = 3700 nM
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CP0415967
MEVINOLINIC ACID
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C24H38O6
 1
1
IC50 = 4000 nM
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CP0050782
(1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate
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C25H38O5
 4
1
IC50 = 4400 nM
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2
IC50 = 6000 nM
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3
IC50 = 9700 nM
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4
IC50 = 11000 nM
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CP0014077
2,2-Dimethyl-5-(2,5-dimethylphenoxy)valeriansaeure
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C15H22O3
 2
1
IC50 = 11000 nM
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2
IC50 = 38000 nM
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CP0005348
LOVASTATIN
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C24H36O5
 1
1
IC50 = 28000 nM
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CP0036382
CAS_52-53-9
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C27H38N2O4
 3
1
IC50 = 32000 nM
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2
IC50 = 64000 nM
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3
Ki = 52000 nM
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CP0423672
(3S,6S)-6-[3-[2-[[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxopyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl]methyl]-5-[(Z)-(3-ethenyl-4-methyl-5-oxopyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoyloxy]-3,4,5-trihydroxyoxane-2-carboxylic acid
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C39H44N4O12
 1
1
Km = 100 nM
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CP0847448
Bilirubin bisglucuronide
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C45H52N4O18
 1
1
Km = 280 nM
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CP0256501
17beta-Estradiol-17-(beta-D-glucuronide)
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C24H32O8
 1
1
Km = 3600 nM
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CP0376684
CAS_147511-69-1
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C25H24FNO4
 1
1
Km = 4800 nM
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CP0127632
ESTRONE
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C18H22O5S
 1
1
Km = 12500 nM
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CP0253768
[(3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-oxo-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-yl] hydrogen sulfate
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C19H28O5S
 1
1
Km = 21500 nM
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CP0848733
Phalloidin
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C34H46N8O11S
 1
1
Km = 39000 nM
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