General Information of the Compound
| Compound ID |
CP0005348
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| Compound Name |
LOVASTATIN
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| Synonyms |
Altocor
2beta,6alpha-Dimethyl-8alpha-(2-methyl-1-oxobutoxy)-mevinic acid lactone
6 Methylcompactin
6 alpha-Methylcompactin
6-Methylcompactin
6-alpha-Methylcompactin
6alpha-Methylcompactin
75330-75-5
Advicor (TN)
Altocor
Altocor (TN)
Altoprev
Altoprev (TN)
Artein
Aspirin/lisinopril/ lovastatin fixed-dose combination
Belvas
Cholestra
Closterol
Colevix
Hipolip
Hipovastin
L-154803
Lestatin
Lipdip
Lipivas
Lipofren
Liposcler
Lovalip
Lovalord
Lovastatin
Lovastatin & Primycin
Lovastatin (USP/INN)
Lovastatin [USAN:BAN:INN]
Lovastatin, (1 alpha(S*))-Isomer
Lovastatin, 1 alpha-Isomer (without R*/S* notation)
Lovastatina
Lovastatina [Spanish]
Lovastatine
Lovastatine [French]
Lovastatinum
Lovastatinum [Latin]
Lovasterol
Lovastin
Lozutin
MK 803
MK-803
MK803
ML-530B
MSD 803
Mevacor
Mevacor (TN)
Mevinacor
Mevinolin
Mevinolin from Aspergillus sp
Mevlor
Monacolin K
Monakolin K
Nergadan
Paschol
Rextat
Rodatin
Rovacor
Sivlor
Sivlor;Taucor
Statosan (TN)
Taucor
Tecnolip
Teroltrat
UNII-9LHU78OQFD
lovastatin
mevinolin
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| Structure |
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| Formula |
C24H36O5
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| Molecular Weight |
404.547
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| Canonical SMILES |
CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12
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| InChI |
InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19+,20-,21-,23-/m0/s1
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| InChIKey |
PCZOHLXUXFIOCF-BXMDZJJMSA-N
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| CAS |
74133-25-8
81739-26-6
75330-75-5
71949-96-7
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02011, 3-hydroxy-3-methylglutaryl-coenzyme A reductase
Protein ID: PT01546, ATP-dependent translocase ABCB1
Protein ID: PT04542, Bile salt export pump
Protein ID: PT03788, Intercellular adhesion molecule 1
Protein ID: PT03566, Solute carrier organic anion transporter family member 1B1
Clinical Information about the Compound