Brief Information of the Compound and Protein
Compound Name
 Compound Info 
LOVASTATIN
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 PubChem ID
CID: 53232
SID: 14879393
Canonical SMILES
CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12
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Compound Formula C24H36O5
Compound Structure
Protein Name
 Protein Info 
3-hydroxy-3-methylglutaryl-coenzyme A reductase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P04035
Gene Name
HMGCR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 29.5 nM
   TI
   LI
   LO
   TS
2
IC50 = 19800 nM
   TI
   LI
   LO
   TS
CL000063 Hep-G2
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 37 nM
   TI
   LI
   LO
   TS
2
IC50 = 50 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2 nM
2 IC50 = 2.2 nM
3 IC50 = 20 nM
4 IC50 = 29.5 nM
5 IC50 = 20100 nM
6 Ki = 0.6 nM