Brief Information of the Compound and Protein
Compound Name
(3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid
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PubChem ID
CID: 60823
SID: 14910832
Canonical SMILES
CC(C)c1c(C(=O)Nc2ccccc2)c(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC(O)=O)-c1ccccc1
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Compound Formula C33H35FN2O5
Compound Structure
Protein Name
Solute carrier organic anion transporter family member 1B1
Protein Classification
Transporter
>
Electrochemical transporter
>
SLC superfamily of solute carriers
>
SLC21/SLCO family of organic anion transporting polypeptides
Uniprot ID
Q9Y6L6
Gene Name
SLCO1B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000088 Flp-In-293 Homo sapiens (Human)  1
1
Km = 770 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  3
1
IC50 = 600 nM
   TI
   LI
   LO
   TS
2
IC50 = 800 nM
   TI
   LI
   LO
   TS
3
IC50 = 1600 nM
   TI
   LI
   LO
   TS