Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
 Cell Line Info 
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT02189 , Protein arginine N-methyltransferase 3
 Protein Info 
Gene Name PRMT3
Organism Homo sapiens, Human
Protein Classification Epigenetic regulator
Uniprot ID O60678
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006
 Cell Line Info 
 Protein ID: PT02189
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0127979
 Compound Info 
1-isoquinolin-6-yl-3-(2-oxo-2-pyrrolidin-1-ylethyl)urea
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C16H18N4O2
  3
1
EC50 = 1800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 91 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
3
IC50 = 225 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0231947
 Compound Info 
1-(7-fluoroisoquinolin-6-yl)-3-(2-oxo-2-pyrrolidin-1-ylethyl)urea
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C16H17FN4O2
  2
1
EC50 = 2700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 134 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0181806
 Compound Info 
1-isoquinolin-6-yl-3-[2-oxo-2-(3,3,4,4-tetrafluoropyrrolidin-1-yl)ethyl]urea
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C16H14F4N4O2
  2
1
EC50 = 3100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 240 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0181805
 Compound Info 
1-(7-methylisoquinolin-6-yl)-3-(2-oxo-2-pyrrolidin-1-ylethyl)urea
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C17H20N4O2
  1
1
EC50 = 5200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0462227
 Compound Info 
1-[2-(2,5-dimethylpyrrolidin-1-yl)-2-oxoethyl]-3-isoquinolin-6-ylurea
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C18H22N4O2
  1
1
IC50 = 134 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS