Brief Information of the Compound and Protein
Compound Name
1-[2-(2,5-dimethylpyrrolidin-1-yl)-2-oxoethyl]-3-isoquinolin-6-ylurea
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PubChem ID
CID: 137638943
Canonical SMILES
CC1CCC(C)N1C(=O)CNC(=O)Nc1ccc2cnccc2c1
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Compound Formula C18H22N4O2
Compound Structure
Protein Name
Protein arginine N-methyltransferase 3
Protein Classification
Epigenetic regulator
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Writer
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Protein methyltransferase
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Protein arginine methyltransferase
Uniprot ID
O60678
Gene Name
PRMT3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 134 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 22 nM