| Compound ID |
Compound Name |
Compound Formula |
|
CP0866395
|
7-((1R,2S,3R)-3-hydroxy-5-oxo-2-p-tolylcyclopentyl)heptanoic acid
Show/Hide
|
C19H26O4
|
1
|
| 1 |
EC50 = 94 nM
|
|
|
|
CP0938030
|
7-((1R,2S,3R,5R)-5-chloro-2-(2,3-dihydro-1H-inden-5-yl)-3-hydroxycyclopentyl)heptanoic acid
Show/Hide
|
C21H29ClO3
|
1
|
| 1 |
EC50 = 200 nM
|
|
|
|
CP0863771
|
methyl 7-((1R,2S,3R,5R)-5-chloro-2-(2,3-dihydro-1H-inden-5-yl)-3-hydroxycyclopentyl)heptanoate
Show/Hide
|
C22H31ClO3
|
1
|
| 1 |
EC50 = 506 nM
|
|
|
|
CP0866254
|
7-((1R,2S,3R,5R)-2-(4-tert-butylphenyl)-5-chloro-3-hydroxycyclopentyl)hept-5-enoic acid
Show/Hide
|
C22H31ClO3
|
1
|
| 1 |
EC50 = 1269 nM
|
|
|
|
CP0852857
|
7-((1R,2S,3R,5R)-5-chloro-3-hydroxy-2-(1-hydroxy-2,3-dihydro-1H-inden-5-yl)cyclopentyl)heptanoic acid
Show/Hide
|
C21H29ClO4
|
1
|
| 1 |
EC50 = 2993 nM
|
|
|
|
CP0924067
|
7-((1R,2S,3R)-2-(4-tert-butylphenyl)-3-hydroxy-5-oxocyclopentyl)heptanoic acid
Show/Hide
|
C22H32O4
|
1
|
| 1 |
EC50 = 4273 nM
|
|
|
|
CP0847242
|
5-[(R)-1-(4-tert-Butyl-phenyl)-5-oxo-pyrrolidin-2-ylmethoxymethyl]-thiophene-2-carboxylic acid
Show/Hide
|
C21H25NO4S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0852835
|
7-((1R,2S,3R,5R)-5-chloro-3-hydroxy-2-(4-(1-hydroxycyclobutyl)phenyl)cyclopentyl)hept-5-enoic acid
Show/Hide
|
C22H29ClO4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0856829
|
methyl 7-((1R,2S)-2-(3-((R)-hydroxy(1-propylcyclobutyl)methyl)phenyl)-5-oxocyclopentyl)hept-5-enoate
Show/Hide
|
C27H38O4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0863084
|
methyl 7-((1R,2S,3R,5R)-5-chloro-3-hydroxy-2-(3-(hydroxy(1-propylcyclobutyl)methyl)phenyl)cyclopentyl)hept-5-enoate
Show/Hide
|
C27H39ClO4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0863767
|
7-((1R,2S,3R)-3-hydroxy-2-(1-hydroxy-2,3-dihydro-1H-inden-5-yl)-5-oxocyclopentyl)heptanoic acid
Show/Hide
|
C21H28O5
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0866430
|
methyl 7-((1R,2S,3R)-2-(4-tert-butylphenyl)-3-hydroxy-5-oxocyclopentyl)hept-5-enoate
Show/Hide
|
C23H32O4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0866431
|
methyl 7-((1R,2S,3R)-2-(4-tert-butylphenyl)-3-hydroxy-5-oxocyclopentyl)heptanoate
Show/Hide
|
C23H34O4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0866433
|
7-((1R,2S,3R,5R)-2-(4-tert-butylphenyl)-5-chloro-3-hydroxycyclopentyl)heptanoic acid
Show/Hide
|
C22H33ClO3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0869429
|
7-((1R,2S,3R,5R)-5-chloro-3-hydroxy-2-(3-(hydroxy(1-propylcyclobutyl)methyl)phenyl)cyclopentyl)hept-5-enoic acid
Show/Hide
|
C26H37ClO4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0870436
|
methyl 7-((1R,2S,3R,5R)-5-chloro-3-hydroxy-2-(4-(1-hydroxycyclobutyl)phenyl)cyclopentyl)heptanoate
Show/Hide
|
C23H33ClO4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0882892
|
methyl 7-((1R,2S,3R)-2-(2,3-dihydro-1H-inden-5-yl)-3-hydroxy-5-oxocyclopentyl)heptanoate
Show/Hide
|
C22H30O4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0882894
|
7-((1R,2S)-2-(4-(cyclohexyl(hydroxy)methyl)phenyl)-5-oxocyclopentyl)heptanoic acid
Show/Hide
|
C25H36O4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0888294
|
methyl 7-((1R,2S,3R)-3-hydroxy-2-(3-(hydroxy(1-propylcyclobutyl)methyl)phenyl)-5-oxocyclopentyl)hept-5-enoate
Show/Hide
|
C27H38O5
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0888316
|
methyl 7-((1R,2S)-2-(4-(cyclohexyl(hydroxy)methyl)phenyl)-5-oxocyclopentyl)heptanoate
Show/Hide
|
C26H38O4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0900745
|
7-((1R,2S,3R,5R)-5-chloro-3-hydroxy-2-(4-(1-hydroxycyclobutyl)phenyl)cyclopentyl)heptanoic acid
Show/Hide
|
C22H31ClO4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0909260
|
methyl 7-((1R,2S,3R,5R)-5-chloro-3-hydroxy-2-(1-hydroxy-2,3-dihydro-1H-inden-5-yl)cyclopentyl)heptanoate
Show/Hide
|
C22H31ClO4
|
1
|
| 1 |
EC50 = 17525 nM
|
|
|
|
CP0514365
|
1-[2-(4-methylanilino)-5-nitrophenyl]sulfonyl-3-pentylurea
Show/Hide
|
C19H24N4O5S
|
2
|
| 1 |
IC50 = 13.56 nM
|
|
|
| 2 |
IC50 = 50.04 nM
|
|
|
|
CP0378589
|
1-tert-butyl-3-[2-(3-methylphenoxy)-5-nitrophenyl]sulfonylurea
Show/Hide
|
C18H21N3O6S
|
2
|
| 1 |
IC50 = 17 nM
|
|
|
| 2 |
IC50 = 398 nM
|
|
|
|
CP0461922
|
1-tert-butyl-3-[2-(2,6-dimethylanilino)-5-nitrophenyl]sulfonylurea
Show/Hide
|
C19H24N4O5S
|
2
|
| 1 |
IC50 = 30.78 nM
|
|
|
| 2 |
IC50 = 56.89 nM
|
|
|
|
CP0378764
|
N-[2-(4-methylanilino)-5-nitrophenyl]sulfonylpiperidine-1-carboxamide
Show/Hide
|
C19H22N4O5S
|
2
|
| 1 |
IC50 = 38.52 nM
|
|
|
| 2 |
IC50 = 64.81 nM
|
|
|
|
CP0458627
|
4-chloro-N-[2-[3-[[3-(cyclopropylmethyl)-4-hydroxy-2-oxocyclopentyl]methyl]phenyl]ethyl]benzenesulfonamide
Show/Hide
|
C24H28ClNO4S
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0378590
|
1-butyl-3-[2-(2-methylphenoxy)-5-nitrophenyl]sulfonylurea
Show/Hide
|
C18H21N3O6S
|
2
|
| 1 |
IC50 = 42 nM
|
|
|
| 2 |
IC50 = 673 nM
|
|
|
|
CP0449523
|
1-[2-(4-bromo-3-methylanilino)-5-nitrophenyl]sulfonyl-3-pentylurea
Show/Hide
|
C19H23BrN4O5S
|
2
|
| 1 |
IC50 = 43.19 nM
|
|
|
| 2 |
IC50 = 126.28 nM
|
|
|
|
CP0449522
|
1-benzyl-3-[2-(4-methylanilino)-5-nitrophenyl]sulfonylurea
Show/Hide
|
C21H20N4O5S
|
2
|
| 1 |
IC50 = 45.01 nM
|
|
|
| 2 |
IC50 = 64.47 nM
|
|
|
|
CP0378768
|
1-[2-(3-methylanilino)-5-nitrophenyl]sulfonyl-3-pentylurea
Show/Hide
|
C19H24N4O5S
|
2
|
| 1 |
IC50 = 45.53 nM
|
|
|
| 2 |
IC50 = 60.39 nM
|
|
|
|
CP0449521
|
1-[2-(cyclohexylamino)-5-nitrophenyl]sulfonyl-3-hexylurea
Show/Hide
|
C19H30N4O5S
|
2
|
| 1 |
IC50 = 46.17 nM
|
|
|
| 2 |
IC50 = 81.22 nM
|
|
|
|
CP0378769
|
1-[2-(2,6-dimethylanilino)-5-nitrophenyl]sulfonyl-3-pentylurea
Show/Hide
|
C20H26N4O5S
|
2
|
| 1 |
IC50 = 47.1 nM
|
|
|
| 2 |
IC50 = 80.72 nM
|
|
|
|
CP0372448
|
1-tert-butyl-3-[2-(2-methoxy-4-methylphenoxy)-5-nitrophenyl]sulfonylurea
Show/Hide
|
C19H23N3O7S
|
2
|
| 1 |
IC50 = 52 nM
|
|
|
| 2 |
IC50 = 528 nM
|
|
|
|
CP0465139
|
1-butyl-3-[2-(4-methylphenoxy)-5-nitrophenyl]sulfonylurea
Show/Hide
|
C18H21N3O6S
|
2
|
| 1 |
IC50 = 52.89 nM
|
|
|
| 2 |
IC50 = 558.04 nM
|
|
|
|
CP0435610
|
1-(2-(p-toluidino)-5-nitrophenylsulfonyl)-3-tert-butylurea
Show/Hide
|
C18H22N4O5S
|
6
|
| 1 |
IC50 = 53 nM
|
|
|
| 2 |
IC50 = 53.1 nM
|
|
|
| 3 |
IC50 = 318.89 nM
|
|
|
| 4 |
IC50 = 319 nM
|
|
|
| 5 |
IC50 = 620 nM
|
|
|
| 6 |
IC50 = 700 nM
|
|
|
|
CP0461903
|
1-tert-butyl-3-[2-(4-methylphenyl)sulfanyl-5-nitrophenyl]sulfonylurea
Show/Hide
|
C18H21N3O5S2
|
2
|
| 1 |
IC50 = 55.17 nM
|
|
|
| 2 |
IC50 = 293.54 nM
|
|
|
|
CP0461921
|
1-[2-(4-methylphenoxy)-5-nitrophenyl]sulfonyl-3-pentylurea
Show/Hide
|
C19H23N3O6S
|
2
|
| 1 |
IC50 = 55.38 nM
|
|
|
| 2 |
IC50 = 139.32 nM
|
|
|
|
CP0465137
|
1-[2-(cyclohexylamino)-5-nitrophenyl]sulfonyl-3-heptylurea
Show/Hide
|
C20H32N4O5S
|
2
|
| 1 |
IC50 = 55.55 nM
|
|
|
| 2 |
IC50 = 92.9 nM
|
|
|
|
CP0465138
|
1-tert-butyl-3-[2-(4-methylphenoxy)-5-nitrophenyl]sulfonylurea
Show/Hide
|
C18H21N3O6S
|
2
|
| 1 |
IC50 = 57.63 nM
|
|
|
| 2 |
IC50 = 58.34 nM
|
|
|
|
CP0449519
|
1-hexyl-3-[2-(4-methylphenoxy)-5-nitrophenyl]sulfonylurea
Show/Hide
|
C20H25N3O6S
|
2
|
| 1 |
IC50 = 58.48 nM
|
|
|
| 2 |
IC50 = 526.42 nM
|
|
|
|
CP0434166
|
1-[2-(3-bromophenoxy)-5-nitrophenyl]sulfonyl-3-tert-butylurea
Show/Hide
|
C17H18BrN3O6S
|
2
|
| 1 |
IC50 = 59 nM
|
|
|
| 2 |
IC50 = 683 nM
|
|
|
|
CP0398474
|
3-[3-[2-[(4-chlorophenyl)sulfonylamino]ethyl]phenyl]propanoic acid
Show/Hide
|
C17H18ClNO4S
|
2
|
| 1 |
IC50 = 61 nM
|
|
|
| 2 |
Kd = 141 nM
|
|
|
|
CP0456095
|
4-chloro-N-[2-[3-[2-(2H-tetrazol-5-yl)ethyl]phenyl]ethyl]benzenesulfonamide
Show/Hide
|
C17H18ClN5O2S
|
2
|
| 1 |
IC50 = 64 nM
|
|
|
| 2 |
Kd = 331 nM
|
|
|
|
CP0464559
|
1-cyclohexyl-3-[2-(4-methylphenoxy)-5-nitrophenyl]sulfonylurea
Show/Hide
|
C20H23N3O6S
|
2
|
| 1 |
IC50 = 70.15 nM
|
|
|
| 2 |
IC50 = 600.71 nM
|
|
|
|
CP0496766
|
1-tert-butyl-3-[2-(3-chlorophenoxy)-5-nitrophenyl]sulfonylurea
Show/Hide
|
C17H18ClN3O6S
|
2
|
| 1 |
IC50 = 73 nM
|
|
|
| 2 |
IC50 = 698 nM
|
|
|
|
CP0453761
|
1-[2-(3,5-dimethylanilino)-5-nitrophenyl]sulfonyl-3-pentylurea
Show/Hide
|
C20H26N4O5S
|
2
|
| 1 |
IC50 = 76.5 nM
|
|
|
| 2 |
IC50 = 537.86 nM
|
|
|
|
CP0434165
|
1-tert-butyl-3-[2-(3-iodophenoxy)-5-nitrophenyl]sulfonylurea
Show/Hide
|
C17H18IN3O6S
|
2
|
| 1 |
IC50 = 95 nM
|
|
|
| 2 |
IC50 = 470 nM
|
|
|
|
CP0434196
|
1-[2-(4-chlorophenoxy)-5-nitrophenyl]sulfonyl-3-pentylurea
Show/Hide
|
C18H20ClN3O6S
|
2
|
| 1 |
IC50 = 98 nM
|
|
|
| 2 |
IC50 = 871 nM
|
|
|
|
CP0439625
|
1-tert-butyl-3-[2-(3-methoxyphenoxy)-5-nitrophenyl]sulfonylurea
Show/Hide
|
C18H21N3O7S
|
2
|
| 1 |
IC50 = 99 nM
|
|
|
| 2 |
IC50 = 1970 nM
|
|
|
|
CP0435674
|
1-tert-butyl-3-[2-(4-chloro-3-methylphenoxy)-5-nitrophenyl]sulfonylurea
Show/Hide
|
C18H20ClN3O6S
|
2
|
| 1 |
IC50 = 111 nM
|
|
|
| 2 |
IC50 = 1060 nM
|
|
|
|
CP0522283
|
1-[2-(4-bromophenoxy)-5-nitrophenyl]sulfonyl-3-pentylurea
Show/Hide
|
C18H20BrN3O6S
|
2
|
| 1 |
IC50 = 120 nM
|
|
|
| 2 |
IC50 = 1010 nM
|
|
|
|
CP0851881
|
4-Chloro-N-(3-((2-hydroxy-3-methyl-4-oxocyclopent-2-en-1-yl)methyl)phenethyl)benzenesulfonamide
Show/Hide
|
C21H22ClNO4S
|
2
|
| 1 |
IC50 = 131 nM
|
|
|
| 2 |
Kd = 328 nM
|
|
|
|
CP0496790
|
1-[2-(2-bromophenoxy)-5-nitrophenyl]sulfonyl-3-tert-butylurea
Show/Hide
|
C17H18BrN3O6S
|
2
|
| 1 |
IC50 = 151 nM
|
|
|
| 2 |
IC50 = 2580 nM
|
|
|
|
CP0434163
|
1-tert-butyl-3-[2-(4-methoxyphenoxy)-5-nitrophenyl]sulfonylurea
Show/Hide
|
C18H21N3O7S
|
2
|
| 1 |
IC50 = 152 nM
|
|
|
| 2 |
IC50 = 1940 nM
|
|
|
|
CP0511047
|
1-butyl-3-[2-(3-methylphenoxy)-5-nitrophenyl]sulfonylurea
Show/Hide
|
C18H21N3O6S
|
2
|
| 1 |
IC50 = 155 nM
|
|
|
| 2 |
IC50 = 1910 nM
|
|
|
|
CP0918581
|
4-Chloro-N-(3-((3-ethyl-4-hydroxy-2-oxocyclopent-3-en-1-yl)methyl)phenethyl)benzenesulfonamide
Show/Hide
|
C22H24ClNO4S
|
1
|
| 1 |
IC50 = 171 nM
|
|
|
|
CP0451658
|
1-(5-nitro-2-(o-tolyloxy)phenylsulfonyl)-3-pentylurea
Show/Hide
|
C19H23N3O6S
|
2
|
| 1 |
IC50 = 181 nM
|
|
|
| 2 |
IC50 = 1630 nM
|
|
|
|
CP0919286
|
4-Chloro-N-(3-((4-hydroxy-3-isopropyl-2-oxocyclopent-3-en-1-yl)methyl)phenethyl)benzenesulfonamide
Show/Hide
|
C23H26ClNO4S
|
1
|
| 1 |
IC50 = 198 nM
|
|
|
|
CP0378592
|
1-[2-(3-chlorophenoxy)-5-nitrophenyl]sulfonyl-3-pentylurea
Show/Hide
|
C18H20ClN3O6S
|
2
|
| 1 |
IC50 = 201 nM
|
|
|
| 2 |
IC50 = 2390 nM
|
|
|
|
CP0434167
|
1-[2-(3-methylphenoxy)-5-nitrophenyl]sulfonyl-3-propan-2-ylurea
Show/Hide
|
C17H19N3O6S
|
2
|
| 1 |
IC50 = 205 nM
|
|
|
| 2 |
IC50 = 2640 nM
|
|
|
|
CP0511040
|
1-tert-butyl-3-[2-(2-chlorophenoxy)-5-nitrophenyl]sulfonylurea
Show/Hide
|
C17H18ClN3O6S
|
2
|
| 1 |
IC50 = 205 nM
|
|
|
| 2 |
IC50 = 2420 nM
|
|
|
|
CP0399504
|
1-(5-nitro-2-(m-tolyloxy)phenylsulfonyl)-3-pentylurea
Show/Hide
|
C19H23N3O6S
|
2
|
| 1 |
IC50 = 223 nM
|
|
|
| 2 |
IC50 = 2530 nM
|
|
|
|
CP0434168
|
1-tert-butyl-3-[2-(2-methylphenoxy)-5-nitrophenyl]sulfonylurea
Show/Hide
|
C18H21N3O6S
|
2
|
| 1 |
IC50 = 233 nM
|
|
|
| 2 |
IC50 = 3760 nM
|
|
|
|
CP0894535
|
4-Chloro-N-(3-((2-hydroxy-4-oxocyclopent-2-en-1-yl)methyl)-phenethyl)benzenesulfonamide
Show/Hide
|
C20H20ClNO4S
|
2
|
| 1 |
IC50 = 250 nM
|
|
|
| 2 |
Kd = 203 nM
|
|
|
|
CP0464565
|
1-[2-(4-iodophenoxy)-5-nitrophenyl]sulfonyl-3-pentylurea
Show/Hide
|
C18H20IN3O6S
|
2
|
| 1 |
IC50 = 302 nM
|
|
|
| 2 |
IC50 = 2190 nM
|
|
|
|
CP0512682
|
4-chloro-N-[2-[3-[[(2-hydroxy-3,4-dioxocyclobuten-1-yl)amino]methyl]phenyl]ethyl]benzenesulfonamide
Show/Hide
|
C19H17ClN2O5S
|
2
|
| 1 |
IC50 = 377 nM
|
|
|
| 2 |
Kd = 359 nM
|
|
|
|
CP0460083
|
1-[2-(2-chlorophenoxy)-5-nitrophenyl]sulfonyl-3-pentylurea
Show/Hide
|
C18H20ClN3O6S
|
2
|
| 1 |
IC50 = 387 nM
|
|
|
| 2 |
IC50 = 3060 nM
|
|
|
|
CP0435676
|
1-tert-butyl-3-[2-(4-chlorophenoxy)-5-nitrophenyl]sulfonylurea
Show/Hide
|
C17H18ClN3O6S
|
2
|
| 1 |
IC50 = 400 nM
|
|
|
| 2 |
IC50 = 3050 nM
|
|
|
|
CP0378556
|
1-tert-butyl-3-[2-(4-iodophenoxy)-5-nitrophenyl]sulfonylurea
Show/Hide
|
C17H18IN3O6S
|
2
|
| 1 |
IC50 = 401 nM
|
|
|
| 2 |
IC50 = 2150 nM
|
|
|
|
CP0434198
|
1-[2-(3-bromophenoxy)-5-nitrophenyl]sulfonyl-3-pentylurea
Show/Hide
|
C18H20BrN3O6S
|
2
|
| 1 |
IC50 = 413 nM
|
|
|
| 2 |
IC50 = 5860 nM
|
|
|
|
CP0467254
|
1-[2-(2-bromophenoxy)-5-nitrophenyl]sulfonyl-3-pentylurea
Show/Hide
|
C18H20BrN3O6S
|
2
|
| 1 |
IC50 = 423 nM
|
|
|
| 2 |
IC50 = 3130 nM
|
|
|
|
CP0435675
|
1-[2-(4-methoxyphenoxy)-5-nitrophenyl]sulfonyl-3-pentylurea
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C19H23N3O7S
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2
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| 1 |
IC50 = 446 nM
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| 2 |
IC50 = 2670 nM
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CP0463027
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1-[2-(4-methylphenoxy)-5-nitrophenyl]sulfonyl-3-propylurea
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C17H19N3O6S
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2
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| 1 |
IC50 = 448 nM
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| 2 |
IC50 = 4220 nM
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CP0378591
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1-[2-(2-methylphenoxy)-5-nitrophenyl]sulfonyl-3-propan-2-ylurea
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C17H19N3O6S
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2
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| 1 |
IC50 = 501 nM
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| 2 |
IC50 = 8750 nM
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CP0464566
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1-[2-(4-bromophenoxy)-5-nitrophenyl]sulfonyl-3-tert-butylurea
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C17H18BrN3O6S
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2
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| 1 |
IC50 = 523 nM
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| 2 |
IC50 = 1660 nM
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CP0437105
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1-[2-(4-chloro-3-methylphenoxy)-5-nitrophenyl]sulfonyl-3-pentylurea
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C19H22ClN3O6S
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2
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| 1 |
IC50 = 565 nM
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| 2 |
IC50 = 3720 nM
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CP0372473
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2-tert-butyl-1-cyano-3-[2-(4-methylphenoxy)-5-nitrophenyl]sulfonylguanidine
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C19H21N5O5S
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2
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| 1 |
IC50 = 579 nM
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| 2 |
IC50 = 2080 nM
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CP0434236
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1-[5-cyano-2-(4-methylphenoxy)phenyl]sulfonyl-3-pentylurea
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C20H23N3O4S
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2
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| 1 |
IC50 = 630 nM
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| 2 |
IC50 = 900 nM
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CP0395986
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1-tert-butyl-3-[5-cyano-2-(4-methylphenoxy)phenyl]sulfonylurea
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C19H21N3O4S
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2
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| 1 |
IC50 = 680 nM
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| 2 |
IC50 = 750 nM
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CP0477624
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1-[5-cyano-2-(3-methylphenoxy)phenyl]sulfonyl-3-pentylurea
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C20H23N3O4S
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2
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| 1 |
IC50 = 680 nM
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| 2 |
IC50 = 1330 nM
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CP0434237
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1-tert-butyl-3-[5-cyano-2-(3-methylphenoxy)phenyl]sulfonylurea
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C19H21N3O4S
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2
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| 1 |
IC50 = 690 nM
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| 2 |
IC50 = 1050 nM
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CP0524359
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1-[2-(4-ethoxyphenoxy)-5-nitrophenyl]sulfonyl-3-pentylurea
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C20H25N3O7S
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2
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| 1 |
IC50 = 749 nM
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| 2 |
IC50 = 13560 nM
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CP0435677
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1-[2-(4-methylphenoxy)-5-nitrophenyl]sulfonyl-3-propan-2-ylurea
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C17H19N3O6S
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2
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| 1 |
IC50 = 843 nM
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| 2 |
IC50 = 8760 nM
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CP0457256
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1-tert-butyl-3-[5-cyano-2-(4-methylanilino)phenyl]sulfonylurea
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C19H22N4O3S
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2
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| 1 |
IC50 = 850 nM
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| 2 |
IC50 = 1040 nM
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CP0505092
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1-tert-butyl-3-[5-nitro-2-(4-propoxyphenoxy)phenyl]sulfonylurea
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C20H25N3O7S
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2
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| 1 |
IC50 = 875 nM
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| 2 |
IC50 = 10760 nM
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CP0460100
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1-[2-(3-iodophenoxy)-5-nitrophenyl]sulfonyl-3-pentylurea
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C18H20IN3O6S
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2
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| 1 |
IC50 = 885 nM
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| 2 |
IC50 = 4520 nM
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CP0434230
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1-[5-cyano-2-(4-methylanilino)phenyl]sulfonyl-3-pentylurea
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C20H24N4O3S
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2
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| 1 |
IC50 = 1040 nM
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| 2 |
IC50 = 2060 nM
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CP0528173
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1-tert-butyl-3-[2-(4-ethoxyphenoxy)-5-nitrophenyl]sulfonylurea
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C19H23N3O7S
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2
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| 1 |
IC50 = 1100 nM
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| 2 |
IC50 = 19190 nM
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CP0477619
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1-[5-cyano-2-(4-methylphenoxy)phenyl]sulfonyl-3-propan-2-ylurea
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C18H19N3O4S
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2
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| 1 |
IC50 = 1350 nM
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| 2 |
IC50 = 3050 nM
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CP0378944
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1-tert-butyl-3-[5-cyano-2-(2-methylphenoxy)phenyl]sulfonylurea
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C19H21N3O4S
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2
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| 1 |
IC50 = 1470 nM
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| 2 |
IC50 = 3690 nM
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CP0407141
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1-tert-butyl-3-[5-cyano-2-(3-methylanilino)phenyl]sulfonylurea
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C19H22N4O3S
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2
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| 1 |
IC50 = 1590 nM
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| 2 |
IC50 = 2200 nM
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CP0434238
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1-[5-cyano-2-(3-methylphenoxy)phenyl]sulfonyl-3-propan-2-ylurea
Show/Hide
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C18H19N3O4S
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2
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| 1 |
IC50 = 1690 nM
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| 2 |
IC50 = 2380 nM
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CP0477625
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1-[5-cyano-2-(2-methylphenoxy)phenyl]sulfonyl-3-pentylurea
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C20H23N3O4S
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2
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| 1 |
IC50 = 1780 nM
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| 2 |
IC50 = 2240 nM
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CP0272414
|
US11149018, Example 34
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C26H27BrClN3O3
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1
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| 1 |
IC50 = 2200 nM
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CP0446483
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1-[5-cyano-2-(3-methylanilino)phenyl]sulfonyl-3-pentylurea
Show/Hide
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C20H24N4O3S
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2
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| 1 |
IC50 = 2330 nM
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| 2 |
IC50 = 2950 nM
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CP0434234
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1-tert-butyl-3-[5-cyano-2-(2-methylanilino)phenyl]sulfonylurea
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C19H22N4O3S
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2
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| 1 |
IC50 = 2750 nM
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| 2 |
IC50 = 4780 nM
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CP0407146
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1-[5-cyano-2-(2-methylanilino)phenyl]sulfonyl-3-pentylurea
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C20H24N4O3S
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2
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| 1 |
IC50 = 3190 nM
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| 2 |
IC50 = 7850 nM
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CP0478834
|
4-chloro-N-[2-[3-[[3-ethyl-4-(2-methylpropoxy)-2-oxocyclopent-3-en-1-yl]methyl]phenyl]ethyl]benzenesulfonamide
Show/Hide
|
C26H32ClNO4S
|
1
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| 1 |
IC50 = 3801 nM
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CP0480428
|
1-tert-butyl-3-[5-cyano-2-(4-fluorophenoxy)phenyl]sulfonylurea
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C18H18FN3O4S
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2
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| 1 |
IC50 = 3890 nM
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| 2 |
IC50 = 4350 nM
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CP0434231
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1-[5-cyano-2-(4-methylanilino)phenyl]sulfonyl-3-propan-2-ylurea
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C18H20N4O3S
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2
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| 1 |
IC50 = 4110 nM
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| 2 |
IC50 = 4220 nM
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CP0477617
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1-tert-butyl-3-[5-cyano-2-(4-fluoroanilino)phenyl]sulfonylurea
Show/Hide
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C18H19FN4O3S
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2
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| 1 |
IC50 = 4640 nM
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| 2 |
IC50 = 4910 nM
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CP0434160
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1-[5-nitro-2-(4-propoxyphenoxy)phenyl]sulfonyl-3-pentylurea
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C21H27N3O7S
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2
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| 1 |
IC50 = 4840 nM
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| 2 |
IC50 = 27230 nM
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CP0434229
|
1-tert-butyl-3-[2-(4-chlorophenoxy)-5-cyanophenyl]sulfonylurea
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C18H18ClN3O4S
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2
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| 1 |
IC50 = 5270 nM
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| 2 |
IC50 = 5640 nM
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CP0512820
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4-chloro-N-[2-[3-[[4-(2-methylpropoxy)-2-oxo-3-propan-2-ylcyclopent-3-en-1-yl]methyl]phenyl]ethyl]benzenesulfonamide
Show/Hide
|
C27H34ClNO4S
|
1
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| 1 |
IC50 = 5303 nM
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CP0454134
|
1-[2-(4-bromophenoxy)-5-cyanophenyl]sulfonyl-3-tert-butylurea
Show/Hide
|
C18H18BrN3O4S
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2
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| 1 |
IC50 = 5310 nM
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| 2 |
IC50 = 5880 nM
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CP0480426
|
1-tert-butyl-3-[5-cyano-2-(4-iodophenoxy)phenyl]sulfonylurea
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C18H18IN3O4S
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2
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| 1 |
IC50 = 5520 nM
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| 2 |
IC50 = 5540 nM
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CP0477626
|
1-[5-cyano-2-(2-methylphenoxy)phenyl]sulfonyl-3-propan-2-ylurea
Show/Hide
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C18H19N3O4S
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2
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| 1 |
IC50 = 6130 nM
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| 2 |
IC50 = 8680 nM
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CP0407140
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1-[5-cyano-2-(4-fluoroanilino)phenyl]sulfonyl-3-pentylurea
Show/Hide
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C19H21FN4O3S
|
2
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| 1 |
IC50 = 6450 nM
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| 2 |
IC50 = 6780 nM
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CP0508900
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1-[5-cyano-2-(2-methylanilino)phenyl]sulfonyl-3-propan-2-ylurea
Show/Hide
|
C18H20N4O3S
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2
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| 1 |
IC50 = 7240 nM
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| 2 |
IC50 = 10120 nM
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CP0407619
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1-[5-cyano-2-(4-fluoroanilino)phenyl]sulfonyl-3-propan-2-ylurea
Show/Hide
|
C17H17FN4O3S
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2
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| 1 |
IC50 = 7830 nM
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| 2 |
IC50 = 8170 nM
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CP0480427
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1-[2-(4-chlorophenoxy)-5-cyanophenyl]sulfonyl-3-propan-2-ylurea
Show/Hide
|
C17H16ClN3O4S
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2
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| 1 |
IC50 = 8490 nM
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| 2 |
IC50 = 9460 nM
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CP0477618
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1-[2-(4-bromophenoxy)-5-cyanophenyl]sulfonyl-3-pentylurea
Show/Hide
|
C19H20BrN3O4S
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2
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| 1 |
IC50 = 8520 nM
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| 2 |
IC50 = 9540 nM
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CP0407143
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1-[2-(4-chlorophenoxy)-5-cyanophenyl]sulfonyl-3-pentylurea
Show/Hide
|
C19H20ClN3O4S
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2
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| 1 |
IC50 = 8640 nM
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| 2 |
IC50 = 8720 nM
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CP0482515
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1-[5-cyano-2-(3-methylanilino)phenyl]sulfonyl-3-propan-2-ylurea
Show/Hide
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C18H20N4O3S
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2
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| 1 |
IC50 = 9110 nM
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| 2 |
IC50 = 9500 nM
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CP0407142
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1-[2-(4-bromophenoxy)-5-cyanophenyl]sulfonyl-3-propan-2-ylurea
Show/Hide
|
C17H16BrN3O4S
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2
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| 1 |
IC50 = 9130 nM
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| 2 |
IC50 = 9470 nM
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CP0446482
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1-[5-cyano-2-(4-fluorophenoxy)phenyl]sulfonyl-3-propan-2-ylurea
Show/Hide
|
C17H16FN3O4S
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2
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| 1 |
IC50 = 9300 nM
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| 2 |
IC50 = 9620 nM
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CP0407145
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1-[5-cyano-2-(4-fluorophenoxy)phenyl]sulfonyl-3-pentylurea
Show/Hide
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C19H20FN3O4S
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2
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| 1 |
IC50 = 9430 nM
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| 2 |
IC50 = 9530 nM
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CP0446478
|
1-[5-cyano-2-(4-iodophenoxy)phenyl]sulfonyl-3-pentylurea
Show/Hide
|
C19H20IN3O4S
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2
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| 1 |
IC50 = 9490 nM
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| 2 |
IC50 = 9520 nM
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CP0508899
|
1-[5-cyano-2-(4-iodophenoxy)phenyl]sulfonyl-3-propan-2-ylurea
Show/Hide
|
C17H16IN3O4S
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2
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| 1 |
IC50 = 9490 nM
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| 2 |
IC50 = 9520 nM
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CP0795225
|
1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylaminocarbonyl)oxime
Show/Hide
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C19H16N2O2S
|
1
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| 1 |
IC50 > 10000 nM
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CP0501552
|
4-chloro-N-[2-[3-[[3-methyl-4-(2-methylpropoxy)-2-oxocyclopent-3-en-1-yl]methyl]phenyl]ethyl]benzenesulfonamide
Show/Hide
|
C25H30ClNO4S
|
1
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| 1 |
IC50 > 10000 nM
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CP0851880
|
4-Chloro-N-(3-(2-(2-hydroxy-5-oxocyclopent-1-en-1-yl)-ethyl)phenethyl)benzenesulfonamide
Show/Hide
|
C21H22ClNO4S
|
1
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| 1 |
IC50 > 10000 nM
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CP0919739
|
4-Chloro-N-(3-((2-hydroxy-5-oxocyclopent-1-en-1-yl)methyl)-phenethyl)benzenesulfonamide
Show/Hide
|
C20H20ClNO4S
|
2
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| 1 |
IC50 > 10000 nM
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| 2 |
Kd = 11400 nM
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CP0478832
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4-chloro-N-[2-[3-(3-hydroxypropyl)phenyl]ethyl]benzenesulfonamide
Show/Hide
|
C17H20ClNO3S
|
2
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| 1 |
IC50 = 15117 nM
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| 2 |
Kd > 10000 nM
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CP0512819
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4-chloro-N-[2-[3-[[3-(cyclopropylmethyl)-4-(2-methylpropoxy)-2-oxocyclopent-3-en-1-yl]methyl]phenyl]ethyl]benzenesulfonamide
Show/Hide
|
C28H34ClNO4S
|
1
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| 1 |
IC50 = 21853 nM
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CP0042409
|
2-[2-[4-(4-ethylphenyl)benzoyl]-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid
Show/Hide
|
C28H26N2O3
|
1
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| 1 |
IC50 > 25000 nM
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CP0042410
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2-[8-chloro-2-(naphthalene-1-carbonyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid
Show/Hide
|
C24H19ClN2O3
|
1
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| 1 |
IC50 > 25000 nM
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CP0045673
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2-[2-(3-chlorobenzoyl)-8-fluoro-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid
Show/Hide
|
C20H16ClFN2O3
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1
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| 1 |
IC50 > 25000 nM
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CP0055416
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2-[2-(naphthalene-1-carbonyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid
Show/Hide
|
C24H20N2O3
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1
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| 1 |
IC50 > 25000 nM
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CP0055418
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2-[6-chloro-2-(3-chlorobenzoyl)-8-fluoro-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid
Show/Hide
|
C20H15Cl2FN2O3
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1
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| 1 |
IC50 > 25000 nM
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CP0055420
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2-[2-(3-chlorobenzoyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid
Show/Hide
|
C20H17ClN2O3
|
1
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| 1 |
IC50 > 25000 nM
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CP0055873
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2-[8-fluoro-2-[2-(1H-indol-3-yl)acetyl]-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid
Show/Hide
|
C23H20FN3O3
|
1
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| 1 |
IC50 > 25000 nM
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CP0055874
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2-[8-fluoro-2-(thiophene-2-carbonyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid
Show/Hide
|
C18H15FN2O3S
|
1
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| 1 |
IC50 > 25000 nM
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CP0055877
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2-[2-benzoyl-8-(trifluoromethyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid
Show/Hide
|
C21H17F3N2O3
|
1
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| 1 |
IC50 > 25000 nM
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CP0070143
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2-(2-benzoyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)acetic acid
Show/Hide
|
C20H18N2O3
|
1
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| 1 |
IC50 > 25000 nM
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CP0083568
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2-[8-fluoro-2-(3-naphthalen-1-ylpropanoyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid
Show/Hide
|
C26H23FN2O3
|
1
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| 1 |
IC50 > 25000 nM
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CP0086399
|
2-[6-chloro-2-[4-(4-ethylphenyl)benzoyl]-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid
Show/Hide
|
C28H25ClN2O3
|
1
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| 1 |
IC50 > 25000 nM
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CP0086409
|
2-[8-fluoro-2-(2-naphthalen-1-ylacetyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid
Show/Hide
|
C25H21FN2O3
|
1
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| 1 |
IC50 > 25000 nM
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|
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CP0087804
|
ACT-129968
Show/Hide
|
C24H19FN2O3
|
1
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| 1 |
IC50 > 25000 nM
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CP0130562
|
2-[8-methyl-2-(naphthalene-1-carbonyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid
Show/Hide
|
C25H22N2O3
|
1
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| 1 |
IC50 > 25000 nM
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|
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CP0156867
|
2-[2-(cyclohexanecarbonyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid
Show/Hide
|
C20H24N2O3
|
1
|
| 1 |
IC50 > 25000 nM
|
|
|
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CP0156868
|
2-[6-chloro-8-fluoro-2-(naphthalene-1-carbonyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid
Show/Hide
|
C24H18ClFN2O3
|
1
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| 1 |
IC50 > 25000 nM
|
|
|
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CP0199029
|
2-(2-benzoyl-8-propan-2-yl-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)acetic acid
Show/Hide
|
C23H24N2O3
|
1
|
| 1 |
IC50 > 25000 nM
|
|
|
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CP0199053
|
2-(2-benzoyl-8-methoxy-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)acetic acid
Show/Hide
|
C21H20N2O4
|
1
|
| 1 |
IC50 > 25000 nM
|
|
|
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CP0261961
|
2-[2-(naphthalene-1-carbonyl)-8-(trifluoromethyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid
Show/Hide
|
C25H19F3N2O3
|
1
|
| 1 |
IC50 > 25000 nM
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|
|
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CP0343798
|
2-[(3R)-4-[(4-chlorophenyl)methyl]-7-fluoro-5-methylsulfonyl-2,3-dihydro-1H-cyclopenta[b]indol-3-yl]acetic acid
Show/Hide
|
C21H19ClFNO4S
|
2
|
| 1 |
Kd = 10.9 nM
|
|
|
| 2 |
Ki = 2.95 nM
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CP0374187
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2-[(3R)-5-bromo-4-[(4-chlorophenyl)methyl]-7-fluoro-2,3-dihydro-1H-cyclopenta[b]indol-3-yl]acetic acid
Show/Hide
|
C20H16BrClFNO2
|
1
|
| 1 |
Ki = 0.84 nM
|
|
|
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CP0511596
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(+/-)-2-(5-(2,4-dichlorophenylthio)-4-(methylsulfonyl)-6,7,8,9-tetrahydropyrido[3,2-b]indolizin-6-yl)acetic acid
Show/Hide
|
C20H18Cl2N2O4S2
|
1
|
| 1 |
Ki = 3.8 nM
|
|
|
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CP0481324
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(+/-)-2-(5-(4-chlorophenylthio)-4-isopropyl-6,7,8,9-tetrahydropyrido[3,2-b]indolizin-6-yl)acetic acid
Show/Hide
|
C22H23ClN2O2S
|
1
|
| 1 |
Ki = 7 nM
|
|
|
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CP0481322
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(+/-)-2-(5-(3,4-dichlorophenylthio)-4-isopropyl-6,7,8,9-tetrahydropyrido[3,2-b]indolizin-6-yl)acetic acid
Show/Hide
|
C22H22Cl2N2O2S
|
1
|
| 1 |
Ki = 13.9 nM
|
|
|
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CP0372074
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2-[(3R)-5-acetyl-4-[(4-chlorophenyl)methyl]-7-fluoro-2,3-dihydro-1H-cyclopenta[b]indol-3-yl]acetic acid
Show/Hide
|
C22H19ClFNO3
|
1
|
| 1 |
Ki = 14 nM
|
|
|
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CP0374146
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(+/-)-2-(5-(2,3-dichlorophenylthio)-4-(methylsulfonyl)-6,7,8,9-tetrahydropyrido[3,2-b]indolizin-6-yl)acetic acid
Show/Hide
|
C20H18Cl2N2O4S2
|
1
|
| 1 |
Ki = 17.9 nM
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|
|
|
CP0048953
|
(R)-3-(3-(4-fluorophenylsulfonamido)-1,2,3,4-tetrahydrocarbazol-9-yl)propanoic acid
Show/Hide
|
C21H21FN2O4S
|
1
|
| 1 |
Ki = 18 nM
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|
|
|
CP0481331
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(+/-)-2-(5-(3,4-dichlorophenylthio)-4-(methylsulfonyl)-6,7,8,9-tetrahydropyrido[3,2-b]indolizin-6-yl)acetic acid
Show/Hide
|
C20H18Cl2N2O4S2
|
1
|
| 1 |
Ki = 23.1 nM
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|
|
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CP0532090
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(+/-)-2-(5-(2-chloro-4-fluorophenylthio)-4-(methylsulfonyl)-6,7,8,9-tetrahydropyrido[3,2-b]indolizin-6-yl)acetic acid
Show/Hide
|
C20H18ClFN2O4S2
|
1
|
| 1 |
Ki = 24.5 nM
|
|
|
|
CP0415782
|
(+/-)-2-(5-(4-bromophenylthio)-4-(methylsulfonyl)-6,7,8,9-tetrahydropyrido[3,2-b]indolizin-6-yl)acetic acid
Show/Hide
|
C20H19BrN2O4S2
|
1
|
| 1 |
Ki = 35.7 nM
|
|
|
|
CP0422463
|
1-(2,6-dimethoxyphenyl)-N-[[3-methyl-4-[6-oxo-5,9-bis(2,2,2-trifluoroethoxy)-8H-pyrrolo[3,4-g]quinolin-7-yl]phenyl]methylsulfonyl]cyclopropane-1-carboxamide
Show/Hide
|
C35H31F6N3O8S
|
1
|
| 1 |
Ki = 39 nM
|
|
|
|
CP0374149
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(+/-)-2-(5-(4-chlorophenylthio)-4-(methylsulfonyl)-6,7,8,9-tetrahydropyrido[3,2-b]indolizin-6-yl)acetic acid
Show/Hide
|
C20H19ClN2O4S2
|
1
|
| 1 |
Ki = 39.4 nM
|
|
|
|
CP0384700
|
(+/-)-2-(4-(methylsulfonyl)-5-(naphthalen-1-ylthio)-6,7,8,9-tetrahydropyrido[3,2-b]indolizin-6-yl)acetic acid
Show/Hide
|
C24H22N2O4S2
|
1
|
| 1 |
Ki = 41.5 nM
|
|
|
|
CP0415783
|
(+/-)-2-(4-(methylsulfonyl)-5-(4-(trifluoromethyl)phenylthio)-6,7,8,9-tetrahydropyrido[3,2-b]indolizin-6-yl)acetic acid
Show/Hide
|
C21H19F3N2O4S2
|
1
|
| 1 |
Ki = 64.8 nM
|
|
|
|
CP0522859
|
(+/-)-2-(5-(4-chlorophenylthio)-4-(methylthio)-6,7,8,9-tetrahydropyrido[3,2-b]indolizin-6-yl)acetic acid
Show/Hide
|
C20H19ClN2O2S2
|
1
|
| 1 |
Ki = 78.9 nM
|
|
|
|
CP0466500
|
(+/-)-2-(4-(methylsulfonyl)-5-(p-tolylthio)-6,7,8,9-tetrahydropyrido[3,2-b]indolizin-6-yl)acetic acid
Show/Hide
|
C21H22N2O4S2
|
1
|
| 1 |
Ki = 171.6 nM
|
|
|
|
CP0481332
|
2-(1-isopropyl-9-(2,4,5-trichlorophenylthio)-7,8-dihydro-6H-pyrido[3,4-b]pyrrolizin-8-yl)acetic acid
Show/Hide
|
C21H19Cl3N2O2S
|
1
|
| 1 |
Ki = 186 nM
|
|
|
|
CP0415784
|
(+/-)-2-(5-(4-chlorophenylthio)-4-methoxy-6,7,8,9-tetrahydropyrido[3,2-b]indolizin-6-yl)acetic acid
Show/Hide
|
C20H19ClN2O3S
|
1
|
| 1 |
Ki = 339.8 nM
|
|
|
|
CP0504216
|
2-(9-(2,4-dichlorophenylthio)-1-isopropyl-7,8-dihydro-6H-pyrido[3,4-b]pyrrolizin-8-yl)acetic acid
Show/Hide
|
C21H20Cl2N2O2S
|
1
|
| 1 |
Ki = 387 nM
|
|
|
|
CP0495587
|
2-(1-cyclopropyl-9-(3,4-dichlorophenylthio)-7,8-dihydro-6H-pyrido[3,4-b]pyrrolizin-8-yl)acetic acid
Show/Hide
|
C21H18Cl2N2O2S
|
1
|
| 1 |
Ki = 415 nM
|
|
|
|
CP0484976
|
2-(10-(3,4-dichlorophenylthio)-1-isopropyl-6,7,8,9-tetrahydropyrido[3,4-b]indolizin-9-yl)acetic acid
Show/Hide
|
C22H22Cl2N2O2S
|
1
|
| 1 |
Ki = 468 nM
|
|
|
|
CP0481330
|
2-(1-(cyclopropylmethyl)-10-(3,4-dichlorophenylthio)-6,7,8,9-tetrahydropyrido[3,4-b]indolizin-9-yl)acetic acid
Show/Hide
|
C23H22Cl2N2O2S
|
1
|
| 1 |
Ki = 587 nM
|
|
|
|
CP0504213
|
2-(10-(3,4-dichlorophenylthio)-1-propyl-6,7,8,9-tetrahydropyrido[3,4-b]indolizin-9-yl)acetic acid
Show/Hide
|
C22H22Cl2N2O2S
|
1
|
| 1 |
Ki = 626 nM
|
|
|
|
CP0393748
|
N-[[4-(5,9-diethoxy-6-oxo-8H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylphenyl]methylsulfonyl]-2-(2-methoxyphenyl)acetamide
Show/Hide
|
C32H33N3O7S
|
1
|
| 1 |
Ki = 630 nM
|
|
|
|
CP0374147
|
(+/-)-2-(4-(methylsulfonyl)-5-(phenylthio)-6,7,8,9-tetrahydropyrido[3,2-b]indolizin-6-yl)acetic acid
Show/Hide
|
C20H20N2O4S2
|
1
|
| 1 |
Ki = 646.4 nM
|
|
|
|
CP0374148
|
2-(10-(3,4-dichlorophenylthio)-1-ethyl-6,7,8,9-tetrahydropyrido[3,4-b]indolizin-9-yl)acetic acid
Show/Hide
|
C21H20Cl2N2O2S
|
1
|
| 1 |
Ki = 687 nM
|
|
|
|
CP0127253
|
(R)-2-(9-(3,4-dichlorophenylthio)-1-isopropyl-7,8-dihydro-6H-pyrido[3,4-b]pyrrolizin-8-yl)acetic acid
Show/Hide
|
C21H20Cl2N2O2S
|
1
|
| 1 |
Ki = 935 nM
|
|
|
|
CP0481329
|
2-(1-cyclopropyl-10-(3,4-dichlorophenylthio)-6,7,8,9-tetrahydropyrido[3,4-b]indolizin-9-yl)acetic acid
Show/Hide
|
C22H20Cl2N2O2S
|
1
|
| 1 |
Ki = 990 nM
|
|
|
|
CP0506252
|
2-(10-(3,4-dichlorophenylthio)-1-(methylsulfonyl)-6,7,8,9-tetrahydropyrido[3,4-b]indolizin-9-yl)acetic acid
Show/Hide
|
C20H18Cl2N2O4S2
|
1
|
| 1 |
Ki = 995 nM
|
|
|
|
CP0378877
|
(S)-2-(4-(4-chlorobenzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid
Show/Hide
|
C21H19ClFNO4S
|
1
|
| 1 |
Ki = 1050 nM
|
|
|
|
CP0108218
|
(R)-2-(4-(4-chlorobenzyl)-5-acetyl-7-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid
Show/Hide
|
C23H22ClNO5S
|
1
|
| 1 |
Ki = 1200 nM
|
|
|
|
CP0485660
|
3-[6-(4-Fluoro-benzenesulfonylamino)-1,2,3,4-tetrahydro-carbazol-9-yl]-propionic acid
Show/Hide
|
C21H21FN2O4S
|
1
|
| 1 |
Ki = 1500 nM
|
|
|
|
CP0506253
|
2-(9-(3,4-dichlorophenylthio)-1-ethyl-7,8-dihydro-6H-pyrido[3,4-b]pyrrolizin-8-yl)acetic acid
Show/Hide
|
C20H18Cl2N2O2S
|
1
|
| 1 |
Ki = 1687 nM
|
|
|
|
CP0415785
|
2-(9-(3,4-dichlorophenylthio)-1-isopropyl-7,8-dihydro-6H-pyrido[3,4-b]pyrrolizin-8-yl)acetic acid
Show/Hide
|
C21H20Cl2N2O2S
|
1
|
| 1 |
Ki = 2081 nM
|
|
|
|
CP0484972
|
2-(9-(4-chlorophenylthio)-1-isopropyl-7,8-dihydro-6H-pyrido[3,4-b]pyrrolizin-8-yl)acetic acid
Show/Hide
|
C21H21ClN2O2S
|
1
|
| 1 |
Ki = 2813 nM
|
|
|
|
CP0417338
|
2-(9-(3,4-dichlorophenylthio)-7,8-dihydro-6H-pyrido[3,4-b]pyrrolizin-8-yl)acetic acid
Show/Hide
|
C18H14Cl2N2O2S
|
1
|
| 1 |
Ki = 2917 nM
|
|
|
|
CP0440738
|
2-(1-(cyclopropylmethyl)-9-(3,4-dichlorophenylthio)-7,8-dihydro-6H-pyrido[3,4-b]pyrrolizin-8-yl)acetic acid
Show/Hide
|
C22H20Cl2N2O2S
|
1
|
| 1 |
Ki = 3428 nM
|
|
|
|
CP0032668
|
(R)-2-(7-(4-fluoro-N-methylphenylsulfonamido)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl)acetic acid
Show/Hide
|
C21H21FN2O4S
|
1
|
| 1 |
Ki = 3804 nM
|
|
|
|
CP0124158
|
(S)-2-(9-(3,4-dichlorophenylthio)-1-isopropyl-7,8-dihydro-6H-pyrido[3,4-b]pyrrolizin-8-yl)acetic acid
Show/Hide
|
C21H20Cl2N2O2S
|
1
|
| 1 |
Ki = 5039 nM
|
|
|
|
CP0511597
|
2-(1-isopropyl-9-(4-(trifluoromethyl)phenylthio)-7,8-dihydro-6H-pyrido[3,4-b]pyrrolizin-8-yl)acetic acid
Show/Hide
|
C22H21F3N2O2S
|
1
|
| 1 |
Ki = 6144 nM
|
|
|
|
CP0384698
|
2-(9-(3,4-dichlorophenylthio)-1-(methylsulfonyl)-7,8-dihydro-6H-pyrido[3,4-b]pyrrolizin-8-yl)acetic acid
Show/Hide
|
C19H16Cl2N2O4S2
|
1
|
| 1 |
Ki = 6887 nM
|
|
|
|
CP0041889
|
2-((R)-4-(4-chlorobenzyl)-5-(1-hydroxyethyl)-7-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid
Show/Hide
|
C23H24ClNO5S
|
1
|
| 1 |
Ki = 7100 nM
|
|
|
|
CP0481326
|
2-(9-(4-chlorophenylthio)-1-(methylsulfonyl)-7,8-dihydro-6H-pyrido[3,4-b]pyrrolizin-8-yl)acetic acid
Show/Hide
|
C19H17ClN2O4S2
|
1
|
| 1 |
Ki = 12183 nM
|
|
|
|
CP0379209
|
2-[6-[(4-fluorophenyl)sulfonylamino]-3-methyl-1,2,3,4-tetrahydrocarbazol-9-yl]acetic acid
Show/Hide
|
C21H21FN2O4S
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0432914
|
2-[2-[(4-fluorophenyl)sulfonylamino]-6,7,8,9,10,10a-hexahydro-5aH-cyclohepta[b]indol-5-yl]acetic acid
Show/Hide
|
C21H23FN2O4S
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0485909
|
2-[6-[(4-fluorophenyl)sulfonylamino]-3-phenyl-1,2,3,4-tetrahydrocarbazol-9-yl]acetic acid
Show/Hide
|
C26H23FN2O4S
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0372689
|
2-[6-[(4-fluorophenyl)sulfonylamino]-1,2,3,4-tetrahydrocarbazol-9-yl]acetic acid
Show/Hide
|
C20H19FN2O4S
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0481328
|
2-(9-(3,4-dichlorophenylthio)-1-phenyl-7,8-dihydro-6H-pyrido[3,4-b]pyrrolizin-8-yl)acetic acid
Show/Hide
|
C24H18Cl2N2O2S
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0484977
|
2-(9-(2,6-dichlorophenylthio)-1-isopropyl-7,8-dihydro-6H-pyrido[3,4-b]pyrrolizin-8-yl)acetic acid
Show/Hide
|
C21H20Cl2N2O2S
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0501728
|
(R)-2-(8-(2-(4-fluorophenyl)-N,2-dimethylpropanamido)-6,7,8,9-tetrahydropyrido[3,2-b]indolizin-5-yl)acetic acid
Show/Hide
|
C24H26FN3O3
|
1
|
| 1 |
Ki > 21000 nM
|
|
|
|
CP0143839
|
(R)-2-(8-(4-fluoro-N-methylphenylsulfonamido)-6,7,8,9-tetrahydropyrido[3,2-b]indolizin-5-yl)acetic acid
Show/Hide
|
C20H20FN3O4S
|
1
|
| 1 |
Ki > 22000 nM
|
|
|
|
CP0410059
|
2-((R)-8-((S)-2-(4-fluorophenyl)-N-methylpropanamido)-6,7,8,9-tetrahydropyrido[3,2-b]indolizin-5-yl)acetic acid
Show/Hide
|
C23H24FN3O3
|
1
|
| 1 |
Ki > 22000 nM
|
|
|
|
CP0499090
|
(R)-2-(8-(4-fluoro-N-methylphenylsulfonamido)-6,7,8,9-tetrahydropyrido[4,3-b]indolizin-5-yl)acetic acid
Show/Hide
|
C20H20FN3O4S
|
1
|
| 1 |
Ki > 22000 nM
|
|
|
|
CP0426598
|
(R)-2-(2-chloro-8-(4-fluoro-N-methylphenylsulfonamido)-6,7,8,9-tetrahydropyrido[3,2-b]indolizin-5-yl)acetic acid
Show/Hide
|
C20H19ClFN3O4S
|
1
|
| 1 |
Ki > 27000 nM
|
|
|
|
CP0287896
|
2-((R)-8-((R)-2-(4-fluorophenyl)-N-methylpropanamido)-6,7,8,9-tetrahydropyrido[3,2-b]indolizin-5-yl)acetic acid
Show/Hide
|
C23H24FN3O3
|
1
|
| 1 |
Ki > 71000 nM
|
|
|
|
CP0478525
|
(R)-2-(8-(4-fluoro-N-methylphenylsulfonamido)-2-(4-fluorophenyl)-6,7,8,9-tetrahydropyrido[3,2-b]indolizin-5-yl)acetic acid
Show/Hide
|
C26H23F2N3O4S
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0378830
|
(R)-2-(7-(4-fluoro-N-methylphenylsulfonamido)-6,7,8,9-tetrahydropyrido[3,4-b]indolizin-10-yl)acetic acid
Show/Hide
|
C20H20FN3O4S
|
1
|
| 1 |
Ki > 6800 nM
|
|
|
|
CP0410061
|
(R)-2-(8-(1-(4-fluorophenyl)-N-methylcyclopropanecarboxamido)-6,7,8,9-tetrahydropyrido[3,2-b]indolizin-5-yl)acetic acid
Show/Hide
|
C24H24FN3O3
|
1
|
| 1 |
Ki > 6800 nM
|
|
|
|
CP0073515
|
(R)-2-(7-(4-fluoro-N-methylphenylsulfonamido)-6,7,8,9-tetrahydropyrido[2,3-b]indolizin-10-yl)acetic acid
Show/Hide
|
C20H20FN3O4S
|
1
|
| 1 |
Ki > 7000 nM
|
|
|
|
CP0379723
|
(R)-2-(8-(4-(4-fluorophenyl)-N-methyltetrahydro-2H-pyran-4-carboxamido)-6,7,8,9-tetrahydropyrido[3,2-b]indolizin-5-yl)acetic acid
Show/Hide
|
C26H28FN3O4
|
1
|
| 1 |
Ki > 7200 nM
|
|
|
|
CP0410062
|
2-((8R)-8-(1-(4-fluorophenyl)-N,2,2-trimethylcyclopropanecarboxamido)-6,7,8,9-tetrahydropyrido[3,2-b]indolizin-5-yl)acetic acid
Show/Hide
|
C26H28FN3O3
|
1
|
| 1 |
Ki > 7200 nM
|
|
|
|
CP0410064
|
(R)-2-(8-(1-(4-fluorophenyl)-N-methylcyclopentanecarboxamido)-6,7,8,9-tetrahydropyrido[3,2-b]indolizin-5-yl)acetic acid
Show/Hide
|
C26H28FN3O3
|
1
|
| 1 |
Ki > 7200 nM
|
|
|
|
CP0503601
|
(R)-2-(8-(1-(4-fluorophenyl)-N-methylcyclobutanecarboxamido)-6,7,8,9-tetrahydropyrido[3,2-b]indolizin-5-yl)acetic acid
Show/Hide
|
C25H26FN3O3
|
1
|
| 1 |
Ki > 7200 nM
|
|
|
