Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(2-(p-toluidino)-5-nitrophenylsulfonyl)-3-tert-butylurea
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 PubChem ID
CID: 5312142
SID: 15328505
Canonical SMILES
Cc1ccc(Nc2ccc(cc2S(=O)(=O)NC(=O)NC(C)(C)C)[N+]([O-])=O)cc1
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Compound Formula C18H22N4O5S
Compound Structure
Protein Name
 Protein Info 
Thromboxane A2 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
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Prostanoid receptor
Uniprot ID
P21731
Gene Name
TBXA2R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  2
1
IC50 = 0.78 nM
   TI
   LI
   LO
   TS
2
IC50 = 1.05 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  6
1
IC50 = 53 nM
   TI
   LI
   LO
   TS
2
IC50 = 53.1 nM
   TI
   LI
   LO
   TS
3
IC50 = 318.89 nM
   TI
   LI
   LO
   TS
4
IC50 = 319 nM
   TI
   LI
   LO
   TS
5
IC50 = 620 nM
   TI
   LI
   LO
   TS
6
IC50 = 700 nM
   TI
   LI
   LO
   TS