Brief Information of the Compound and Protein
Compound Name
1-cyclohexyl-3-[2-(4-methylphenoxy)-5-nitrophenyl]sulfonylurea
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PubChem ID
CID: 11683470
SID: 16787652
Canonical SMILES
Cc1ccc(Oc2ccc(cc2S(=O)(=O)NC(=O)NC2CCCCC2)[N+]([O-])=O)cc1
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Compound Formula C20H23N3O6S
Compound Structure
Protein Name
Thromboxane A2 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Prostanoid receptor
Uniprot ID
P21731
Gene Name
TBXA2R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7 Chlorocebus aethiops (Green monkey)  2
1
IC50 = 0.79 nM
   TI
   LI
   LO
   TS
2
IC50 = 1.52 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 70.15 nM
   TI
   LI
   LO
   TS
2
IC50 = 600.71 nM
   TI
   LI
   LO
   TS