| Compound ID |
Compound Name |
Compound Formula |
|
CP0192572
|
AVP
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|
C46H65N15O12S2
|
2
|
| 1 |
EC50 = 0.05 nM
|
|
|
| 2 |
Ki = 32 nM
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|
|
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CP0384534
|
(2S)-N-[(2R)-1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-10-propan-2-yl-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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|
C46H65N13O11S2
|
1
|
| 1 |
EC50 = 0.05 nM
|
|
|
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CP0384519
|
US10131692, Compound 10
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C42H60ClN11O8S2
|
1
|
| 1 |
EC50 = 0.07 nM
|
|
|
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CP0535808
|
(2S)-1-[(4S,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-10-propan-2-yl-13-(thiophen-2-ylmethyl)-1-thia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2R)-5-(diaminomethylideneamino)-1-hydroxypentan-2-yl]pyrrolidine-2-carboxamide
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|
C43H63N11O10S2
|
1
|
| 1 |
EC50 = 0.08 nM
|
|
|
|
CP0541818
|
US10131692, Compound 25
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|
C43H62ClN11O9S2
|
1
|
| 1 |
EC50 = 0.08 nM
|
|
|
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CP0384540
|
US10131692, Compound 8
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C44H62FN11O9S
|
1
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| 1 |
EC50 = 0.1 nM
|
|
|
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CP0477444
|
US10131692, Compound 33
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C44H63ClN12O9S3
|
1
|
| 1 |
EC50 = 0.1 nM
|
|
|
|
CP0517760
|
(2S)-1-[(3R,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-15-[(4-hydroxyphenyl)methyl]-5,8,11,14,17-pentaoxo-9-propan-2-yl-12-(thiophen-2-ylmethyl)-1-thia-4,7,10,13,16-pentazacycloicosane-3-carbonyl]-N-[(2S)-5-(diaminomethylideneamino)-1-hydroxypentan-2-yl]pyrrolidine-2-carboxamide
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|
C43H63N11O10S2
|
1
|
| 1 |
EC50 = 0.1 nM
|
|
|
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CP0850313
|
(2S,4R)-1-((4S,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-16-(4-chlorobenzyl)-10-isopropyl-6,9,12,15,18-pentaoxo-13-(thiophen-2-ylmethyl)-1-thia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)-N-((R)-1-(ethylamino)-5-guanidino-1-oxopentan-2-yl)-4-hydroxypyrrolidine-2-carboxamide
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|
C45H65ClN12O10S2
|
1
|
| 1 |
EC50 = 0.1 nM
|
|
|
|
CP0864311
|
(S)-1-((3R,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-15-(4-chlorobenzyl)-9-isopropyl-5,8,11,14,17-pentaoxo-12-(thiophen-2-ylmethyl)-1-thia-4,7,10,13,16-pentaazacycloicosane-3-carbonyl)-N-((R)-5-guanidino-1-hydroxypentan-2-yl)pyrrolidine-2-carboxamide
Show/Hide
|
C43H62ClN11O9S2
|
1
|
| 1 |
EC50 = 0.1 nM
|
|
|
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CP0468998
|
(4R)-3-[(4S,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-16-[(4-chlorophenyl)methyl]-6,9,12,15,18-pentaoxo-10-propan-2-yl-13-(thiophen-2-ylmethyl)-1-thia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2R)-5-(diaminomethylideneamino)-1-(ethylamino)-1-oxopentan-2-yl]-1,3-thiazolidine-4-carboxamide
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|
C44H63ClN12O9S3
|
1
|
| 1 |
EC50 = 0.11 nM
|
|
|
|
CP0548197
|
US10131692, Compound 40
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|
C41H58ClN11O8S3
|
1
|
| 1 |
EC50 = 0.12 nM
|
|
|
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CP0541819
|
(2S)-1-[(3R,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-15-[(4-chlorophenyl)methyl]-5,8,11,14,17-pentaoxo-9-propan-2-yl-12-(thiophen-2-ylmethyl)-1-thia-4,7,10,13,16-pentazacycloicosane-3-carbonyl]-N-[(2S)-5-(diaminomethylideneamino)-1-hydroxypentan-2-yl]pyrrolidine-2-carboxamide
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|
C43H62ClN11O9S2
|
1
|
| 1 |
EC50 = 0.14 nM
|
|
|
|
CP0411078
|
(4R)-3-[(3R,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-15-[(4-chlorophenyl)methyl]-5,8,11,14,17-pentaoxo-9-propan-2-yl-12-(thiophen-2-ylmethyl)-1-thia-4,7,10,13,16-pentazacycloicosane-3-carbonyl]-N-[(2R)-5-(diaminomethylideneamino)-1-oxo-1-(2-thiophen-2-ylethylamino)pentan-2-yl]-1,3-thiazolidine-4-carboxamide
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|
C48H65ClN12O9S4
|
1
|
| 1 |
EC50 = 0.17 nM
|
|
|
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CP0384536
|
(2S)-1-[(4S,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-16-[(4-chlorophenyl)methyl]-6,9,12,15,18-pentaoxo-10-propan-2-yl-13-(thiophen-2-ylmethyl)-1-thia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2R)-5-(diaminomethylideneamino)-1-(ethylamino)-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
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|
C45H65ClN12O9S2
|
1
|
| 1 |
EC50 = 0.19 nM
|
|
|
|
CP0483064
|
(2S)-N-(4-aminobutyl)-1-[(3R,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-15-[(4-hydroxyphenyl)methyl]-5,8,11,14,17-pentaoxo-9-propan-2-yl-12-(thiophen-2-ylmethyl)-1-thia-4,7,10,13,16-pentazacycloicosane-3-carbonyl]pyrrolidine-2-carboxamide
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|
C41H59N9O9S2
|
1
|
| 1 |
EC50 = 0.19 nM
|
|
|
|
CP0901651
|
(S)-1-((3R,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-15-(4-chlorobenzyl)-9-isopropyl-5,8,11,14,17-pentaoxo-12-(thiophen-2-ylmethyl)-1-thia-4,7,10,13,16-pentaazacycloicosane-3-carbonyl)-N-((R)-1-(benzylamino)-5-guanidino-1-oxopentan-2-yl)pyrrolidine-2-carboxamide
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|
C50H67ClN12O9S2
|
1
|
| 1 |
EC50 = 0.19 nM
|
|
|
|
CP0379479
|
(S)-1-((4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)-N-((R)-1-(2-amino-2-oxoethylamino)-5-guanidino-1-oxopentan-2-yl)pyrrolidine-2-carboxamide
Show/Hide
|
C46H64N14O12S2
|
1
|
| 1 |
EC50 = 0.2 nM
|
|
|
|
CP0384528
|
(2S,4R)-1-[(4S,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-16-[(4-chlorophenyl)methyl]-6,9,12,15,18-pentaoxo-10-propan-2-yl-13-(thiophen-2-ylmethyl)-1-thia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2R)-5-(diaminomethylideneamino)-1-(2-methylpropylamino)-1-oxopentan-2-yl]-4-hydroxypyrrolidine-2-carboxamide
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|
C47H69ClN12O10S2
|
1
|
| 1 |
EC50 = 0.2 nM
|
|
|
|
CP0477445
|
US10131692, Compound 35
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|
C45H65ClN12O9S3
|
1
|
| 1 |
EC50 = 0.21 nM
|
|
|
|
CP0850254
|
(S)-1-((3R,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-15-(4-chlorobenzyl)-9-isopropyl-5,8,11,14,17-pentaoxo-12-(thiophen-2-ylmethyl)-1-thia-4,7,10,13,16-pentaazacycloicosane-3-carbonyl)-N-((R)-1-(cyclopropylmethylamino)-5-guanidino-1-oxopentan-2-yl)pyrrolidine-2-carboxamide
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|
C47H67ClN12O9S2
|
1
|
| 1 |
EC50 = 0.21 nM
|
|
|
|
CP0384533
|
US10131692, Compound 5
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|
C47H69ClN12O9S2
|
1
|
| 1 |
EC50 = 0.22 nM
|
|
|
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CP0477442
|
US10131692, Compound 41
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|
C43H59ClFN11O8S2
|
1
|
| 1 |
EC50 = 0.22 nM
|
|
|
|
CP0905745
|
(S)-1-((4S,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-16-(4-chlorobenzyl)-10-isopropyl-6,9,12,15,18-pentaoxo-13-(thiophen-2-ylmethyl)-1-thia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)-N-((R)-5-guanidino-1-(isobutylamino)-1-oxopentan-2-yl)pyrrolidine-2-carboxamide
Show/Hide
|
C47H69ClN12O9S2
|
1
|
| 1 |
EC50 = 0.22 nM
|
|
|
|
CP0384525
|
US10131692, Compound 11
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C46H65ClN12O9S2
|
1
|
| 1 |
EC50 = 0.23 nM
|
|
|
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CP0909927
|
(2S,4R)-1-((3R,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-15-(4-chlorobenzyl)-9-isopropyl-5,8,11,14,17-pentaoxo-12-(thiophen-2-ylmethyl)-1-thia-4,7,10,13,16-pentaazacycloicosane-3-carbonyl)-N-((R)-5-guanidino-1-(isobutylamino)-1-oxopentan-2-yl)-4-hydroxypyrrolidine-2-carboxamide
Show/Hide
|
C47H69ClN12O10S2
|
1
|
| 1 |
EC50 = 0.23 nM
|
|
|
|
CP0909930
|
(S)-1-((3R,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-15-(4-chlorobenzyl)-9-isopropyl-5,8,11,14,17-pentaoxo-12-(thiophen-2-ylmethyl)-1-thia-4,7,10,13,16-pentaazacycloicosane-3-carbonyl)-N-((R)-1-(diethylamino)-5-guanidino-1-oxopentan-2-yl)pyrrolidine-2-carboxamide
Show/Hide
|
C47H69ClN12O9S2
|
1
|
| 1 |
EC50 = 0.25 nM
|
|
|
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CP0411077
|
US10131692, Compound 14
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|
C47H69ClN12O9S2
|
1
|
| 1 |
EC50 = 0.26 nM
|
|
|
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CP0483094
|
(2S)-1-[(3R,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-15-[(4-hydroxyphenyl)methyl]-5,8,11,14,17-pentaoxo-9-propan-2-yl-12-(thiophen-2-ylmethyl)-1-thia-4,7,10,13,16-pentazacycloicosane-3-carbonyl]-N-[(2R)-1-(benzylamino)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
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|
C50H68N12O10S2
|
1
|
| 1 |
EC50 = 0.26 nM
|
|
|
|
CP0527232
|
(2S)-1-[(3R,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-15-[(4-chlorophenyl)methyl]-5,8,11,14,17-pentaoxo-9-propan-2-yl-12-(thiophen-2-ylmethyl)-1-thia-4,7,10,13,16-pentazacycloicosane-3-carbonyl]-N-[(2R)-5-(diaminomethylideneamino)-1-(methylamino)-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
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|
C44H63ClN12O9S2
|
1
|
| 1 |
EC50 = 0.27 nM
|
|
|
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CP0850256
|
(S)-1-((4S,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-benzyl-16-(4-chlorobenzyl)-10-isopropyl-6,9,12,15,18-pentaoxo-1-thia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)-N-((R)-5-guanidino-1-(isobutylamino)-1-oxopentan-2-yl)pyrrolidine-2-carboxamide
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|
C49H71ClN12O9S
|
1
|
| 1 |
EC50 = 0.27 nM
|
|
|
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CP0384538
|
US10131692, Compound 19
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|
C47H69ClN12O9S2
|
1
|
| 1 |
EC50 = 0.29 nM
|
|
|
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CP0416666
|
US10131692, Compound 3
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|
C45H65ClN12O9S2
|
1
|
| 1 |
EC50 = 0.29 nM
|
|
|
|
CP0565251
|
(2S,4R)-1-[(3R,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-12-benzyl-15-[(4-chlorophenyl)methyl]-5,8,11,14,17-pentaoxo-9-propan-2-yl-1-thia-4,7,10,13,16-pentazacycloicosane-3-carbonyl]-N-[(2R)-5-(diaminomethylideneamino)-1-(ethylamino)-1-oxopentan-2-yl]-4-hydroxypyrrolidine-2-carboxamide
Show/Hide
|
C47H67ClN12O10S
|
1
|
| 1 |
EC50 = 0.29 nM
|
|
|
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CP0477441
|
(4R)-3-[(3R,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-15-[(4-chlorophenyl)methyl]-12-[(4-fluorophenyl)methyl]-5,8,11,14,17-pentaoxo-9-propan-2-yl-1-thia-4,7,10,13,16-pentazacycloicosane-3-carbonyl]-N-[(2R)-5-(diaminomethylideneamino)-1-oxo-1-(2-thiophen-2-ylethylamino)pentan-2-yl]-1,3-thiazolidine-4-carboxamide
Show/Hide
|
C50H66ClFN12O9S3
|
1
|
| 1 |
EC50 = 0.3 nM
|
|
|
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CP0477446
|
US10131692, Compound 7
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|
C44H61ClFN11O8S
|
1
|
| 1 |
EC50 = 0.31 nM
|
|
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CP0541817
|
US10131692, Compound 39
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|
C49H65ClN12O9S3
|
1
|
| 1 |
EC50 = 0.31 nM
|
|
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CP0559806
|
US10131692, Compound 30
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C44H63ClN12O9S3
|
1
|
| 1 |
EC50 = 0.32 nM
|
|
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CP0384517
|
US10131692, Compound 4
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|
C46H67ClN12O9S2
|
1
|
| 1 |
EC50 = 0.33 nM
|
|
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CP0384522
|
(2S)-1-[(3R,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-15-[(4-ethylphenyl)methyl]-5,8,11,14,17-pentaoxo-9-propan-2-yl-12-(thiophen-2-ylmethyl)-1-thia-4,7,10,13,16-pentazacycloicosane-3-carbonyl]-N-[(2R)-5-(diaminomethylideneamino)-1-hydroxypentan-2-yl]pyrrolidine-2-carboxamide
Show/Hide
|
C45H67N11O9S2
|
1
|
| 1 |
EC50 = 0.35 nM
|
|
|
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CP0850253
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(S)-1-((3R,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-15-(4-chlorobenzyl)-12-(4-fluorobenzyl)-9-isopropyl-5,8,11,14,17-pentaoxo-1-thia-4,7,10,13,16-pentaazacycloicosane-3-carbonyl)-N-((R)-5-guanidino-1-hydroxypentan-2-yl)pyrrolidine-2-carboxamide
Show/Hide
|
C45H63ClFN11O9S
|
1
|
| 1 |
EC50 = 0.35 nM
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CP0867627
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(S)-1-((4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-benzyl-16-(4-chlorobenzyl)-10-isopropyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)-N-((R)-1-(ethylamino)-5-guanidino-1-oxopentan-2-yl)pyrrolidine-2-carboxamide
Show/Hide
|
C46H65ClN12O9S2
|
1
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| 1 |
EC50 = 0.38 nM
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CP0384530
|
US10131692, Compound 2
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C44H65N11O9S2
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1
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| 1 |
EC50 = 0.39 nM
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CP0384523
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(2S)-1-[(3R,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-15-[(4-chlorophenyl)methyl]-5,8,11,14,17-pentaoxo-9-propan-2-yl-12-(thiophen-2-ylmethyl)-1-thia-4,7,10,13,16-pentazacycloicosane-3-carbonyl]-N-[(2R)-5-(diaminomethylideneamino)-1-oxo-1-(propan-2-ylamino)pentan-2-yl]pyrrolidine-2-carboxamide
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|
C46H67ClN12O9S2
|
1
|
| 1 |
EC50 = 0.45 nM
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CP0083253
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(5H,11H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10-yl)-[2-chloro-4-(3-methyl-pyrazol-1-yl)-phenyl]-methanone
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C23H19ClN4O
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1
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| 1 |
EC50 < 1 nM
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CP0386943
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(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-N-cyclobutyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C44H67N11O12S2
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1
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| 1 |
EC50 = 1.8 nM
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CP0191782
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1-(4-[3-(2,6-Difluorophenyl)ureidomethyl]-3-methylbenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepine
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C26H25F2N3O2
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2
|
| 1 |
EC50 = 2.1 nM
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| 2 |
Ki = 200 nM
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CP0418952
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(4R)-4-Hydroxy-1-(2-methyl-4-(2,3,4,5-tetrahydro-1-benzazepin-1-ylcarbonyl)benzylcarbamoyl)-L-proline-N,N-dimethylamide
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C27H34N4O4
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1
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| 1 |
EC50 = 2.3 nM
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CP0510042
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1-(2-Methyl-4-(2,3,4,5-tetrahydro-1-benzazepin-1-ylcarbonyl)benzylcarbamoyl)-L-proline-N,Ndimethylthioamide
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C27H34N4O2S
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1
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| 1 |
EC50 = 3.2 nM
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CP0374453
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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|
C43H65N11O12S2
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1
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| 1 |
EC50 = 3.5 nM
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CP0459759
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(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-N-cyclopropyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
Show/Hide
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C43H65N11O12S2
|
1
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| 1 |
EC50 = 4.2 nM
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CP0507981
|
(4R)-4-Ethoxy-1-(2-methyl-4-(2,3,4,5-tetrahydro-1-benzazepin-1-ylcarbonyl)benzyl-carbamoyl)-L-proline-N,N-dimethylamide
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|
C29H38N4O4
|
1
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| 1 |
EC50 = 4.3 nM
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CP0401893
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(4R)-4-Methoxy-1-(2-methyl-4-(2,3,4,5-tetrahydro-1-benzazepin-1-ylcarbonyl)benzylcarbamoyl)-L-proline-N,N-dimethylamide
Show/Hide
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C28H36N4O4
|
1
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| 1 |
EC50 = 4.7 nM
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CP0117986
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(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
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C43H66N12O12S2
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2
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| 1 |
EC50 = 7.3 nM
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| 2 |
Ki > 6000 nM
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CP0381555
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(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-N-(cyclopropylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C44H67N11O12S2
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1
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| 1 |
EC50 = 9.9 nM
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CP0515657
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1-(4-[3-(2,6-Difluorophenyl)ureidomethyl]-3-ethylbenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepine
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C27H27F2N3O2
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1
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| 1 |
EC50 = 10 nM
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CP0538045
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(4R)-4-Benzyloxy-1-(2-methyl-4-(2,3,4,5-tetrahydro-1-benzazepin-1-ylcarbonyl)benzylcarbamoyl)-L-proline-N,N-dimethylamide
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C34H40N4O4
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1
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| 1 |
EC50 = 10 nM
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CP0374491
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(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-N-cyclopentyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C45H69N11O12S2
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1
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| 1 |
EC50 = 11 nM
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CP0400333
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(4S,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-N-butyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1-thia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C45H71N11O12S
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1
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| 1 |
EC50 = 18 nM
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CP0542579
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4,4-Dimethoxy-1-(2-methyl-4-(2,3,4,5-tetrahydro-1-benzazepin-1-ylcarbonyl)benzyl-carbamoyl)-L-proline-N,N-dimethylamide
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C30H40N4O5
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1
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| 1 |
EC50 = 20 nM
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CP0363124
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1-(2-Methyl-4-(2,3,4,5-tetrahydro-1-benzazepin-1-ylcarbonyl)benzylcarbamoyl)-L-proline-N,N-dimethylamide
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C27H34N4O3
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2
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| 1 |
EC50 = 24 nM
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| 2 |
Ki = 2000 nM
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CP0541929
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1-(2-Methyl-4-(2,3,4,5-tetrahydro-1-benzazepin-1-ylcarbonyl)benzyl-carbamoyl)-4-oxo-L-proline-N,N-dimethylamide
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C27H32N4O4
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1
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| 1 |
EC50 = 27 nM
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CP0538059
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1-(4-[3-(2-Fluorophenyl)ureidomethyl]-3-methylbenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepine
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C26H26FN3O2
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1
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| 1 |
EC50 = 30 nM
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CP0381390
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(4S,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-N-(thiophen-2-ylmethyl)-1-thia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C46H67N11O12S2
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1
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| 1 |
EC50 = 30 nM
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CP0411518
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(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-N-[(3-methylphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C48H69N11O12S2
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1
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| 1 |
EC50 = 30 nM
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CP0379415
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(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-N-benzyl-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C47H67N11O12S2
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1
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| 1 |
EC50 = 34 nM
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CP0374490
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(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-N-butyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C44H69N11O12S2
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1
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| 1 |
EC50 = 35 nM
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CP0381388
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(4S,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-N-benzyl-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1-thia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C48H69N11O12S
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1
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| 1 |
EC50 = 36 nM
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CP0538715
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1-(4-[N-(2-Methoxy-2-oxoethylcarbamoyl]aminomethyl]-3-methylbenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepine
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C23H27N3O4
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1
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| 1 |
EC50 = 37 nM
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CP0517021
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1-(2-Chloro-4-[3-(2,6-difluorophenyl)ureidomethyl]benzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepine
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C25H22ClF2N3O2
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1
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| 1 |
EC50 = 40 nM
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CP0379414
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(2S,4S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(3R,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-9-(3-amino-3-oxopropyl)-12-[(2S)-butan-2-yl]-15-[(4-ethoxyphenyl)methyl]-5,8,11,14,17-pentaoxo-1-thia-4,7,10,13,16-pentazacycloicosane-3-carbonyl]-4-hydroxypyrrolidine-2-carboxamide
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C46H71N11O13S
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1
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| 1 |
EC50 = 40 nM
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CP0503496
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(4R)-4-tert-Butoxyoxy-1-(2-methyl-4-(2,3,4,5-tetrahydro-1-benzazepin-1-ylcarbonyl)benzylcarbamoyl)-L-proline-N,N-dimethylamide
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C31H42N4O4
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1
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| 1 |
EC50 = 46 nM
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CP0418950
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1-(4-[3-(2,6-Difluorophenyl)ureidomethyl]benzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepine
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C25H23F2N3O2
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1
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| 1 |
EC50 = 47 nM
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CP0425948
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(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-N-(2-pyridin-4-ylethyl)-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C47H68N12O12S2
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1
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| 1 |
EC50 = 47 nM
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CP0503497
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4,4-Difluoro-1-(2-methyl-4-(2,3,4,5-tetrahydro-1-benzazepin-1-ylcarbonyl)benzyl-carbamoyl)-Lproline-N,N-dimethylamide
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C28H34F2N4O3
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1
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| 1 |
EC50 = 50 nM
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CP0480508
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(4S,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-N-(2-methoxyethyl)-6,9,12,15,18-pentaoxo-1-thia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C44H69N11O13S
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1
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| 1 |
EC50 = 52 nM
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CP0379965
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(4S,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-N-[(3-methylphenyl)methyl]-6,9,12,15,18-pentaoxo-1-thia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C49H71N11O12S
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1
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| 1 |
EC50 = 55 nM
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CP0379490
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(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-N-(thiophen-2-ylmethyl)-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C45H65N11O12S3
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1
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| 1 |
EC50 = 57 nM
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CP0400335
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(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-N-cyclohexyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C46H71N11O12S2
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1
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| 1 |
EC50 = 57 nM
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CP0510041
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1-(4-[N-(2-dimethylamino-2-oxoethylcarbamoyl)aminomethyl]-3-methylbenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepine
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C24H30N4O3
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1
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| 1 |
EC50 = 58 nM
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CP0374449
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(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-N-(furan-2-ylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C45H65N11O13S2
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1
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| 1 |
EC50 = 62 nM
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CP0379489
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(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-N-(2-phenylethyl)-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C48H69N11O12S2
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1
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| 1 |
EC50 = 66 nM
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CP0379484
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(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-N-[(2-methylphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C48H69N11O12S2
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1
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| 1 |
EC50 = 68 nM
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CP0379491
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(3R,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-9-(3-amino-3-oxopropyl)-12-[(2S)-butan-2-yl]-15-[(4-hydroxyphenyl)methyl]-N-(2-methoxyethyl)-5,8,11,14,17-pentaoxo-1-thia-4,7,10,13,16-pentazacycloicosane-3-carboxamide
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C44H69N11O13S
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1
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| 1 |
EC50 = 70 nM
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CP0379420
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(3R,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-9-(3-amino-3-oxopropyl)-12-[(2S)-butan-2-yl]-N-butyl-15-[(4-hydroxyphenyl)methyl]-5,8,11,14,17-pentaoxo-1-thia-4,7,10,13,16-pentazacycloicosane-3-carboxamide
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C45H71N11O12S
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1
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| 1 |
EC50 = 73 nM
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CP0379963
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(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-N-pentyl-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C45H71N11O12S2
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1
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| 1 |
EC50 = 77 nM
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CP0379486
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(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-N-[(4-methoxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C48H69N11O13S2
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1
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| 1 |
EC50 = 78 nM
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CP0386875
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(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-N-(2-methoxyethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C43H67N11O13S2
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1
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| 1 |
EC50 = 80 nM
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CP0507976
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1-(4-[3-(2,6-Difluorophenyl)ureidomethyl]-3,5-dimethylbenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepine
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C27H27F2N3O2
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1
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| 1 |
EC50 = 82 nM
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CP0379229
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(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-N-[(4-fluorophenyl)methyl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C47H66FN11O12S2
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1
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| 1 |
EC50 = 82 nM
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CP0503498
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1-(4-(6,7-Dihydro-5H-dibenzo[b,d]azepin-5-ylcarbonyl)-2-methylbenzylcarbamoyl)-L-proline-N,N-dimethylamide
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C31H34N4O3
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1
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| 1 |
EC50 = 84 nM
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CP0379976
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(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-N-[(4-methylphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C48H69N11O12S2
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1
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| 1 |
EC50 = 84 nM
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CP0418736
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(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-N-(2-thiophen-2-ylethyl)-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C46H67N11O12S3
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1
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| 1 |
EC50 = 86 nM
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CP0503495
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1-(2-Methyl-4-(2,3,4,5-tetrahydro-1-benzazepin-1-ylcarbonyl)benzylcarbamoyl)-L-prolinemethyl ester
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C26H31N3O4
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1
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| 1 |
EC50 = 100 nM
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CP0507979
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1-(4-[N-(2-Pyrrolidin-1-yl-2-oxoethylcarbamoyl]aminomethyl]-3-methylbenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepine
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C26H32N4O3
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1
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| 1 |
EC50 = 100 nM
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CP0379228
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(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-N-(3-hydroxypropyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C43H67N11O13S2
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1
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| 1 |
EC50 = 100 nM
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CP0379406
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(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-N-hexyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C46H73N11O12S2
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1
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| 1 |
EC50 = 100 nM
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CP0379412
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(4S,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-N-(2-phenylethyl)-1-thia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C49H71N11O12S
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1
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| 1 |
EC50 = 100 nM
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CP0478988
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1-(4-[3-(2,6-Difluorophenyl)ureidomethyl]-2-methoxybenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepine
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C26H25F2N3O3
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1
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| 1 |
EC50 = 110 nM
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CP0386873
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(3R,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-9-(3-amino-3-oxopropyl)-12-[(2S)-butan-2-yl]-15-[(4-hydroxyphenyl)methyl]-5,8,11,14,17-pentaoxo-N-pentyl-1-thia-4,7,10,13,16-pentazacycloicosane-3-carboxamide
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C46H73N11O12S
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1
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| 1 |
EC50 = 110 nM
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CP0452526
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1-(4-[N-(2-tert-butyloxy-2-oxoethylcarbamoyl)aminomethyl]-3-methylbenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepine
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C26H33N3O4
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1
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| 1 |
EC50 = 120 nM
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CP0510043
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1-(4-(10,11-Dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-10-ylcarbonyl)-2-methylbenzylcarbamoyl)-L-proline-N,N-dimethylamide
Show/Hide
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C29H33N5O3
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1
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| 1 |
EC50 = 120 nM
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CP0503494
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1-(4-[3-Phenylureidomethyl]-3-methylbenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepine
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C26H27N3O2
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1
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| 1 |
EC50 = 130 nM
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CP0452525
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1-(4-[N-(2-iso-propyloxy-2-oxoethylcarbamoyl)aminomethyl]-3-methylbenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepine
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C25H31N3O4
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1
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| 1 |
EC50 = 140 nM
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CP0517553
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1-(4-[N-(2-Ethoxy-2-oxoethylcarbamoyl)aminomethyl]-3-methylbenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepine
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C24H29N3O4
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1
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| 1 |
EC50 = 140 nM
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CP0538060
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1-(3-Methyl-4-[3-(2-oxo-1,2-dihydropyrid-3-yl)ureidomethyllbenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepine
Show/Hide
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C25H26N4O3
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1
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| 1 |
EC50 = 140 nM
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CP0548966
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1-(4-(6,7-Dihydro-5H-pyrrolo[1,2-a][1,5]benzodiazepine-5-ylcarbonyl)-2-methylbenzylcarbamoyl)-L-proline-N,N-dimethylamide
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C29H33N5O3
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1
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| 1 |
EC50 = 140 nM
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CP0379419
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(3R,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-9-(3-amino-3-oxopropyl)-N-benzyl-12-[(2S)-butan-2-yl]-15-[(4-hydroxyphenyl)methyl]-5,8,11,14,17-pentaoxo-1-thia-4,7,10,13,16-pentazacycloicosane-3-carboxamide
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C48H69N11O12S
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1
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| 1 |
EC50 = 140 nM
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CP0379979
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(4S,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-N-[(4-fluorophenyl)methyl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1-thia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C48H68FN11O12S
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1
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| 1 |
EC50 = 140 nM
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CP0478989
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1-(4-[N-(2-Piperidin-1-yl-2-oxoethylcarbamoyl]aminomethyl]-3-methylbenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepine
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C27H34N4O3
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1
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| 1 |
EC50 = 150 nM
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CP0379492
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(4S,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-N-(3-hydroxypropyl)-6,9,12,15,18-pentaoxo-1-thia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C44H69N11O13S
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1
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| 1 |
EC50 = 150 nM
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CP0386942
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(3R,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-9-(3-amino-3-oxopropyl)-12-[(2S)-butan-2-yl]-15-[(4-hydroxyphenyl)methyl]-5,8,11,14,17-pentaoxo-N-(2-phenylethyl)-1-thia-4,7,10,13,16-pentazacycloicosane-3-carboxamide
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C49H71N11O12S
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1
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| 1 |
EC50 = 160 nM
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CP0386874
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CHEBI:59204
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C45H69N11O12S
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1
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| 1 |
EC50 = 170 nM
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CP0389135
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(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-N-(pyridin-3-ylmethyl)-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C46H66N12O12S2
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1
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| 1 |
EC50 = 170 nM
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CP0503493
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1-(4-[3-(2,6-Difluorophenyl)ureidomethyl]-2-fluorobenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepine
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C25H22F3N3O2
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1
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| 1 |
EC50 = 180 nM
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CP0507977
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1-(4-[N-(Carboxymethylcarbamoyl)aminomethyl]-3-methylbenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepine
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C22H25N3O4
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1
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| 1 |
EC50 = 180 nM
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CP0379243
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(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-N-(2-pyridin-2-ylethyl)-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C47H68N12O12S2
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1
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| 1 |
EC50 = 180 nM
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CP0379964
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(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-N-(pyridin-2-ylmethyl)-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
Show/Hide
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C46H66N12O12S2
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1
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| 1 |
EC50 = 180 nM
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CP0507978
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1-(4-[N-(2-Amino-2-oxoethylcarbamoyl)aminomethyl]-3-methylbenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepine
Show/Hide
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C22H26N4O3
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1
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| 1 |
EC50 = 210 nM
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CP0379295
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(3R,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-9-(3-amino-3-oxopropyl)-12-[(2S)-butan-2-yl]-15-[(4-hydroxyphenyl)methyl]-N-[(3-methylphenyl)methyl]-5,8,11,14,17-pentaoxo-1-thia-4,7,10,13,16-pentazacycloicosane-3-carboxamide
Show/Hide
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C49H71N11O12S
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1
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| 1 |
EC50 = 210 nM
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CP0401894
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1-(2-Methyl-4-(5-methyl-2,3,4,5-tetrahydro-1-benzazepin-1-ylcarbonyl)-benzylcarbamoyl)-Lproline-N,N-dimethylamide
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C28H36N4O3
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1
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| 1 |
EC50 = 220 nM
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CP0507982
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1-(4-(5-Hydroxy-2,3,4,5-tetrahydro-1-benzazepin-1-ylcarbonyl)-2-methylbenzylcarbamoyl)-L-proline-N,N-dimethylamide
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C27H34N4O4
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1
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| 1 |
EC50 = 230 nM
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CP0374493
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(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-N-(oxolan-2-ylmethyl)-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C45H69N11O13S2
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1
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| 1 |
EC50 = 230 nM
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CP0379493
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(3R,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-9-(3-amino-3-oxopropyl)-12-[(2S)-butan-2-yl]-15-[(4-hydroxyphenyl)methyl]-5,8,11,14,17-pentaoxo-N-(thiophen-2-ylmethyl)-1-thia-4,7,10,13,16-pentazacycloicosane-3-carboxamide
Show/Hide
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C46H67N11O12S2
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1
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| 1 |
EC50 = 250 nM
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CP0541928
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1-(4-[N-(2-Benzylamino-2-oxoethylcarbamoyl]aminomethyl]-3-methylbenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepine
Show/Hide
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C29H32N4O3
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1
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| 1 |
EC50 = 270 nM
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CP0379418
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(3R,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-9-(3-amino-3-oxopropyl)-12-[(2S)-butan-2-yl]-N-[(4-fluorophenyl)methyl]-15-[(4-hydroxyphenyl)methyl]-5,8,11,14,17-pentaoxo-1-thia-4,7,10,13,16-pentazacycloicosane-3-carboxamide
Show/Hide
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C48H68FN11O12S
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1
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| 1 |
EC50 = 330 nM
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CP0417406
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1-(2-Methyl-4-(2,3,4,5-tetrahydro-1-benzazepin-1-ylcarbonyl)benzylcarbamoyl)-L-proline-N,Ndiethylamide
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C29H38N4O3
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1
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| 1 |
EC50 = 350 nM
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CP0535545
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1-(2-Methyl-4-(2,3,4,5-tetrahydro-1-benzazepin-1-ylcarbonyl)benzylcarbamoyl)-D-proline-N,Ndimethylamide
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C27H34N4O3
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1
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| 1 |
EC50 = 380 nM
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CP0379977
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(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-N-(pyridin-4-ylmethyl)-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
Show/Hide
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C46H66N12O12S2
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1
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| 1 |
EC50 = 380 nM
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CP0493309
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1-(2-Methyl-4-(2,3,4,5-tetrahydro-1-benzazepin-1-ylcarbonyl)benzylcarbamoyl)-L-proline tertbutylester
Show/Hide
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C29H37N3O4
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1
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| 1 |
EC50 = 390 nM
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CP0374451
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(3R,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-9-(3-amino-3-oxopropyl)-12-[(2S)-butan-2-yl]-15-[(4-methoxyphenyl)methyl]-5,8,11,14,17-pentaoxo-1-thia-4,7,10,13,16-pentazacycloicosane-3-carboxamide
Show/Hide
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C42H65N11O12S
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1
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| 1 |
EC50 = 450 nM
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CP0410443
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(2S,4S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(3R,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-9-(3-amino-3-oxopropyl)-12-[(2S)-butan-2-yl]-15-[(4-ethoxyphenyl)methyl]-5,8,11,14,17-pentaoxo-1-thia-4,7,10,13,16-pentazacycloicosane-3-carbonyl]-4-methoxypyrrolidine-2-carboxamide
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C47H73N11O13S
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1
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| 1 |
EC50 = 450 nM
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CP0374494
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(3R,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-9-(3-amino-3-oxopropyl)-12-[(2S)-butan-2-yl]-15-[(4-hydroxyphenyl)methyl]-N-(3-hydroxypropyl)-5,8,11,14,17-pentaoxo-1-thia-4,7,10,13,16-pentazacycloicosane-3-carboxamide
Show/Hide
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C44H69N11O13S
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1
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| 1 |
EC50 = 500 nM
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CP0381414
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(2S,4R)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(3R,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-9-(3-amino-3-oxopropyl)-12-[(2S)-butan-2-yl]-15-[(4-methoxyphenyl)methyl]-5,8,11,14,17-pentaoxo-1-thia-4,7,10,13,16-pentazacycloicosane-3-carbonyl]-4-methylsulfanylpyrrolidine-2-carboxamide
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C46H71N11O12S2
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1
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| 1 |
EC50 = 670 nM
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CP0401892
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1-(2-Methyl-4-(2,3,4,5-tetrahydro-1-benzazepin-1-ylcarbonyl)benzylcarbamoyl)-L-proline
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C25H29N3O4
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1
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| 1 |
EC50 = 680 nM
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CP0379417
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(2S,4R)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(3R,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-9-(3-amino-3-oxopropyl)-12-[(2S)-butan-2-yl]-15-[(4-methoxyphenyl)methyl]-5,8,11,14,17-pentaoxo-1-thia-4,7,10,13,16-pentazacycloicosane-3-carbonyl]-4-methoxypyrrolidine-2-carboxamide
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C46H71N11O13S
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1
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| 1 |
EC50 = 690 nM
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CP0374485
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(4S,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-N,16-dibenzyl-13-[(2S)-butan-2-yl]-6,9,12,15,18-pentaoxo-1-thia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
Show/Hide
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C48H69N11O11S
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1
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| 1 |
EC50 = 720 nM
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CP0541927
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1-(4-[N-(2-Benzyloxy-2-oxoethylcarbamoyl]aminomethyl]-3-methylbenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepine
Show/Hide
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C29H31N3O4
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1
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| 1 |
EC50 = 730 nM
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CP0386854
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(4S,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-16-benzyl-13-[(2S)-butan-2-yl]-6,9,12,15,18-pentaoxo-N-(thiophen-2-ylmethyl)-1-thia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
Show/Hide
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C46H67N11O11S2
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1
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| 1 |
EC50 = 760 nM
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CP0515659
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1-(4-[N-(2-Phenoxy-2-oxoethylcarbamoyl]aminomethyl]-3-methylbenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepine
Show/Hide
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C28H29N3O4
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1
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| 1 |
EC50 = 820 nM
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CP0507980
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1-(2-Methyl-4-(2,3,4,5-tetrahydro-1-benzazepin-1-ylcarbonyl)benzylcarbamoyl)-L-proline isopropylester
Show/Hide
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C28H35N3O4
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1
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| 1 |
EC50 = 950 nM
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CP0507983
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1-(2-Methyl-4-(2,3,4,5-tetrahydro-1,5-benzoxazepin-5-ylcarbonyl)benzylcarbamoyl)-L-proline-N,N-dimethylamide
Show/Hide
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C26H32N4O4
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1
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| 1 |
EC50 = 1000 nM
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CP0379978
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(4S,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-16-benzyl-13-[(2S)-butan-2-yl]-6,9,12,15,18-pentaoxo-N-pentyl-1-thia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
Show/Hide
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C46H73N11O11S
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1
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| 1 |
EC50 = 1000 nM
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CP0425942
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(3R,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-9-(3-amino-3-oxopropyl)-15-benzyl-12-[(2S)-butan-2-yl]-N-(2-methoxyethyl)-5,8,11,14,17-pentaoxo-1-thia-4,7,10,13,16-pentazacycloicosane-3-carboxamide
Show/Hide
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C44H69N11O12S
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1
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| 1 |
EC50 = 1100 nM
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CP0374495
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(4S,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-16-benzyl-13-[(2S)-butan-2-yl]-N-butyl-6,9,12,15,18-pentaoxo-1-thia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
Show/Hide
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C45H71N11O11S
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1
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| 1 |
EC50 = 1200 nM
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CP0379421
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(4S,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-16-benzyl-13-[(2S)-butan-2-yl]-N-(2-methoxyethyl)-6,9,12,15,18-pentaoxo-1-thia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
Show/Hide
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C44H69N11O12S
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1
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| 1 |
EC50 = 1300 nM
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CP0379240
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(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-N-(2-morpholin-4-ylethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C46H72N12O13S2
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1
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| 1 |
EC50 = 1400 nM
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CP0379296
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(4S,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-16-benzyl-13-[(2S)-butan-2-yl]-N-[(4-fluorophenyl)methyl]-6,9,12,15,18-pentaoxo-1-thia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C48H68FN11O11S
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1
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| 1 |
EC50 = 1400 nM
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CP0410445
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(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-N-(2-pyrrolidin-2-ylethyl)-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C46H72N12O12S2
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1
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| 1 |
EC50 = 1400 nM
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CP0374487
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(4S,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-16-benzyl-13-[(2S)-butan-2-yl]-N-[(3-methylphenyl)methyl]-6,9,12,15,18-pentaoxo-1-thia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C49H71N11O11S
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1
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| 1 |
EC50 = 1600 nM
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CP0493310
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1-(4-(5,5-Difluoro-2,3,4,5-tetrahydro-1-benzazepin-1-ylcarbonyl)-2-methylbenzylcarbamoyl)-Lproline-N,N-dimethylamide
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C27H32F2N4O3
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1
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| 1 |
EC50 = 1700 nM
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CP0410446
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(3R,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-9-(3-amino-3-oxopropyl)-15-benzyl-12-[(2S)-butan-2-yl]-N-butyl-5,8,11,14,17-pentaoxo-1-thia-4,7,10,13,16-pentazacycloicosane-3-carboxamide
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C45H71N11O11S
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1
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| 1 |
EC50 = 2000 nM
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CP0374452
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(4S,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-N-pentyl-1-thia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C46H73N11O12S
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1
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| 1 |
EC50 = 2100 nM
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CP0381413
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(4S,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-16-benzyl-13-[(2S)-butan-2-yl]-N-(3-hydroxypropyl)-6,9,12,15,18-pentaoxo-1-thia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C44H69N11O12S
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1
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| 1 |
EC50 = 2600 nM
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CP0379284
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(4S,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-16-benzyl-13-[(2S)-butan-2-yl]-6,9,12,15,18-pentaoxo-N-(2-phenylethyl)-1-thia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C49H71N11O11S
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1
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| 1 |
EC50 = 3000 nM
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CP0374995
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(2S)-N-[(2S)-4-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxobutan-2-yl]-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7,10-bis(2-amino-2-oxoethyl)-13-[(2S)-butan-2-yl]-16-(cyclohexylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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C40H67N13O11S2
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1
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| 1 |
EC50 > 10000 nM
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CP0375101
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(2S)-N-[(2S)-4-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxobutan-2-yl]-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7,10-bis(2-amino-2-oxoethyl)-13-[(2S)-butan-2-yl]-6,9,12,15,18-pentaoxo-16-(thiophen-3-ylmethyl)-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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C38H59N13O11S3
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1
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| 1 |
EC50 > 10000 nM
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CP0375555
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(2S)-N-[(2S)-4-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxobutan-2-yl]-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-(1-benzothiophen-3-ylmethyl)-13-[(2S)-butan-2-yl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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C43H63N13O11S3
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1
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| 1 |
EC50 > 10000 nM
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CP0376024
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(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7,10-bis(2-amino-2-oxoethyl)-13-[(2S)-butan-2-yl]-6,9,12,15,18-pentaoxo-16-(thiophen-2-ylmethyl)-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-5-(propan-2-ylamino)pentan-2-yl]pyrrolidine-2-carboxamide
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C42H67N13O11S3
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1
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| 1 |
EC50 > 10000 nM
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CP0376025
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(2S)-N-[(2S)-4-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxobutan-2-yl]-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-6,9,12,15,18-pentaoxo-16-(pyridin-3-ylmethyl)-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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C40H62N14O11S2
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1
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| 1 |
EC50 > 10000 nM
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CP0388466
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(2S)-N-[(2S)-4-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxobutan-2-yl]-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-methyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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C35H59N13O11S2
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1
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| 1 |
EC50 > 10000 nM
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CP0396899
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(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7,10-bis(2-amino-2-oxoethyl)-13-[(2S)-butan-2-yl]-16-(furan-2-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-5-(propan-2-ylamino)pentan-2-yl]pyrrolidine-2-carboxamide
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C42H67N13O12S2
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1
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| 1 |
EC50 > 10000 nM
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CP0436229
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(2S)-N-[(2S)-4-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxobutan-2-yl]-1-[(7R,12R,15S,18S,21S)-7-amino-15,18-bis(2-amino-2-oxoethyl)-21-[(2S)-butan-2-yl]-6,14,17,20,23-pentaoxo-9,10-dithia-5,13,16,19,22-pentazaspiro[3.19]tricosane-12-carbonyl]pyrrolidine-2-carboxamide
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C36H59N13O11S2
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1
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| 1 |
EC50 > 10000 nM
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CP0436271
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(2S)-N-[(2S)-5-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-16-benzyl-13-[(2S)-butan-2-yl]-10-[2-[2-(2-hydroxyethoxy)ethylamino]-2-oxoethyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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C45H71N13O13S2
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1
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| 1 |
EC50 > 10000 nM
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CP0438004
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(2S)-N-[(2S)-4-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxobutan-2-yl]-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7,10-bis(2-amino-2-oxoethyl)-16-benzyl-13-[(2S)-butan-2-yl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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C40H61N13O11S2
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1
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| 1 |
EC50 > 10000 nM
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CP0449267
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(2S)-N-[(2S)-5-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7,10-bis(2-amino-2-oxoethyl)-13-[(2S)-butan-2-yl]-6,9,12,15,18-pentaoxo-16-(thiophen-3-ylmethyl)-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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C39H61N13O11S3
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1
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| 1 |
EC50 > 10000 nM
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CP0449270
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(2S)-N-[(2S)-5-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-16-benzyl-13-[(2S)-butan-2-yl]-10-[2-(methylamino)-2-oxoethyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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C42H65N13O11S2
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1
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| 1 |
EC50 > 10000 nM
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CP0452427
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(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7,10-bis(2-amino-2-oxoethyl)-16-benzyl-13-[(2S)-butan-2-yl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-5-(methylamino)-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
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C42H65N13O11S2
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1
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| 1 |
EC50 > 10000 nM
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CP0452428
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(2S)-N-[(2S)-5-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxopentan-2-yl]-1-[(7R,12R,15S,18S,21S)-7-amino-15,18-bis(2-amino-2-oxoethyl)-21-[(2S)-butan-2-yl]-6,14,17,20,23-pentaoxo-9,10-dithia-5,13,16,19,22-pentazaspiro[3.19]tricosane-12-carbonyl]pyrrolidine-2-carboxamide
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C37H61N13O11S2
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1
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| 1 |
EC50 > 10000 nM
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CP0452434
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(2S)-N-[(2S)-5-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7,10-bis(2-amino-2-oxoethyl)-13-[(2S)-butan-2-yl]-16-(furan-2-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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C39H61N13O12S2
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1
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| 1 |
EC50 > 10000 nM
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CP0452435
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(2S)-N-[(2S)-4-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxobutan-2-yl]-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7,10-bis(2-amino-2-oxoethyl)-13-[(2S)-butan-2-yl]-16-(cyclopentylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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C39H65N13O11S2
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1
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| 1 |
EC50 > 10000 nM
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CP0452487
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(2S)-N-[(2S)-5-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-16-benzyl-13-[(2S)-butan-2-yl]-10-[2-(dimethylamino)-2-oxoethyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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C43H67N13O11S2
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1
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| 1 |
EC50 > 10000 nM
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CP0455215
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(2S)-N-[(2S)-5-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-16-benzyl-13-[(2S)-butan-2-yl]-10-[2-(3-hydroxypropylamino)-2-oxoethyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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C44H69N13O12S2
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1
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| 1 |
EC50 > 10000 nM
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CP0455216
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(2S)-N-[(2S)-5-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-16-benzyl-13-[(2S)-butan-2-yl]-10-[2-(1,3-dihydroxypropan-2-ylamino)-2-oxoethyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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C44H69N13O13S2
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1
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| 1 |
EC50 > 10000 nM
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CP0455217
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(2S)-N-[(2S)-5-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7,10-bis(2-amino-2-oxoethyl)-13-[(2S)-butan-2-yl]-6,9,12,15,18-pentaoxo-16-(thiophen-2-ylmethyl)-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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C39H61N13O11S3
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1
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| 1 |
EC50 > 10000 nM
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CP0455373
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(2S)-N-[(2S)-5-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7,10-bis(2-amino-2-oxoethyl)-16-benzyl-13-[(2S)-butan-2-yl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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C41H63N13O11S2
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1
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| 1 |
EC50 > 10000 nM
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CP0455375
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(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7,10-bis(2-amino-2-oxoethyl)-16-benzyl-13-[(2S)-butan-2-yl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-5-(ethylamino)-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
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C43H67N13O11S2
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1
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| 1 |
EC50 > 10000 nM
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CP0458828
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(2S)-N-[(2S)-5-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7,10-bis(2-amino-2-oxoethyl)-13-[(2S)-butan-2-yl]-16-(cyclopentylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
Show/Hide
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C40H67N13O11S2
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1
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| 1 |
EC50 > 10000 nM
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CP0458829
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(2S)-N-[(2S)-5-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-16-benzyl-13-[(2S)-butan-2-yl]-10-[2-(2-hydroxyethylamino)-2-oxoethyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
Show/Hide
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C43H67N13O12S2
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1
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| 1 |
EC50 > 10000 nM
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CP0458831
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(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7,10-bis(2-amino-2-oxoethyl)-16-benzyl-13-[(2S)-butan-2-yl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-5-(propylamino)pentan-2-yl]pyrrolidine-2-carboxamide
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C44H69N13O11S2
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1
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| 1 |
EC50 > 10000 nM
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CP0458832
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(2S)-N-[(2S)-4-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxobutan-2-yl]-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7,10-bis(2-amino-2-oxoethyl)-13-[(2S)-butan-2-yl]-6,9,12,15,18-pentaoxo-16-(thiophen-2-ylmethyl)-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
Show/Hide
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C38H59N13O11S3
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1
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| 1 |
EC50 > 10000 nM
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CP0465978
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(2S)-N-[(2S)-4-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxobutan-2-yl]-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7,10-bis(2-amino-2-oxoethyl)-13-[(2S)-butan-2-yl]-16-(furan-2-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
Show/Hide
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C38H59N13O12S2
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1
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| 1 |
EC50 > 10000 nM
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CP0466471
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(2S)-N-[(2S)-5-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7,10-bis(2-amino-2-oxoethyl)-13-[(2S)-butan-2-yl]-16-(cyclohexylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
Show/Hide
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C41H69N13O11S2
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1
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| 1 |
EC50 > 10000 nM
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CP0466472
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(2S)-N-[(2S)-5-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-16-benzyl-13-[(2S)-butan-2-yl]-10-[2-(ethylamino)-2-oxoethyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
Show/Hide
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C43H67N13O11S2
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1
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| 1 |
EC50 > 10000 nM
|
|
|
|
CP0472412
|
(2S)-N-[(2S)-5-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-16-benzyl-13-[(2S)-butan-2-yl]-10-[2-(2-hydroxypropylamino)-2-oxoethyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
Show/Hide
|
C44H69N13O12S2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0493967
|
(2S)-N-[(2S)-4-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxobutan-2-yl]-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-(1H-imidazol-5-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
Show/Hide
|
C38H61N15O11S2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0040044
|
3-chloro-4-(10,11-dihydro-5H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10-ylcarbonyl)-1-(5-fluoro-2-methylphenylcarboxamido)benzene
Show/Hide
|
C27H21ClFN3O2
|
3
|
| 1 |
IC50 = 5 nM
|
|
|
| 2 |
IC50 = 91 nM
|
|
|
| 3 |
Ki = 90 nM
|
|
|
|
CP0357770
|
Biphenyl-2-carboxylic acid [4-(2-oxo-1,2,2a,3,4,5-hexahydro-azepino[4,3,2-cd]indole-6-carbonyl)-phenyl]-amide
Show/Hide
|
C31H25N3O3
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0464288
|
(4R)-N-[2-(dimethylamino)ethyl]-1-({4-[(2-phenylbenzene)amido]phenyl}carbonyl)-1,2,3,5-tetrahydrospiro[1-benzazepine-4,1'-cyclopentan]-2'-ene-3'-carboxamide
Show/Hide
|
C39H40N4O3
|
2
|
| 1 |
IC50 = 8 nM
|
|
|
| 2 |
IC50 = 36 nM
|
|
|
|
CP0042892
|
3'N-(2-hexahydro-1-pyridinylethyl)-1-[4-(5-fluoro-2-methylphenylcarboxamido)benzoyl]spiro[2,3,4,5-tetrahydro-1H-benzo[b]azepine-4,1'-(2'-cyclopentene)]-3'-carboxamide
Show/Hide
|
C37H41FN4O3
|
2
|
| 1 |
IC50 = 9 nM
|
|
|
| 2 |
IC50 = 48 nM
|
|
|
|
CP0511186
|
4'-Methyl-biphenyl-2-carboxylic acid [4-(1,3,4,5-tetrahydro-azepino[4,3,2-cd]indole-6-carbonyl)-phenyl]-amide
Show/Hide
|
C32H27N3O2
|
2
|
| 1 |
IC50 = 11 nM
|
|
|
| 2 |
IC50 = 70 nM
|
|
|
|
CP0501743
|
(4R)-1-({4-[(2-chloro-5-fluorobenzene)amido]-3-methoxyphenyl}carbonyl)-N-sulfamoyl-1,2,3,5-tetrahydrospiro[1-benzazepine-4,1'-cyclopentan]-2'-ene-3'-carboxamide
Show/Hide
|
C30H28ClFN4O6S
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0498216
|
6-{4-[(Biphenyl-2-carbonyl)-amino]-3-chloro-benzoyl}-3,4,5,6-tetrahydro-1H-azepino[4,3,2-cd]indole-2-sulfonic acid
Show/Hide
|
C31H24ClN3O5S
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0431134
|
6-{4-[(Biphenyl-2-carbonyl)-amino]-benzoyl}-3,4,5,6-tetrahydro-1H-azepino[4,3,2-cd]indole-2-sulfonic acid
Show/Hide
|
C31H25N3O5S
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0433271
|
1-({4-[(2-phenylbenzene)amido]phenyl}carbonyl)-1,2,3,5-tetrahydrospiro[1-benzazepine-4,1'-cyclopentan]-2'-ene-3'-carboxylic acid
Show/Hide
|
C35H30N2O4
|
2
|
| 1 |
IC50 = 14 nM
|
|
|
| 2 |
IC50 = 360 nM
|
|
|
|
CP0535728
|
Biphenyl-2-carboxylic acid [2-chloro-4-(1,3,4,5-tetrahydro-azepino[4,3,2-cd]indole-6-carbonyl)-phenyl]-amide
Show/Hide
|
C31H24ClN3O2
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0454096
|
N-[4-[1'-(hydroxymethyl)spiro[3,5-dihydro-2H-1-benzazepine-4,3'-cyclopentene]-1-carbonyl]phenyl]-2-phenylbenzamide
Show/Hide
|
C35H32N2O3
|
2
|
| 1 |
IC50 = 18 nM
|
|
|
| 2 |
IC50 = 190 nM
|
|
|
|
CP0230662
|
Biphenyl-2-carboxylic acid [4-(1,3,4,5-tetrahydro-azepino[4,3,2-cd]indole-6-carbonyl)-phenyl]-amide
Show/Hide
|
C31H25N3O2
|
2
|
| 1 |
IC50 = 20 nM
|
|
|
| 2 |
IC50 = 70 nM
|
|
|
|
CP0154509
|
3'N-(3-dimethylaminopropyl)-1-[4-(2-phenylphenylcarboxamido)benzoyl]spiro[2,3,4,5-tetrahydro-1H-benzo[b]azepine-4,1'-(2'-cyclopentene)]-3'-carboxamide
Show/Hide
|
C40H42N4O3
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0280289
|
3'N-(3-dimethylaminopropyl)-1-[4-(5-fluoro-2-methylphenylcarboxamido)benzoyl]spiro[2,3,4,5-tetrahydro-1H-benzo[b]azepine-4,1'-(2'-cyclopentene)]-3'-carboxamide
Show/Hide
|
C35H39FN4O3
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0454321
|
(4R)-1-({4-[(2-chloro-5-fluorobenzene)amido]-3-methoxyphenyl}carbonyl)-1,2,3,5-tetrahydrospiro[1-benzazepine-4,1'-cyclopentan]-2'-ene-3'-carboxylic acid
Show/Hide
|
C30H26ClFN2O5
|
2
|
| 1 |
IC50 = 34 nM
|
|
|
| 2 |
IC50 = 52 nM
|
|
|
|
CP0154510
|
(4S)-N-[2-(dimethylamino)ethyl]-1-[4-[(2-phenylbenzoyl)amino]benzoyl]spiro[3,5-dihydro-2H-1-benzazepine-4,3'-cyclopentene]-1'-carboxamide
Show/Hide
|
C39H40N4O3
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0454322
|
2-chloro-5-fluoro-N-(2-methoxy-4-{[(4R)-3'-(1H-1,2,3,4-tetrazol-5-yl)-1,2,3,5-tetrahydrospiro[1-benzazepine-4,1'-cyclopentan]-2'-en-1-yl]carbonyl}phenyl)benzamide
Show/Hide
|
C30H26ClFN6O3
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0467342
|
Biphenyl-2-carboxylic acid [4-(2-chloro-1,3,4,5-tetrahydro-azepino[4,3,2-cd]indole-6-carbonyl)-phenyl]-amide
Show/Hide
|
C31H24ClN3O2
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0489317
|
N-[4-[1'-(methylaminomethyl)spiro[3,5-dihydro-2H-1-benzazepine-4,3'-cyclopentene]-1-carbonyl]phenyl]-2-phenylbenzamide
Show/Hide
|
C36H35N3O2
|
2
|
| 1 |
IC50 = 44 nM
|
|
|
| 2 |
IC50 = 1800 nM
|
|
|
|
CP0304035
|
3'N-(2-tetrahydro-1H-1-pyrrolylethyl)-1-[4-(5-fluoro-2-methylphenylcarboxamido)benzoyl]spiro[2,3,4,5-tetrahydro-1H-benzo[b]azepine-4,1'-(2'-cyclopentene)]-3'-carboxamide
Show/Hide
|
C36H39FN4O3
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0502059
|
Biphenyl-2-carboxylic acid [3-chloro-4-(1,3,4,5-tetrahydro-azepino[4,3,2-cd]indole-6-carbonyl)-phenyl]-amide
Show/Hide
|
C31H24ClN3O2
|
2
|
| 1 |
IC50 = 50 nM
|
|
|
| 2 |
IC50 = 330 nM
|
|
|
|
CP0464259
|
(4R)-1-({4-[(2-chloro-5-fluorobenzene)amido]phenyl}carbonyl)-1,2,3,5-tetrahydrospiro[1-benzazepine-4,1'-cyclopentan]-2'-ene-3'-carboxylic acid
Show/Hide
|
C29H24ClFN2O4
|
2
|
| 1 |
IC50 = 53 nM
|
|
|
| 2 |
IC50 = 100 nM
|
|
|
|
CP0444371
|
(4R)-1-({4-[(2-chloro-5-fluorobenzene)amido]-3-ethoxyphenyl}carbonyl)-1,2,3,5-tetrahydrospiro[1-benzazepine-4,1'-cyclopentan]-2'-ene-3'-carboxylic acid
Show/Hide
|
C31H28ClFN2O5
|
2
|
| 1 |
IC50 = 71 nM
|
|
|
| 2 |
IC50 = 150 nM
|
|
|
|
CP0461696
|
1-({4-[(2-chloro-5-fluorobenzene)amido]phenyl}carbonyl)-1,2,3,5-tetrahydrospiro[1-benzazepine-4,1'-cyclopentan]-2'-ene-3'-carboxylic acid
Show/Hide
|
C29H24ClFN2O4
|
2
|
| 1 |
IC50 = 76 nM
|
|
|
| 2 |
IC50 = 410 nM
|
|
|
|
CP0461665
|
1-({4-[(2-chloro-5-fluorobenzene)amido]-3-methoxyphenyl}carbonyl)-1,2,3,5-tetrahydrospiro[1-benzazepine-4,1'-cyclopentan]-2'-ene-3'-carboxylic acid
Show/Hide
|
C30H26ClFN2O5
|
2
|
| 1 |
IC50 = 92 nM
|
|
|
| 2 |
IC50 = 120 nM
|
|
|
|
CP0124484
|
3'N-(2-dimethylaminoethyl)-1-[4-(2-phenylphenylcarboxamido)benzoyl]spiro[2,3,4,5-tetrahydro-1H-benzo[b]azepine-4,1'-(2'-cyclopentene)]-3'-carboxamide
Show/Hide
|
C39H40N4O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0056752
|
3'N-(2-dimethylaminoethyl)-1-[4-(5-fluoro-2-methylphenylcarboxamido)benzoyl]spiro[2,3,4,5-tetrahydro-1H-benzo[b]azepine-4,1'-(2'-cyclopentene)]-3'-carboxamide
Show/Hide
|
C34H37FN4O3
|
1
|
| 1 |
IC50 = 105 nM
|
|
|
|
CP0433270
|
1-({4-[(5-fluoro-2-methylbenzene)amido]-2-methoxyphenyl}carbonyl)-1,2,3,5-tetrahydrospiro[1-benzazepine-4,1'-cyclopentan]-2'-ene-3'-carboxylic acid
Show/Hide
|
C31H29FN2O5
|
2
|
| 1 |
IC50 = 110 nM
|
|
|
| 2 |
IC50 = 140 nM
|
|
|
|
CP0439720
|
4'-Methyl-biphenyl-2-carboxylic acid [4-(1-acetyl-1,3,4,5-tetrahydro-azepino[4,3,2-cd]indole-6-carbonyl)-phenyl]-amide
Show/Hide
|
C34H29N3O3
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0281438
|
3'N-(2-hydroxyethyl)-1-[4-(2-phenylphenylcarboxamido)benzoyl]spiro[2,3,4,5-tetrahydro-1H-benzo[b]azepine-4,1'-(2'-cyclopentene)]-3'-carboxamide
Show/Hide
|
C37H35N3O4
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0505714
|
3-Fluoro-2-methyl-N-[4-(1,3,4,5-tetrahydro-azepino[4,3,2-cd]indole-6-carbonyl)-phenyl]-benzamide
Show/Hide
|
C26H22FN3O2
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0523388
|
5-Fluoro-2-methyl-N-[4-(1,3,4,5-tetrahydro-azepino[4,3,2-cd]indole-6-carbonyl)-phenyl]-benzamide
Show/Hide
|
C26H22FN3O2
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0496421
|
4'-Methyl-biphenyl-2-carboxylic acid [4-(1-methyl-1,3,4,5-tetrahydro-azepino[4,3,2-cd]indole-6-carbonyl)-phenyl]-amide
Show/Hide
|
C33H29N3O2
|
1
|
| 1 |
IC50 = 210 nM
|
|
|
|
CP0154159
|
2-[1-[4-(2-phenylphenylcarboxamido)benzoyl]spiro[2,3,4,5-tetrahydro-1H-benzo[b]azepine-4,1'-(2'-cyclopentene)]-3-ylcarboxamido]acetic acid
Show/Hide
|
C37H33N3O5
|
1
|
| 1 |
IC50 = 350 nM
|
|
|
|
CP0289902
|
methyl 2-[[1-[4-[(5-fluoro-2-methylbenzoyl)amino]benzoyl]spiro[3,5-dihydro-2H-1-benzazepine-4,3'-cyclopentene]-1'-carbonyl]amino]acetate
Show/Hide
|
C33H32FN3O5
|
1
|
| 1 |
IC50 = 440 nM
|
|
|
|
CP0524572
|
(6-{4-[(4'-Methyl-biphenyl-2-carbonyl)-amino]-benzoyl}-3,4,5,6-tetrahydro-azepino[4,3,2-cd]indol-1-yl)-acetic acid ethyl ester
Show/Hide
|
C36H33N3O4
|
1
|
| 1 |
IC50 = 550 nM
|
|
|
|
CP0041307
|
(4R)-N-[2-(dimethylamino)ethyl]-1-[4-[(2-fluorobenzoyl)amino]benzoyl]spiro[3,5-dihydro-2H-1-benzazepine-4,3'-cyclopentene]-1'-carboxamide
Show/Hide
|
C33H35FN4O3
|
1
|
| 1 |
IC50 = 646 nM
|
|
|
|
CP0438918
|
2-chloro-5-fluoro-N-(4-{[(4R)-3'-(1H-imidazol-2-yl)-1,2,3,5-tetrahydrospiro[1-benzazepine-4,1'-cyclopentan]-2'-en-1-yl]carbonyl}-2-methoxyphenyl)benzamide
Show/Hide
|
C32H28ClFN4O3
|
1
|
| 1 |
IC50 = 730 nM
|
|
|
|
CP0433272
|
2-chloro-N-(4-{[(4R)-3'-(4,5-dihydro-1H-imidazol-2-yl)-1,2,3,5-tetrahydrospiro[1-benzazepine-4,1'-cyclopentan]-2'-en-1-yl]carbonyl}-2-methoxyphenyl)-5-fluorobenzamide
Show/Hide
|
C32H30ClFN4O3
|
1
|
| 1 |
IC50 = 1050 nM
|
|
|
|
CP0467938
|
(1S,5R)-1-(2-chloro-4-fluorophenyl)-3-[5-(ethoxymethyl)-4-(6-methoxypyridin-3-yl)-1,2,4-triazol-3-yl]-3-azabicyclo[3.1.0]hexane
Show/Hide
|
C22H23ClFN5O2
|
1
|
| 1 |
IC50 = 7320 nM
|
|
|
|
CP0461695
|
methyl 1-[4-[(2-chloro-5-fluorobenzoyl)amino]benzoyl]spiro[3,5-dihydro-2H-1-benzazepine-4,3'-cyclopentene]-1'-carboxylate
Show/Hide
|
C30H26ClFN2O4
|
2
|
| 1 |
IC50 > 10000 nM
|
|
|
| 2 |
IC50 > 200 nM
|
|
|
|
CP0464750
|
methyl 1-[4-[(2-fluorobenzoyl)amino]benzoyl]spiro[3,5-dihydro-2H-1-benzazepine-4,3'-cyclopentene]-1'-carboxylate
Show/Hide
|
C30H27FN2O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0440684
|
(1S,5R)-1-(2-chloro-4-fluorophenyl)-3-[5-(2-fluoroethoxymethyl)-4-(6-methoxypyridin-3-yl)-1,2,4-triazol-3-yl]-3-azabicyclo[3.1.0]hexane
Show/Hide
|
C22H22ClF2N5O2
|
1
|
| 1 |
IC50 = 21450 nM
|
|
|
|
CP0534259
|
(1S,5R)-1-(2-chloro-4-fluorophenyl)-3-[4-(6-methoxypyridin-3-yl)-5-[[(3S)-oxolan-3-yl]oxymethyl]-1,2,4-triazol-3-yl]-3-azabicyclo[3.1.0]hexane
Show/Hide
|
C24H25ClFN5O3
|
1
|
| 1 |
IC50 = 23047 nM
|
|
|
|
CP0479500
|
(1S,5R)-1-(2-chloro-3-fluorophenyl)-3-[5-(methoxymethyl)-4-(6-methoxypyridin-3-yl)-1,2,4-triazol-3-yl]-3-azabicyclo[3.1.0]hexane
Show/Hide
|
C21H21ClFN5O2
|
1
|
| 1 |
IC50 = 25665 nM
|
|
|
|
CP0169179
|
(1S,5R)-1-(2-chloro-4-fluorophenyl)-3-[5-(methoxymethyl)-4-(6-methoxypyridin-3-yl)-1,2,4-triazol-3-yl]-3-azabicyclo[3.1.0]hexane
Show/Hide
|
C21H21ClFN5O2
|
1
|
| 1 |
IC50 = 32604 nM
|
|
|
|
CP0105811
|
3'N-(2-tetrahydro-1H-1-pyrrolylethyl)-1-[4-(2-fluorophenylcarboxamido)benzoyl]spiro[2,3,4,5-tetrahydro-1H-benzo[b]azepine-4,1'-(2'-cyclopentene)]-3'-carboxamide
Show/Hide
|
C35H37FN4O3
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0194057
|
3'N-(2-dimethylaminoethyl)-1-[4-(2-fluorophenylcarboxamido)benzoyl]spiro[2,3,4,5-tetrahydro-1H-benzo[b]azepine-4,1'-(2'-cyclopentene)]-3'-carboxamide
Show/Hide
|
C33H35FN4O3
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0197121
|
3'N-(2-hydroxyethyl)-1-[4-(2-fluorophenylcarboxamido)benzoyl]spiro[2,3,4,5-tetrahydro-1H-benzo[b]azepine-4,1'-(2'-cyclopentene)]-3'-carboxamide
Show/Hide
|
C31H30FN3O4
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0304375
|
3'N-(2-hexahydro-1-pyridinylethyl)-1-[4-(2-fluorophenylcarboxamido)benzoyl]spiro[2,3,4,5-tetrahydro-1H-benzo[b]azepine-4,1'-(2'-cyclopentene)]-3'-carboxamide
Show/Hide
|
C36H39FN4O3
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0381621
|
1-ethyl-2-[(1E,3E,5Z)-5-[1-ethyl-3-methyl-3-[4-oxo-4-[2-[4-[[[4-oxo-4-[[1-[4-[(2-phenylbenzoyl)amino]benzoyl]-2,3,4,5-tetrahydro-1-benzazepin-5-yl]amino]butanoyl]amino]methyl]triazol-1-yl]ethylamino]butyl]-5-sulfoindol-2-ylidene]penta-1,3-dienyl]-3,3-dimethylindol-1-ium-5-sulfonate
Show/Hide
|
C71H76N10O11S2
|
1
|
| 1 |
Kd = 1.38 nM
|
|
|
|
CP0392288
|
1-ethyl-2-[(1E,3E,5E)-5-[1-ethyl-3-methyl-3-[4-oxo-4-[2-[2-[2-[2-[4-[[[4-oxo-4-[[1-[4-[(2-phenylbenzoyl)amino]benzoyl]-2,3,4,5-tetrahydro-1-benzazepin-5-yl]amino]butanoyl]amino]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethylamino]butyl]-5-sulfoindol-2-ylidene]penta-1,3-dienyl]-3,3-dimethylindol-1-ium-5-sulfonate
Show/Hide
|
C77H88N10O14S2
|
2
|
| 1 |
Kd = 2.33 nM
|
|
|
| 2 |
Ki = 1.93 nM
|
|
|
|
CP0436246
|
1-ethyl-2-[(1E,3E,5E)-5-[1-ethyl-3-methyl-3-[4-oxo-4-[2-[2-[2-[2-[2-[2-[2-[4-[[[4-oxo-4-[[1-[4-[(2-phenylbenzoyl)amino]benzoyl]-2,3,4,5-tetrahydro-1-benzazepin-5-yl]amino]butanoyl]amino]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethylamino]butyl]-5-sulfoindol-2-ylidene]penta-1,3-dienyl]-3,3-dimethylindol-1-ium-5-sulfonate
Show/Hide
|
C83H100N10O17S2
|
2
|
| 1 |
Kd = 2.53 nM
|
|
|
| 2 |
Ki = 0.83 nM
|
|
|
|
CP0376809
|
2-(3-hydroxy-6-oxoxanthen-9-yl)-5-[2-[2-[2-[2-[4-[[[4-oxo-4-[[1-[4-[(2-phenylbenzoyl)amino]benzoyl]-2,3,4,5-tetrahydro-1-benzazepin-5-yl]amino]butanoyl]amino]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethylcarbamothioylamino]benzoic acid
Show/Hide
|
C66H63N9O12S
|
1
|
| 1 |
Kd = 11.1 nM
|
|
|
|
CP0400285
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2-[(1E,3E,5Z)-5-[3-[4-[2-[3-[4-[(4-chlorophenyl)-[2-[(2-hydroxy-1H-indol-3-yl)diazenyl]-2-oxoethyl]sulfamoyl]phenyl]propanoylamino]ethylamino]-4-oxobutyl]-1-ethyl-3-methyl-5-sulfoindol-2-ylidene]penta-1,3-dienyl]-1-ethyl-3,3-dimethylindol-1-ium-6-sulfonate
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C59H63ClN8O12S3
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1
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| 1 |
Kd = 30.5 nM
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CP0400286
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CHEMBL3416749
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C54H48ClN7O12S
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1
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| 1 |
Kd = 135 nM
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CP0847937
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2-(5-(3-(1-(5-(3-(2-chloro-4-fluorophenoxy)azetidin-1-yl)-4-(6-methoxypyridinium-3-yl)-4H-1,2,4-triazol-3-yl)-27-oxo-2,5,8,11,14,17,20,23-octaoxa-26-azatriacontan-30-yl)-1-ethyl-3-methyl-5-sulfoindolin-2-ylidene)penta-1,3-dienyl)-1-ethyl-3,3-dimethyl-3H-indolium-6-sulfonate 2,2,2-trifluoroacetate
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C68H87ClF4N8O19S2
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1
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| 1 |
Kd = 353 nM
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CP0847936
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2-(5-(3-(1-(5-(3-(2-chloro-4-fluorophenoxy)azetidin-1-yl)-4-(6-methoxypyridinium-3-yl)-4H-1,2,4-triazol-3-yl)-15-oxo-2,5,8,11-tetraoxa-14-azaoctadecan-18-yl)-1-ethyl-3-methyl-5-sulfoindolin-2-ylidene)penta-1,3-dienyl)-1-ethyl-3,3-dimethyl-3H-indolium-6-sulfonate 2,2,2-trifluoroacetate
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C60H71ClF4N8O15S2
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1
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| 1 |
Kd = 509 nM
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CP0859026
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5-(3-(34-(3-carboxy-4-(3-oxo-3H-xanthen-9-yl)phenyl)-27,34-dioxo-2,5,8,11,14,17,20,23-octaoxa-26,33-diazatetratriacontyl)-5-(3-(2-chloro-4-fluorophenoxy)azetidin-1-yl)-4H-1,2,4-triazol-4-yl)-2-methoxypyridinium 2,2,2-trifluoroacetate
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C63H72ClF4N7O19
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1
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| 1 |
Kd > 1000 nM
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CP0859027
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5-(3-(22-(3-carboxy-4-(3-oxo-3H-xanthen-9-yl)phenyl)-15,22-dioxo-2,5,8,11-tetraoxa-14,21-diazadocosyl)-5-(3-(2-chloro-4-fluorophenoxy)azetidin-1-yl)-4H-1,2,4-triazol-4-yl)-2-methoxypyridinium 2,2,2-trifluoroacetate
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C55H56ClF4N7O15
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1
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| 1 |
Kd > 1000 nM
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CP0392030
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N-[4-(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl)-3-methylphenyl]-2-methylbenzamide
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C26H25ClN2O3
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2
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| 1 |
Ki = 1.7 nM
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| 2 |
Ki = 2.4 nM
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CP0569758
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N-[4-[7-chloro-5-[(3-morpholin-4-yl-3-oxopropyl)amino]-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl]-3-methylphenyl]-2-methylbenzamide
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C33H37ClN4O4
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1
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| 1 |
Ki = 3.8 nM
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CP0579758
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N-[4-[1-(3-morpholin-4-ylpropyl)-3,4-dihydro-2H-1,5-benzodiazepine-5-carbonyl]phenyl]-2-phenylbenzamide
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C36H38N4O3
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1
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| 1 |
Ki = 4.3 nM
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CP0568221
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N-[4-[7-chloro-5-(2-morpholin-4-ylethylamino)-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl]-3-methylphenyl]-2-methylbenzamide
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C32H37ClN4O3
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1
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| 1 |
Ki = 6.9 nM
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CP0106503
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3-chloro-4-[16-methyl-(12S)-2,10-diazatetracyclo[11.2.1.02,12.04,9]hexadeca-4(9),5,7-trien-10-ylcarbonyl]-1-(2-phenylphenylcarboxamido)benzene
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C34H30ClN3O2
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1
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| 1 |
Ki = 9 nM
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CP0206403
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1N-{4-[6-chloro-16-methyl-(12S)-2,10-diazatetracyclo[11.2.1.02,12.04,9]hexadeca-4(9),5,7-trien-10-ylcarbonyl]phenyl}-2-trifluoromethylbenzamide
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C29H25ClF3N3O2
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1
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| 1 |
Ki = 9 nM
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CP0544949
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N-[4-[1-[3-(4-ethylpiperazin-1-yl)propyl]-3,4-dihydro-2H-1,5-benzodiazepine-5-carbonyl]phenyl]-2-phenylbenzamide
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C38H43N5O2
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1
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| 1 |
Ki = 9 nM
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CP0570126
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N-[4-[1-[3-(diethylamino)propyl]-3,4-dihydro-2H-1,5-benzodiazepine-5-carbonyl]phenyl]-2-phenylbenzamide
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C36H40N4O2
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1
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| 1 |
Ki = 10 nM
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CP0577395
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N-[4-[7-chloro-5-(3-pyridin-4-ylpropylamino)-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl]-3-methylphenyl]-2-methylbenzamide
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C34H35ClN4O2
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1
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| 1 |
Ki = 10 nM
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CP0568303
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N-[4-[7-chloro-5-(3-morpholin-4-ylpropylamino)-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl]-3-methylphenyl]-2-methylbenzamide
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C33H39ClN4O3
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1
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| 1 |
Ki = 11 nM
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CP0575614
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2-phenyl-N-[4-[1-(3-piperidin-1-ylpropyl)-3,4-dihydro-2H-1,5-benzodiazepine-5-carbonyl]phenyl]benzamide
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C37H40N4O2
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1
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| 1 |
Ki = 12 nM
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CP0577519
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N-[3-methyl-4-[1-(3-morpholin-4-ylpropyl)-3,4-dihydro-2H-1,5-benzodiazepine-5-carbonyl]phenyl]-2-phenylbenzamide
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C37H40N4O3
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1
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| 1 |
Ki = 12 nM
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CP0570408
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N-[4-[7-chloro-5-[3-(4-methylpiperazin-1-yl)propylamino]-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl]-3-methylphenyl]-2-methylbenzamide
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C34H42ClN5O2
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1
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| 1 |
Ki = 12 nM
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CP0196743
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1N-{4-[6-chloro-16-methyl-(12S)-2,10-diazatetracyclo[11.2.1.02,12.04,9]hexadeca-4(9),5,7-trien-10-ylcarbonyl]phenyl}-2-(4-methylphenyl)benzamide
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C35H32ClN3O2
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1
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| 1 |
Ki = 13 nM
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CP0577645
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N-[4-[1-[3-(4-methylpiperazin-1-yl)propyl]-3,4-dihydro-2H-1,5-benzodiazepine-5-carbonyl]phenyl]-2-phenylbenzamide
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C37H41N5O2
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1
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| 1 |
Ki = 13 nM
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CP0569392
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N-[4-[7-chloro-5-(3-piperidin-1-ylpropylamino)-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl]-3-methylphenyl]-2-methylbenzamide
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C34H41ClN4O2
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1
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| 1 |
Ki = 13 nM
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CP0567789
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2-(4-methylphenyl)-N-[4-[1-(3-morpholin-4-ylpropyl)-3,4-dihydro-2H-1,5-benzodiazepine-5-carbonyl]phenyl]benzamide
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C37H40N4O3
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1
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| 1 |
Ki = 18 nM
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CP0577524
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N-[4-[1-(4-morpholin-4-ylbutyl)-3,4-dihydro-2H-1,5-benzodiazepine-5-carbonyl]phenyl]-2-phenylbenzamide
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C37H40N4O3
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1
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| 1 |
Ki = 23 nM
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CP0575615
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N-[4-[1-(2-morpholin-4-ylethyl)-3,4-dihydro-2H-1,5-benzodiazepine-5-carbonyl]phenyl]-2-phenylbenzamide
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C35H36N4O3
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1
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| 1 |
Ki = 26 nM
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CP0227811
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3-chloro-4-[16-methyl-(12R)-2,10-diazatetracyclo[11.2.1.02,12.04,9]hexadeca-4(9),5,7-trien-10-ylcarbonyl]-1-(2-phenylphenylcarboxamido)benzene
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C34H30ClN3O2
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1
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| 1 |
Ki = 30 nM
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CP0545024
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N-[4-[7-chloro-5-(4-morpholin-4-ylbutylamino)-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl]-3-methylphenyl]-2-methylbenzamide
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C34H41ClN4O3
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1
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| 1 |
Ki = 31 nM
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CP0550330
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N-[4-[7-chloro-5-[3-(diethylamino)propylamino]-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl]-3-methylphenyl]-2-methylbenzamide
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C33H41ClN4O2
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1
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| 1 |
Ki = 31 nM
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CP0219489
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1N-{4-[6-chloro-16-methyl-(12S)-2,10-diazatetracyclo[11.2.1.02,12.04,9]hexadeca-4(9),5,7-trien-10-ylcarbonyl]phenyl}-2-chlorobenzamide
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C28H25Cl2N3O2
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1
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| 1 |
Ki = 32 nM
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CP0577520
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N-[4-[7-chloro-1-(3-morpholin-4-ylpropyl)-3,4-dihydro-2H-1,5-benzodiazepine-5-carbonyl]phenyl]-2-phenylbenzamide
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C36H37ClN4O3
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1
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| 1 |
Ki = 35 nM
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CP0569765
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N-[4-[7-chloro-5-(5-morpholin-4-ylpentylamino)-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl]-3-methylphenyl]-2-methylbenzamide
Show/Hide
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C35H43ClN4O3
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1
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| 1 |
Ki = 39 nM
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CP0578417
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N-[4-[1-[3-(dimethylamino)propyl]-3,4-dihydro-2H-1,5-benzodiazepine-5-carbonyl]phenyl]-2-phenylbenzamide
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C34H36N4O2
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1
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| 1 |
Ki = 51 nM
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CP0577517
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2-methyl-N-[4-[1-(3-morpholin-4-ylpropyl)-3,4-dihydro-2H-1,5-benzodiazepine-5-carbonyl]phenyl]benzamide
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C31H36N4O3
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1
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| 1 |
Ki = 61 nM
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CP0577674
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5-fluoro-2-methyl-N-[4-[1-(3-morpholin-4-ylpropyl)-3,4-dihydro-2H-1,5-benzodiazepine-5-carbonyl]phenyl]benzamide
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C31H35FN4O3
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1
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| 1 |
Ki = 64 nM
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CP0550112
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2-phenyl-N-[4-[1-(3-pyrrolidin-1-ylpropyl)-3,4-dihydro-2H-1,5-benzodiazepine-5-carbonyl]phenyl]benzamide
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C36H38N4O2
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1
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| 1 |
Ki = 67 nM
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CP0544946
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2,4-dichloro-N-[4-[1-(3-morpholin-4-ylpropyl)-3,4-dihydro-2H-1,5-benzodiazepine-5-carbonyl]phenyl]benzamide
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C30H32Cl2N4O3
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1
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| 1 |
Ki = 99 nM
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CP0579867
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2-bromo-N-[4-[1-(3-morpholin-4-ylpropyl)-3,4-dihydro-2H-1,5-benzodiazepine-5-carbonyl]phenyl]benzamide
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C30H33BrN4O3
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1
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| 1 |
Ki = 107 nM
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CP0365138
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2-Methyl-N-[4-(2,3,4,5-tetrahydro-benzo[b][1,4]diazepine-1-carbonyl)-phenyl]-benzamide
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C24H23N3O2
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1
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| 1 |
Ki = 160 nM
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CP0104567
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1N-{4-[6-chloro-16-methyl-(12S)-2,10-diazatetracyclo[11.2.1.02,12.04,9]hexadeca-4(9),5,7-trien-10-ylcarbonyl]phenyl}-2-fluorobenzamide
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C28H25ClFN3O2
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1
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| 1 |
Ki = 180 nM
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CP0062116
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1N-{4-[6-chloro-16-ethyl-(12S)-2,10-diazatetracyclo[11.2.1.02,12.04,9]hexadeca-4(9),5,7-trien-10-ylcarbonyl]phenyl}-2-chlorobenzamide
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C29H27Cl2N3O2
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1
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| 1 |
Ki = 520 nM
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CP0544948
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4-fluoro-N-[4-[1-(3-morpholin-4-ylpropyl)-3,4-dihydro-2H-1,5-benzodiazepine-5-carbonyl]phenyl]benzamide
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C30H33FN4O3
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1
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| 1 |
Ki = 543 nM
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CP0545137
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3,4-dichloro-N-[4-[1-(3-morpholin-4-ylpropyl)-3,4-dihydro-2H-1,5-benzodiazepine-5-carbonyl]phenyl]benzamide
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C30H32Cl2N4O3
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1
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| 1 |
Ki = 638 nM
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CP0571220
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2-fluoro-N-[4-[1-(3-morpholin-4-ylpropyl)-3,4-dihydro-2H-1,5-benzodiazepine-5-carbonyl]phenyl]benzamide
Show/Hide
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C30H33FN4O3
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1
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| 1 |
Ki = 646 nM
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CP0569307
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N-[4-[1-(3-morpholin-4-ylpropyl)-3,4-dihydro-2H-1,5-benzodiazepine-5-carbonyl]phenyl]benzamide
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C30H34N4O3
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1
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| 1 |
Ki = 654 nM
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CP0579383
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N-[4-[1-(3-morpholin-4-ylpropyl)-3,4-dihydro-2H-1,5-benzodiazepine-5-carbonyl]phenyl]-4-phenylbenzamide
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C36H38N4O3
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1
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| 1 |
Ki = 1357 nM
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CP0405331
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(2S)-2-(dimethylcarbamothioyl)-N-[[2-methyl-4-(1-methyl-4,10-dihydropyrazolo[4,3-c][1,5]benzodiazepine-5-carbonyl)phenyl]methyl]pyrrolidine-1-carboxamide
Show/Hide
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C28H33N7O2S
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1
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| 1 |
Ki = 1666 nM
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CP0246508
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(1-benzyl-2-methylindol-3-yl)-spiro[1H-2-benzofuran-3,4'-piperidine]-1'-ylmethanone
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C29H28N2O2
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1
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| 1 |
Ki = 9308 nM
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CP0441646
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(6-chloro-1H-indol-3-yl)-spiro[1H-2-benzofuran-3,4'-piperidine]-1'-ylmethanone
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C21H19ClN2O2
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1
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| 1 |
Ki > 27000 nM
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CP0078819
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(2S)-N-{2-Methyl-4-[(1-methyl-4,10-dihydropyrazolo[3,4-b]-[1,5]benzodiazepin-5(1H)-yl)carbonyl]benzyl}-2-[(4-methyl-1,4-diazepan-1-yl)carbonothioyl]pyrrolidine-1-carboxamide
Show/Hide
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C32H40N8O2S
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1
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| 1 |
Ki > 1000 nM
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CP0219136
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4-[(3,5-dihydroxyphenyl)methyl]-N-[[2-methyl-4-(1-methyl-4,10-dihydropyrazolo[4,3-c][1,5]benzodiazepine-5-carbonyl)phenyl]methyl]piperazine-1-carboxamide
Show/Hide
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C32H35N7O4
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1
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| 1 |
Ki > 1000 nM
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CP0387123
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methyl 2-[[2-methyl-4-(1-methyl-4,10-dihydropyrazolo[4,3-c][1,5]benzodiazepine-5-carbonyl)phenyl]methylcarbamoylamino]acetate
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C24H26N6O4
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1
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| 1 |
Ki > 1000 nM
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CP0387124
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(2S)-2-N,2-N-dimethyl-1-N-[[2-methyl-4-(1-methyl-4,10-dihydropyrazolo[4,3-c][1,5]benzodiazepine-5-carbonyl)phenyl]methyl]pyrrolidine-1,2-dicarboxamide
Show/Hide
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C28H33N7O3
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1
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| 1 |
Ki > 1000 nM
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CP0410989
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1-[2-(dimethylamino)-2-sulfanylideneethyl]-3-[[2-methyl-4-(1-methyl-4,10-dihydropyrazolo[4,3-c][1,5]benzodiazepine-5-carbonyl)phenyl]methyl]urea
Show/Hide
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C25H29N7O2S
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1
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| 1 |
Ki > 1000 nM
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CP0410990
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N,N-dimethyl-2-[[2-methyl-4-(1-methyl-4,10-dihydropyrazolo[4,3-c][1,5]benzodiazepine-5-carbonyl)phenyl]methylcarbamoylamino]acetamide
Show/Hide
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C25H29N7O3
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1
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| 1 |
Ki > 1000 nM
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CP0386760
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(5R,8S,11S,14S,17S)-8-(2-amino-2-oxoethyl)-11-(3-amino-3-oxopropyl)-14-[(2S)-butan-2-yl]-17-[(4-hydroxyphenyl)methyl]-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.4.0]octacosa-1(28),24,26-triene-5-carbonyl]pyrrolidine-2-carboxamide
Show/Hide
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C51H73N11O12S2
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1
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| 1 |
Ki > 6000 nM
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CP0387328
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(5R,8S,11S,14S,17S)-8-(2-amino-2-oxoethyl)-11-(3-amino-3-oxopropyl)-14-[(2S)-butan-2-yl]-17-[(4-hydroxyphenyl)methyl]-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.3.1]octacosa-1(27),24(28),25-triene-5-carbonyl]pyrrolidine-2-carboxamide
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C51H73N11O12S2
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1
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| 1 |
Ki > 6000 nM
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CP0430562
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-1-[(5R,8S,11S,14S,17S)-8-(2-amino-2-oxoethyl)-11-(3-amino-3-oxopropyl)-14-[(2S)-butan-2-yl]-17-[(4-hydroxyphenyl)methyl]-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.4.0]octacosa-1(28),24,26-triene-5-carbonyl]pyrrolidine-2-carboxamide
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C51H74N14O12S2
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1
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| 1 |
Ki > 6000 nM
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CP0476263
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-2,21-dithia-5,8,11,14,17-pentazabicyclo[21.2.2]heptacosa-1(25),23,26-triene-4-carbonyl]pyrrolidine-2-carboxamide
Show/Hide
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C50H71N11O12S2
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1
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| 1 |
Ki > 6000 nM
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