Brief Information of the Compound and Protein
Compound Name
1-({4-[(2-chloro-5-fluorobenzene)amido]phenyl}carbonyl)-1,2,3,5-tetrahydrospiro[1-benzazepine-4,1'-cyclopentan]-2'-ene-3'-carboxylic acid
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PubChem ID
CID: 44444760
Canonical SMILES
OC(=O)C1=CC2(CC1)CCN(C(=O)c1ccc(NC(=O)c3cc(F)ccc3Cl)cc1)c1ccccc1C2
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Compound Formula C29H24ClFN2O4
Compound Structure
Protein Name
Vasopressin V2 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Vasopressin and oxytocin receptor
Uniprot ID
P30518
Gene Name
AVPR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 76 nM
   TI
   LI
   LO
   TS
2
IC50 = 410 nM
   TI
   LI
   LO
   TS