| Compound ID |
Compound Name |
Compound Formula |
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CP0261968
|
6-[[4-[(4-aminocyclohexyl)amino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]-2-methylisoquinolin-1-one
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C21H23F3N6O
|
1
|
| 1 |
IC50 = 3.56 nM
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|
|
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CP0261969
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CHEMBL5092606
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C20H25F3N6O
|
1
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| 1 |
IC50 = 6.25 nM
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|
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CP0381932
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N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-5-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridine-2-carboxamide
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C29H38N6O4
|
1
|
| 1 |
Kd = 0.3 nM
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|
|
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CP0441092
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N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-5-(1-cyclopropylpiperidin-4-yl)oxypyridine-2-carboxamide
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C28H34N6O4
|
1
|
| 1 |
Kd = 0.4 nM
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|
|
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CP0481760
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N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-5-(1-tert-butylpiperidin-4-yl)oxypyridine-2-carboxamide
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C29H38N6O4
|
1
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| 1 |
Kd = 0.4 nM
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|
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CP0523502
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N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-5-[(1-ethylpiperidin-4-yl)methyl]pyridine-2-carboxamide
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C28H36N6O3
|
1
|
| 1 |
Kd = 0.4 nM
|
|
|
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CP0002211
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N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
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|
C22H27FN4O2
|
1
|
| 1 |
Kd = 0.47 nM
|
|
|
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CP0086291
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N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-5-(1,2,2,6,6-pentamethylpiperidin-4-yl)oxypyridine-2-carboxamide
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|
C30H40N6O4
|
1
|
| 1 |
Kd = 0.5 nM
|
|
|
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CP0086292
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N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-5-(1-ethylpiperidin-4-yl)oxypyridine-2-carboxamide
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|
C27H34N6O4
|
1
|
| 1 |
Kd = 0.5 nM
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|
|
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CP0120915
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N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-5-(1-ethyl-2,2,6,6-tetramethylpiperidin-4-yl)oxypyridine-2-carboxamide
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|
C31H42N6O4
|
1
|
| 1 |
Kd = 0.5 nM
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|
|
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CP0499589
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N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-5-methylpyridine-2-carboxamide
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|
C21H23N5O3
|
1
|
| 1 |
Kd = 0.6 nM
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|
|
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CP0523443
|
N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-5-(1-propan-2-ylpiperidin-4-yl)oxypyridine-2-carboxamide
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|
C28H36N6O4
|
1
|
| 1 |
Kd = 0.6 nM
|
|
|
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CP0127888
|
AB-460
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|
C24H23N5O3
|
1
|
| 1 |
Kd = 0.7 nM
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|
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CP0518142
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N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-5-piperidin-4-yloxypyridine-2-carboxamide
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|
C25H30N6O4
|
1
|
| 1 |
Kd = 0.7 nM
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|
|
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CP0458958
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N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-4-methylpyridine-2-carboxamide
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C21H23N5O3
|
1
|
| 1 |
Kd = 0.8 nM
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|
|
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CP0381929
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N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-5-[(4-methylpiperazin-1-yl)methyl]pyridine-2-carboxamide
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|
C26H33N7O3
|
1
|
| 1 |
Kd = 0.9 nM
|
|
|
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CP0510461
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1-(5-tert-Butyl-isoxazol-3-yl)-3-{4-[7-(4-ethyl-piperazine-1-carbonyl)-benzo[d]imidazo[2,1-b]thiazol-2-yl]-phenyl}-urea
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|
C30H33N7O3S
|
1
|
| 1 |
Kd = 0.98 nM
|
|
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CP0398548
|
1-(5-tert-butyl-1,2-oxazol-3-yl)-3-[4-[6-(3-morpholin-4-ylpropoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl]urea
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|
C30H34N6O4S
|
1
|
| 1 |
Kd = 0.99 nM
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|
|
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CP0523444
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N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-4-(1-ethylpiperidin-4-yl)oxypyridine-2-carboxamide
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|
C27H34N6O4
|
1
|
| 1 |
Kd = 1 nM
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|
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CP0502995
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1-(5-tert-butyl-1,2-oxazol-3-yl)-3-[4-[6-[(4-ethylpiperazin-1-yl)methyl]imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl]urea
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|
C30H35N7O2S
|
1
|
| 1 |
Kd = 1.1 nM
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|
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CP0499978
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1-(5-tert-butyl-1,2-oxazol-3-yl)-3-[4-[6-(4-methylpiperazin-1-yl)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl]urea
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|
C28H31N7O2S
|
1
|
| 1 |
Kd = 1.2 nM
|
|
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CP0458957
|
N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-4-piperidin-4-yloxypyridine-2-carboxamide
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|
C25H30N6O4
|
1
|
| 1 |
Kd = 1.2 nM
|
|
|
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CP0473640
|
3-(2-{4-[3-(5-tert-Butyl-isoxazol-3-yl)ureido]phenyl}imidazo[2,1-b][1,3]benzothiazol-7-yl)propanoate
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|
C26H25N5O4S
|
1
|
| 1 |
Kd = 1.3 nM
|
|
|
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CP0473642
|
1-(5-tert-butyl-1,2-oxazol-3-yl)-3-[4-[6-(3-morpholin-4-ylpropyl)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl]urea
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|
C30H34N6O3S
|
1
|
| 1 |
Kd = 1.3 nM
|
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CP0455137
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1-(5-tert-butyl-1,2-oxazol-3-yl)-3-[4-[6-(3-morpholin-4-yl-3-oxopropyl)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl]urea
Show/Hide
|
C30H32N6O4S
|
1
|
| 1 |
Kd = 1.5 nM
|
|
|
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CP0469512
|
1-(5-tert-butyl-1,2-oxazol-3-yl)-3-[4-[6-(2-piperidin-1-ylethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl]urea
Show/Hide
|
C30H34N6O3S
|
1
|
| 1 |
Kd = 1.5 nM
|
|
|
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CP0523442
|
N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-5-(1-ethylpiperidin-4-yl)pyridine-2-carboxamide
Show/Hide
|
C27H34N6O3
|
1
|
| 1 |
Kd = 1.5 nM
|
|
|
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CP0030740
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1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morpholin-4-Yl)ethoxy]imidazo[2,1-B][1,3]benzothiazol-2-Yl}phenyl)urea
Show/Hide
|
C29H32N6O4S
|
1
|
| 1 |
Kd = 1.6 nM
|
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|
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CP0061797
|
Benzo[d]imidazo[2,1-b]thiazole-2-carboxylic acid {4-[3-(5-tert-butyl-isoxazol-3-yl)-ureido]-phenyl}-amide
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|
C24H22N6O3S
|
1
|
| 1 |
Kd = 1.6 nM
|
|
|
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CP0502955
|
2-{4-[3-(5-tert-Butyl-isoxazol-3-yl)ureido]phenyl}imidazo[2,1-b][1,3]benzothiazole-7-carboxylate
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|
C24H21N5O4S
|
1
|
| 1 |
Kd = 1.6 nM
|
|
|
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CP0497170
|
1-(5-tert-butyl-1,2-oxazol-3-yl)-3-[4-[6-[3-(4-methylpiperazin-1-yl)propoxy]imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl]urea
Show/Hide
|
C31H37N7O3S
|
1
|
| 1 |
Kd = 1.7 nM
|
|
|
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CP0452364
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1-(5-tert-butyl-1,2-oxazol-3-yl)-3-(4-imidazo[2,1-b][1,3]benzothiazol-2-ylphenyl)urea
Show/Hide
|
C23H21N5O2S
|
1
|
| 1 |
Kd = 1.9 nM
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CP0398549
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1-(5-tert-butyl-1,2-oxazol-3-yl)-3-[4-[6-[3-(4-ethylpiperazin-1-yl)-3-oxopropyl]imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl]urea
Show/Hide
|
C32H37N7O3S
|
1
|
| 1 |
Kd = 2 nM
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CP0388135
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1-(5-tert-butyl-1,2-oxazol-3-yl)-3-[4-[7-(2-morpholin-4-ylethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl]urea
Show/Hide
|
C29H32N6O4S
|
1
|
| 1 |
Kd = 2.3 nM
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CP0498453
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1-(5-tert-butyl-1,2-oxazol-3-yl)-3-[4-(6-hydroxyimidazo[2,1-b][1,3]benzothiazol-2-yl)phenyl]urea
Show/Hide
|
C23H21N5O3S
|
1
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| 1 |
Kd = 2.7 nM
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CP0441094
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N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-5-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]oxypyridine-2-carboxamide
Show/Hide
|
C27H31F3N6O4
|
1
|
| 1 |
Kd = 3.4 nM
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CP0473637
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1-(5-tert-butyl-1,2-oxazol-3-yl)-3-[4-[8-(2-morpholin-4-ylethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl]urea
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|
C29H32N6O4S
|
1
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| 1 |
Kd = 5.2 nM
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CP0460455
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1-(5-tert-butyl-1,2-oxazol-3-yl)-3-[4-[6-[3-(4-methylsulfonylpiperazin-1-yl)propoxy]imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl]urea
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C31H37N7O5S2
|
1
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| 1 |
Kd = 9.7 nM
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CP0018477
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4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide
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C21H16ClF3N4O3
|
1
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| 1 |
Kd = 13 nM
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