| Compound ID |
Compound Name |
Compound Formula |
|
CP0198243
|
(6S)-6-amino-20-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]-1,8,15,17,23-pentazatricyclo[14.5.2.019,22]tricosa-16,18,20,22-tetraen-7-one
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|
C30H44N8O
|
1
|
| 1 |
EC50 = 34 nM
|
|
|
|
CP0046964
|
16-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]-1,11,13,19-tetrazatricyclo[10.5.2.015,18]nonadeca-12,14,16,18-tetraen-5-ol
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|
C27H38N6O
|
1
|
| 1 |
EC50 = 39 nM
|
|
|
|
CP0176167
|
18-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]-1,13,15,21-tetrazatricyclo[12.5.2.017,20]henicosa-14,16,18,20-tetraen-5-ol
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|
C29H42N6O
|
1
|
| 1 |
EC50 = 43 nM
|
|
|
|
CP0060304
|
18-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]-1,13,15,21-tetrazatricyclo[12.5.2.017,20]henicosa-14,16,18,20-tetraen-7-ol
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|
C29H42N6O
|
1
|
| 1 |
EC50 = 69 nM
|
|
|
|
CP0046963
|
20-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]-1,15,17,23-tetrazatricyclo[14.5.2.019,22]tricosa-16,18,20,22-tetraen-6-ol
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|
C31H46N6O
|
1
|
| 1 |
EC50 = 72 nM
|
|
|
|
CP0085838
|
19-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]-1,14,16,22-tetrazatricyclo[13.5.2.018,21]docosa-15,17,19,21-tetraen-6-ol
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|
C30H44N6O
|
1
|
| 1 |
EC50 = 110 nM
|
|
|
|
CP0198240
|
19-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]-1,14,16,22-tetrazatricyclo[13.5.2.018,21]docosa-15,17,19,21-tetraen-7-ol
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|
C30H44N6O
|
1
|
| 1 |
EC50 = 120 nM
|
|
|
|
CP0326622
|
20-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]-1,15,17,23-tetrazatricyclo[14.5.2.019,22]tricosa-16,18,20,22-tetraen-7-ol
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|
C31H46N6O
|
1
|
| 1 |
EC50 = 150 nM
|
|
|
|
CP0558278
|
17-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]-1,12,14,20-tetrazatricyclo[11.5.2.016,19]icosa-13,15,17,19-tetraen-6-ol
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|
C28H40N6O
|
1
|
| 1 |
EC50 = 150 nM
|
|
|
|
CP0094327
|
19-[4-(morpholin-4-ylmethyl)phenyl]-1,14,16,22-tetrazatricyclo[13.5.2.018,21]docosa-15,17,19,21-tetraen-6-ol
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|
C29H41N5O2
|
1
|
| 1 |
EC50 = 160 nM
|
|
|
|
CP0140081
|
(6S)-6-amino-22-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]-1,8,17,19,25-pentazatricyclo[16.5.2.021,24]pentacosa-18,20,22,24-tetraen-7-one
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|
C32H48N8O
|
1
|
| 1 |
EC50 = 160 nM
|
|
|
|
CP0046837
|
19-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]-1,14,16,22-tetrazatricyclo[13.5.2.018,21]docosa-15,17,19,21-tetraen-5-ol
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|
C30H44N6O
|
1
|
| 1 |
EC50 = 190 nM
|
|
|
|
CP0198242
|
[4-(6-hydroxy-1,14,16,22-tetrazatricyclo[13.5.2.018,21]docosa-15,17,19,21-tetraen-19-yl)phenyl]-morpholin-4-ylmethanone
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|
C29H39N5O3
|
1
|
| 1 |
EC50 = 210 nM
|
|
|
|
CP0060303
|
19-(4-morpholin-4-ylsulfonylphenyl)-1,14,16,22-tetrazatricyclo[13.5.2.018,21]docosa-15,17,19,21-tetraen-6-ol
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|
C28H39N5O4S
|
1
|
| 1 |
EC50 = 220 nM
|
|
|
|
CP0140241
|
17-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]-1,12,14,20-tetrazatricyclo[11.5.2.016,19]icosa-13,15,17,19-tetraen-5-ol
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|
C28H40N6O
|
1
|
| 1 |
EC50 = 240 nM
|
|
|
|
CP0140008
|
19-pyridin-4-yl-1,14,16,22-tetrazatricyclo[13.5.2.018,21]docosa-15,17,19,21-tetraen-6-ol
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|
C23H31N5O
|
1
|
| 1 |
EC50 = 260 nM
|
|
|
|
CP0046996
|
19-pyridin-3-yl-1,14,16,22-tetrazatricyclo[13.5.2.018,21]docosa-15,17,19,21-tetraen-6-ol
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|
C23H31N5O
|
1
|
| 1 |
EC50 = 380 nM
|
|
|
|
CP0176174
|
21-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]-1,16,18,24-tetrazatricyclo[15.5.2.020,23]tetracosa-17,19,21,23-tetraen-7-ol
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|
C32H48N6O
|
1
|
| 1 |
EC50 = 400 nM
|
|
|
|
CP0140014
|
N-[4-(6-hydroxy-1,14,16,22-tetrazatricyclo[13.5.2.018,21]docosa-15,17,19,21-tetraen-19-yl)phenyl]morpholine-4-carboxamide
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|
C29H40N6O3
|
1
|
| 1 |
EC50 = 490 nM
|
|
|
|
CP0046834
|
19-(4-morpholin-4-ylphenyl)-1,14,16,22-tetrazatricyclo[13.5.2.018,21]docosa-15,17,19,21-tetraen-6-ol
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|
C28H39N5O2
|
1
|
| 1 |
EC50 = 690 nM
|
|
|
|
CP0046839
|
19-pyridin-2-yl-1,14,16,22-tetrazatricyclo[13.5.2.018,21]docosa-15,17,19,21-tetraen-6-ol
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|
C23H31N5O
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0046998
|
19-(4-fluorophenyl)-1,14,16,22-tetrazatricyclo[13.5.2.018,21]docosa-15,17,19,21-tetraen-6-ol
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|
C24H31FN4O
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0060311
|
19-(2-methoxyphenyl)-1,14,16,22-tetrazatricyclo[13.5.2.018,21]docosa-15,17,19,21-tetraen-6-ol
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|
C25H34N4O2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0094329
|
19-phenyl-1,14,16,22-tetrazatricyclo[13.5.2.018,21]docosa-15,17,19,21-tetraen-6-ol
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|
C24H32N4O
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0140010
|
(5S)-5-amino-19-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]-1,7,14,16,22-pentazatricyclo[13.5.2.018,21]docosa-15,17,19,21-tetraen-6-one
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|
C29H42N8O
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0140011
|
(5S)-5-amino-17-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]-1,7,12,14,20-pentazatricyclo[11.5.2.016,19]icosa-13,15,17,19-tetraen-6-one
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|
C27H38N8O
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0140013
|
19-(4-methoxyphenyl)-1,14,16,22-tetrazatricyclo[13.5.2.018,21]docosa-15,17,19,21-tetraen-6-ol
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|
C25H34N4O2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0176118
|
19-(3-methoxyphenyl)-1,14,16,22-tetrazatricyclo[13.5.2.018,21]docosa-15,17,19,21-tetraen-6-ol
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|
C25H34N4O2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0180227
|
19-(oxan-4-yl)-1,14,16,22-tetrazatricyclo[13.5.2.018,21]docosa-15,17,19,21-tetraen-6-ol
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|
C23H36N4O2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0180230
|
(6S)-6-amino-18-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]-1,8,13,15,21-pentazatricyclo[12.5.2.017,20]henicosa-14,16,18,20-tetraen-7-one
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|
C28H40N8O
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0198241
|
(5S)-5-amino-21-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]-1,7,16,18,24-pentazatricyclo[15.5.2.020,23]tetracosa-17,19,21,23-tetraen-6-one
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|
C31H46N8O
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
