Brief Information of the Compound and Protein
Compound Name
19-pyridin-4-yl-1,14,16,22-tetrazatricyclo[13.5.2.018,21]docosa-15,17,19,21-tetraen-6-ol
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PubChem ID
CID: 134153576
Canonical SMILES
OC1CCCCCCCNc2ncc3c(cn(CCCC1)c3n2)-c1ccncc1
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Compound Formula C23H31N5O
Compound Structure
Protein Name
Tyrosine-protein kinase Mer
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Axl family
Uniprot ID
Q12866
Gene Name
MERTK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 260 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 80 nM