| Compound ID |
Compound Name |
Compound Formula |
|
CP0181744
|
(4aR,11R,11aS)-11-methyl-2-[3-(oxan-4-yl)propyl]-9-(trifluoromethyl)-1,3,4,4a,5,6,11,11a-octahydropyrido[4,3-b]carbazole
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|
C25H33F3N2O
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0252776
|
(4aR,11R,11aS)-11-methyl-2-[2-(oxan-4-yl)ethyl]-9-(trifluoromethyl)-1,3,4,4a,5,6,11,11a-octahydropyrido[4,3-b]carbazole
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|
C24H31F3N2O
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0209382
|
4-[2-[(4aR,11R,11aS)-11-methyl-9-(trifluoromethyl)-1,3,4,4a,5,6,11,11a-octahydropyrido[4,3-b]carbazol-2-yl]ethyl]morpholin-3-one
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|
C23H28F3N3O2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0209380
|
4-[2-[(4aR,11R,11aS)-11-methyl-9-(trifluoromethyl)-1,3,4,4a,5,6,11,11a-octahydropyrido[4,3-b]carbazol-2-yl]ethyl]morpholine
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|
C23H30F3N3O
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0484528
|
4-[2-[11-methyl-9-(trifluoromethyl)-1,3,4,4a,5,6,11,11a-octahydropyrido[4,3-b]carbazol-2-yl]ethyl]morpholine
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|
C23H30F3N3O
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0204506
|
(4aR,11R,11aS)-11-methyl-2-[4-(oxan-4-yl)butyl]-9-(trifluoromethyl)-1,3,4,4a,5,6,11,11a-octahydropyrido[4,3-b]carbazole
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|
C26H35F3N2O
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0513348
|
8,9-dichloro-2,11-dimethyl-1,3,4,4a,5,6,11,11a-octahydropyrido[4,3-b]carbazole
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|
C17H20Cl2N2
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0167901
|
(4aR,11R,11aS)-11-methyl-2-(2-piperidin-1-ylethyl)-9-(trifluoromethyl)-1,3,4,4a,5,6,11,11a-octahydropyrido[4,3-b]carbazole
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|
C24H32F3N3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0439967
|
9-chloro-2,11-dimethyl-1,3,4,4a,5,6,11,11a-octahydropyrido[4,3-b]carbazole
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|
C17H21ClN2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0452068
|
2,11-dimethyl-9-(trifluoromethyl)-1,3,4,4a,5,6,11,11a-octahydropyrido[4,3-b]carbazole
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|
C18H21F3N2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0522151
|
11-methyl-2-(2-phenylethyl)-9-(trifluoromethyl)-1,3,4,4a,5,6,11,11a-octahydropyrido[4,3-b]carbazole
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|
C25H27F3N2
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0523748
|
11-methyl-2-(oxan-2-ylmethyl)-9-(trifluoromethyl)-1,3,4,4a,5,6,11,11a-octahydropyrido[4,3-b]carbazole
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|
C23H29F3N2O
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0439968
|
2,9,11-trimethyl-1,3,4,4a,5,6,11,11a-octahydropyrido[4,3-b]carbazole
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|
C18H24N2
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0475217
|
2,11-dimethyl-8-(trifluoromethyl)-1,3,4,4a,5,6,11,11a-octahydropyrido[4,3-b]carbazole
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|
C18H21F3N2
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0439969
|
9-methoxy-2,11-dimethyl-1,3,4,4a,5,6,11,11a-octahydropyrido[4,3-b]carbazole
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|
C18H24N2O
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0456560
|
2-benzyl-11-methyl-9-(trifluoromethyl)-1,3,4,4a,5,6,11,11a-octahydropyrido[4,3-b]carbazole
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|
C24H25F3N2
|
1
|
| 1 |
IC50 = 580 nM
|
|
|
|
CP0391658
|
10-chloro-2,11-dimethyl-1,3,4,4a,5,6,11,11a-octahydropyrido[4,3-b]carbazole
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|
C17H21ClN2
|
1
|
| 1 |
IC50 = 700 nM
|
|
|
|
CP0167900
|
4-[2-[(4aS,11S,11aR)-11-methyl-9-(trifluoromethyl)-1,3,4,4a,5,6,11,11a-octahydropyrido[4,3-b]carbazol-2-yl]ethyl]morpholine
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|
C23H30F3N3O
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0461420
|
7-chloro-2,11-dimethyl-1,3,4,4a,5,6,11,11a-octahydropyrido[4,3-b]carbazole
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|
C17H21ClN2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0523747
|
2,11-dimethyl-1,3,4,4a,5,6,11,11a-octahydropyrido[4,3-b]carbazole
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|
C17H22N2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0456559
|
[(2,11-dimethyl-1,3,4,4a,5,6,11,11a-octahydropyrido[4,3-b]carbazol-9-yl)amino]methanesulfonamide
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|
C18H26N4O2S
|
1
|
| 1 |
IC50 = 3300 nM
|
|
|
|
CP0461421
|
[11-methyl-9-(trifluoromethyl)-1,3,4,4a,5,6,11,11a-octahydropyrido[4,3-b]carbazol-2-yl]-phenylmethanone
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|
C24H23F3N2O
|
1
|
| 1 |
IC50 > 20000 nM
|
|
|
|
CP0475218
|
[11-methyl-9-(trifluoromethyl)-1,3,4,4a,5,6,11,11a-octahydropyrido[4,3-b]carbazol-2-yl]-(oxolan-3-yl)methanone
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|
C22H25F3N2O2
|
1
|
| 1 |
IC50 > 20000 nM
|
|
|
