Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[3-(4-cyclopropanecarbonylphenoxy)propyl]-1H-imidazole
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 PubChem ID
CID: 6422124
SID: 57304380
Canonical SMILES
O=C(C1CC1)c1ccc(OCCCc2cnc[nH]2)cc1
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Compound Formula C16H18N2O2
Compound Structure
Protein Name
 Protein Info 
Histamine H3 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Histamine receptor
Uniprot ID
Q9Y5N1
Gene Name
HRH3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000049 C6
 Cell Line Info 
Rattus norvegicus (Rat)  1
1
Ki = 63.1 nM
   TI
   LI
   LO
   TS
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
Ki = 46 nM
   TI
   LI
   LO
   TS
2
Ki = 94 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
Ki = 46 nM
   TI
   LI
   LO
   TS
2
Ki = 63.1 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 48.9 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
Ki = 46 nM
   TI
   LI
   LO
   TS
2
Ki = 224 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 46 nM
2 Ki = 63 nM