Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(+/-)-2,3-bis(4-hydroxyphenyl)propanenitrile
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 PubChem ID
CID: 102614
SID: 15366572
Canonical SMILES
Oc1ccc(CC(C#N)c2ccc(O)cc2)cc1
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Compound Formula C15H13NO2
Compound Structure
Protein Name
 Protein Info 
Estrogen receptor beta
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group A
>
Nuclear hormone receptor subfamily 3 group A member 2
Uniprot ID
Q92731
Gene Name
ESR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000209 HEC-1
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 0.85 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 0.82 nM
   TI
   LI
   LO
   TS
CL000111 MDA-MB-231
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 20 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 1.9 nM
2 EC50 = 6 nM