Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[5-(cyclopropylmethyl)-3-[4-fluoro-3-[3-(oxetan-3-yl)but-1-ynyl]phenyl]-4-[(3-fluoro-4-sulfamoylphenyl)methyl]pyrazol-1-yl]-1,3-thiazole-4-carboxylic acid
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Canonical SMILES
CC(C#Cc1cc(ccc1F)-c1nn(c(CC2CC2)c1Cc1ccc(c(F)c1)S(N)(=O)=O)-c1nc(cs1)C(O)=O)C1COC1
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Compound Formula C31H28F2N4O5S2
Compound Structure
Protein Name
 Protein Info 
L-lactate dehydrogenase A chain
Protein Classification
Enzyme
Uniprot ID
P00338
Gene Name
LDHA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000569 A-673
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1052 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 84 nM
   TI
   LI
   LO
   TS
CL000207 MIA PaCa-2
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 898 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 10 nM