Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[3-[3-(3-cyclopentylprop-1-ynyl)-4-fluorophenyl]-5-(cyclopropylmethyl)-4-[(3-fluoro-4-sulfamoylphenyl)methyl]pyrazol-1-yl]-1,3-thiazole-4-carboxylic acid
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Canonical SMILES
NS(=O)(=O)c1ccc(Cc2c(CC3CC3)n(nc2-c2ccc(F)c(c2)C#CCC2CCCC2)-c2nc(cs2)C(O)=O)cc1F
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Compound Formula C32H30F2N4O4S2
Compound Structure
Protein Name
 Protein Info 
L-lactate dehydrogenase A chain
Protein Classification
Enzyme
Uniprot ID
P00338
Gene Name
LDHA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000569 A-673
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 487 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 178 nM
   TI
   LI
   LO
   TS
CL000207 MIA PaCa-2
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 424 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 202 nM
2 Kd = 0.1235 nM