Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[5-(cyclopropylmethyl)-3-[4-fluoro-3-[2-(5-methylthiophen-2-yl)ethynyl]phenyl]-4-[(3-fluoro-4-sulfamoylphenyl)methyl]pyrazol-1-yl]-1,3-thiazole-4-carboxylic acid
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 PubChem ID
CID: 139465358
Canonical SMILES
Cc1ccc(s1)C#Cc1cc(ccc1F)-c1nn(c(CC2CC2)c1Cc1ccc(c(F)c1)S(N)(=O)=O)-c1nc(cs1)C(O)=O
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Compound Formula C31H24F2N4O4S3
Compound Structure
Protein Name
 Protein Info 
L-lactate dehydrogenase A chain
Protein Classification
Enzyme
Uniprot ID
P00338
Gene Name
LDHA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000569 A-673
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 873 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 106 nM
   TI
   LI
   LO
   TS
CL000207 MIA PaCa-2
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 403 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 57 nM
2 Kd = 0.0667 nM