Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(3-([1,1'-biphenyl]- difluorocyclopropyl)- 4-(4- sulfamoylbenzyl)- 1H-pyrazol-1- yl)thiazole-4- carboxylic acid
    Show/Hide
 PubChem ID
CID: 121461853
Canonical SMILES
NS(=O)(=O)c1ccc(Cc2c(nn(-c3nc(cs3)C(O)=O)c2C2CC2(F)F)-c2cccc(c2)-c2ccccc2)cc1
    Show/Hide
Compound Formula C29H22F2N4O4S2
Compound Structure
Protein Name
 Protein Info 
L-lactate dehydrogenase A chain
Protein Classification
Enzyme
Uniprot ID
P00338
Gene Name
LDHA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000569 A-673
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1861 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 2529 nM
   TI
   LI
   LO
   TS
CL000207 MIA PaCa-2
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 4760 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 36 nM