Brief Information of the Compound and Protein
Compound Name
 Compound Info 
Ft-2102
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 PubChem ID
CID: 118955396
Canonical SMILES
C[C@H](Nc1ccc(C#N)n(C)c1=O)c1cc2cc(Cl)ccc2[nH]c1=O
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Compound Formula C18H15ClN4O2
Compound Structure
Protein Name
 Protein Info 
Isocitrate dehydrogenase [NADP] cytoplasmic
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
O75874
Gene Name
IDH1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000067 HCT 116
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 21 nM
   TI
   LI
   LO
   TS
2
IC50 = 94 nM
   TI
   LI
   LO
   TS
CL000102 U-87MG ATCC
 Cell Line Info 
Homo sapiens (Human)  4
1
IC50 = 6 nM
   TI
   LI
   LO
   TS
2
IC50 = 9 nM
   TI
   LI
   LO
   TS
3
IC50 = 39 nM
   TI
   LI
   LO
   TS
4
IC50 = 42 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 21.2 nM
2 IC50 = 114 nM
3 IC50 = 22400 nM