Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-methyl-4-[(10S,14R)-14-methyl-6-(2-methylsulfonylpropan-2-yl)-8,12-dioxa-1,3,5-triazatricyclo[8.4.0.02,7]tetradeca-2,4,6-trien-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-amine
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 PubChem ID
CID: 132178541
Canonical SMILES
CNc1cnc2[nH]ccc2c1-c1nc2N3[C@H](C)COC[C@H]3COc2c(n1)C(C)(C)S(C)(=O)=O
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Compound Formula C22H28N6O4S
Compound Structure
Protein Name
 Protein Info 
Serine/threonine-protein kinase ATR
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Atypical protein kinase group
>
Atypical protein kinase PIKK family
Uniprot ID
Q13535
Gene Name
ATR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000007 HT-29
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 < 10 nM
   TI
   LI
   LO
   TS
CL000043 U2OS
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 10 nM
   TI
   LI
   LO
   TS