Brief Information of the Compound and Protein
Compound Name
5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)-1,3-thiazol-2-amine
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PubChem ID
CID: 46836872
SID: 99220043
Canonical SMILES
Cc1sc(Nc2nccc(C)n2)nc1-c1cn[nH]c1
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Compound Formula C12H12N6S
Compound Structure
Protein Name
Metabotropic glutamate receptor 4
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
Q14833
Gene Name
GRM4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 = 52 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 4 nM