Brief Information of the Compound and Protein
Compound Name
N-[4-[[methyl(oxan-4-yl)amino]methyl]phenyl]-7-(4-methylphenyl)-2-(2-methylpropyl)-1-oxo-3H-2-benzazepine-4-carboxamide
    Show/Hide
PubChem ID
CID: 132572938
Canonical SMILES
CC(C)CN1CC(=Cc2cc(ccc2C1=O)-c1ccc(C)cc1)C(=O)Nc1ccc(CN(C)C2CCOCC2)cc1
    Show/Hide
Compound Formula C35H41N3O3
Compound Structure
Protein Name
C-C chemokine receptor type 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Chemokine receptor
>
CC chemokine receptor
Uniprot ID
P41597
Gene Name
CCR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000064 Chem-1 Rattus norvegicus (Rat)  1
1
IC50 = 140 nM
   TI
   LI
   LO
   TS
CL000043 U2OS Homo sapiens (Human)  1
1
IC50 = 387 nM
   TI
   LI
   LO
   TS