Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl)methyl)-(1,1'-biphenyl)-2-carboxylic acid
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 PubChem ID
CID: 65999
SID: 14860450
Canonical SMILES
CCCc1nc2c(C)cc(cc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O)-c1nc2ccccc2n1C
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Compound Formula C33H30N4O2
Compound Structure
Protein Name
 Protein Info 
Peroxisome proliferator-activated receptor gamma
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 1
>
Nuclear hormone receptor subfamily 1 group C
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Nuclear hormone receptor subfamily 1 group C member 3
Uniprot ID
P37231
Gene Name
PPARG
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 3400 nM
   TI
   LI
   LO
   TS
CL000053 COS-7
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  3
1
EC50 = 4280 nM
   TI
   LI
   LO
   TS
2
EC50 = 4710 nM
   TI
   LI
   LO
   TS
3
EC50 = 4970 nM
   TI
   LI
   LO
   TS
CL000044 CV-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
EC50 = 2020 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 700 nM
2 EC50 = 1520 nM