Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[5-methyl-1-[3-(prop-2-enoylamino)phenyl]benzimidazol-2-yl]-3-(trifluoromethyl)benzamide
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 PubChem ID
CID: 72699656
Canonical SMILES
Cc1ccc2n(c(NC(=O)c3cccc(c3)C(F)(F)F)nc2c1)-c1cccc(NC(=O)C=C)c1
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Compound Formula C25H19F3N4O2
Compound Structure
Protein Name
 Protein Info 
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000150 HaCaT
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CL000157 NCI-H1975
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 134.8 nM
   TI
   LI
   LO
   TS
CL000324 NCI-H3255
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1041 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 4 nM
   TI
   LI
   LO
   TS
2
IC50 > 50000 nM
   TI
   LI
   LO
   TS