Brief Information of the Compound and Protein
Compound Name
pyridylpurine aminoisoquinoline, 1
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PubChem ID
CID: 44223999
SID: 92728611
Canonical SMILES
Cc1ccc2c(Nc3ccc(Cl)cc3)nccc2c1Nc1ncccc1-c1ncnc2nc[nH]c12
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Compound Formula C26H19ClN8
Compound Structure
Protein Name
Serine/threonine-protein kinase B-raf
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase RAF family
Uniprot ID
P15056
Gene Name
BRAF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000045 A-375 Homo sapiens (Human)  1
1
IC50 = 2 nM
   TI
   LI
   LO
   TS
CL000207 MIA PaCa-2 Homo sapiens (Human)  1
1
EC50 = 22 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2 nM
2 Ki = 1 nM