Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl]benzoic acid
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 PubChem ID
CID: 82146
SID: 87550948
Canonical SMILES
Cc1cc2c(cc1C(=C)c1ccc(cc1)C(O)=O)C(C)(C)CCC2(C)C
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Compound Formula C24H28O2
Compound Structure
Protein Name
 Protein Info 
Retinoic acid receptor RXR-alpha
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 2
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Nuclear hormone receptor subfamily 2 group B
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Nuclear hormone receptor subfamily 2 group B member 1
Uniprot ID
P19793
Gene Name
RXRA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000109 COS-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
EC50 = 20 nM
   TI
   LI
   LO
   TS
CL000044 CV-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  3
1
EC50 = 28 nM
   TI
   LI
   LO
   TS
2
EC50 = 33 nM
   TI
   LI
   LO
   TS
3
EC50 = 118 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 40 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 33 nM
2 EC50 = 42 nM
3 Kd = 14 nM
4 Kd = 26 nM
5 Kd = 36 nM
6 Kd = 210 nM
7 Kd = 1590 nM
8 Kd = 1890 nM
9 Ki = 14 nM
10 Ki = 16 nM
11 Ki = 36 nM
12 Ki = 150 nM
13 Ki = 379 nM