Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9169260, 18
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 PubChem ID
CID: 68328146
Canonical SMILES
Cc1ccc(cc1)-n1nc(cc1NC(=O)c1cnn2cccnc12)C1CCN(CC1)S(C)(=O)=O
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Compound Formula C23H25N7O3S
Compound Structure
Protein Name
 Protein Info 
Interleukin-1 receptor-associated kinase 4
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase IRAK family
Uniprot ID
Q9NWZ3
Gene Name
IRAK4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 67 nM
   TI
   LI
   LO
   TS
CL000864 THP1-Xblue
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 2400 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 < 100 nM