Bioactivity Information

Brief Information of the Compound and Protein

Compound Name

Compound Info

3-Hydroxy-2-phenyl-propionic acid 9-methyl-3-oxa-9-aza-tricyclo[3.3.1.0*2,4*]non-7-yl ester

Show/Hide

Canonical SMILES	C[N+]1(C)[C@H]2C[C@@H](C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)c1ccccc1 Show/Hide
Compound Formula	C18H24NO4+

Compound Structure

Protein Name

Protein Info

Muscarinic acetylcholine receptor M2

Protein Classification

Membrane receptor

Family A G protein-coupled receptor

Small molecule receptor (family A GPCR)

Monoamine receptor

Acetylcholine receptor

Uniprot ID

P08172

Gene Name

CHRM2

Table of Molecular Bioactivities Related to the Compound and Protein

Cell-based Assay

Cell Line ID	Cell Line Name	Cell Line Organism
CL000011	CHO Cell Line Info	Cricetulus griseus (Chinese hamster)	2
1	IC50 = 4.3 nM	TI LI LO TS
2	Ki = 0.1778 nM	TI LI LO TS
CL000845	CHO-K9 Cell Line Info	Cricetulus griseus (Chinese hamster)	4
1	IC50 = 398.11 nM	TI LI LO TS
2	IC50 = 436.52 nM	TI LI LO TS
3	IC50 = 501.19 nM	TI LI LO TS
4	Ki = 0.0631 nM	TI LI LO TS
CL000386	Flp-In-CHO Cell Line Info	Cricetulus griseus (Chinese hamster)	5
1	Ki = 0.3311 nM	TI LI LO TS
2	Ki = 0.4266 nM	TI LI LO TS
3	Ki = 0.4365 nM	TI LI LO TS
4	Ki = 0.7244 nM	TI LI LO TS
5	Ki = 10.47 nM	TI LI LO TS