Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[4-(4-quinazolin-4-ylpiperazin-1-yl)butyl]imidazo[1,2-a]pyridine-2-carboxamide
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 PubChem ID
CID: 117869686
Canonical SMILES
O=C(NCCCCN1CCN(CC1)c1ncnc2ccccc12)c1cn2ccccc2n1
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Compound Formula C24H27N7O
Compound Structure
Protein Name
 Protein Info 
D(3) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P35462
Gene Name
DRD3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 940 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 253 nM
   TI
   LI
   LO
   TS
CL000043 U2OS
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 409 nM
   TI
   LI
   LO
   TS