Brief Information of the Compound and Protein
Compound Name
N-(4-chlorophenyl)-5-ethyl-N-methyl-3-phenyltriazole-4-carboxamide
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PubChem ID
CID: 46232736
SID: 99218957
Canonical SMILES
CCc1nnn(c1C(=O)N(C)c1ccc(Cl)cc1)-c1ccccc1
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Compound Formula C18H17ClN4O
Compound Structure
Protein Name
G-protein coupled bile acid receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Steroid-like ligand receptor
Uniprot ID
Q8TDU6
Gene Name
GPBAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 53 nM
   TI
   LI
   LO
   TS
2
EC50 = 1423 nM
   TI
   LI
   LO
   TS
CL000386 Flp-In-CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 47 nM
   TI
   LI
   LO
   TS
2
EC50 = 1420 nM
   TI
   LI
   LO
   TS
CL000043 U2OS Homo sapiens (Human)  1
1
EC50 = 12.59 nM
   TI
   LI
   LO
   TS