Brief Information of the Compound and Protein
Compound Name
(R)-4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl)benzonitrile
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PubChem ID
CID: 9815923
SID: 16338122
Canonical SMILES
N#Cc1ccc(cc1)[C@H]1CCCc2cncn12
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Compound Formula C14H13N3
Compound Structure
Protein Name
Cytochrome P450 11B2, mitochondrial
Protein Classification
Enzyme
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Cytochrome P450
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Cytochrome P450 family 11
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Cytochrome P450 family 11B
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Cytochrome P450 11B2
Uniprot ID
P19099
Gene Name
CYP11B2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000050 HEK293-A Homo sapiens (Human)  1
1
IC50 = 4 nM
   TI
   LI
   LO
   TS
CL000263 NCI-H295R Homo sapiens (Human)  1
1
IC50 = 30 nM
   TI
   LI
   LO
   TS
CL000191 V79 Cricetulus griseus (Chinese hamster)  1
1
IC50 = 6 nM
   TI
   LI
   LO
   TS
CL000170 V79MZ Cricetulus griseus (Chinese hamster)  1
1
IC50 = 6 nM
   TI
   LI
   LO
   TS