Brief Information of the Compound and Protein
Compound Name
 Compound Info 
SID99309109
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 PubChem ID
CID: 9581011
Canonical SMILES
COC(=O)c1cnn(-c2ccc(F)cc2F)c1/C=N/NC(=S)NC(C)(C)C
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Compound Formula C17H19F2N5O2S
Compound Structure
Protein Name
 Protein Info 
G-protein coupled receptor 35
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Carboxylic acid receptor
>
Kynurenic acid receptor
Uniprot ID
Q9HC97
Gene Name
GPR35
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 574 nM
   TI
   LI
   LO
   TS
2
Ki = 42.2 nM
   TI
   LI
   LO
   TS
CL000007 HT-29
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 10400 nM
   TI
   LI
   LO
   TS
CL000043 U2OS
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 200 nM
   TI
   LI
   LO
   TS
2
IC50 = 1390 nM
   TI
   LI
   LO
   TS