Brief Information of the Compound and Protein
Compound Name
 Compound Info 
CAS_4394-00-7
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 PubChem ID
CID: 4488
SID: 14750946
Canonical SMILES
OC(=O)c1cccnc1Nc1cccc(c1)C(F)(F)F
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Compound Formula C13H9F3N2O2
Compound Structure
Protein Name
 Protein Info 
G-protein coupled receptor 35
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Carboxylic acid receptor
>
Kynurenic acid receptor
Uniprot ID
Q9HC97
Gene Name
GPR35
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 30800 nM
   TI
   LI
   LO
   TS
2
Ki = 3610 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 15000 nM
   TI
   LI
   LO
   TS
CL000007 HT-29
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 1150 nM
   TI
   LI
   LO
   TS
2
IC50 = 1280 nM
   TI
   LI
   LO
   TS
CL000043 U2OS
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 40200 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 1110 nM