Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol;hydrate;hydrochloride
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 PubChem ID
CID: 6005
SID: 14823961
Canonical SMILES
CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31
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Compound Formula C17H17NO2
Compound Structure
Protein Name
 Protein Info 
D(1A) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P21728
Gene Name
DRD1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 52 nM
   TI
   LI
   LO
   TS
CL000053 COS-7
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
Kd = 680 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  4
1
EC50 = 25.7 nM
   TI
   LI
   LO
   TS
2
Ki = 290 nM
   TI
   LI
   LO
   TS
3
Ki = 492 nM
   TI
   LI
   LO
   TS
4
Ki = 660 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 4.6 nM
2 Ki = 650 nM