Brief Information of the Compound and Protein
Compound Name
 Compound Info 
Adamantane-1-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-4-guanidino-butyl]-amide
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 PubChem ID
CID: 53320361
Canonical SMILES
NC(N)=NCCC[C@H](NC(=O)C12CC3CC(CC(C3)C1)C2)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
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Compound Formula C26H38N6O3
Compound Structure
Protein Name
 Protein Info 
Neuropeptide FF receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
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RF amide receptor
Uniprot ID
Q9GZQ6
Gene Name
NPFFR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  4
1
EC50 = 4700 nM
   TI
   LI
   LO
   TS
2
Ki = 14 nM
   TI
   LI
   LO
   TS
3
Ki = 22 nM
   TI
   LI
   LO
   TS
4
Ki = 58 nM
   TI
   LI
   LO
   TS
CL000109 COS-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
EC50 = 71 nM
   TI
   LI
   LO
   TS