Bioactivity Information

Brief Information of the Compound and Protein

Compound Name

Compound Info

L-Val-L-Pro-L-Asn-L-Leu-L-Pro-L-Gln-L-Arg-L-Phe-NH2

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PubChem ID

CID: 71451611

Canonical SMILES	CC(C)C[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O Show/Hide
Compound Formula	C45H72N14O10

Compound Structure

Protein Name

Protein Info

Neuropeptide FF receptor 1

Protein Classification

Membrane receptor

Family A G protein-coupled receptor

Peptide receptor (family A GPCR)

Short peptide receptor (family A GPCR)

RF amide receptor

Uniprot ID

Q9GZQ6

Gene Name

NPFFR1

Table of Molecular Bioactivities Related to the Compound and Protein

Cell-based Assay

Cell Line ID	Cell Line Name	Cell Line Organism
CL000011	CHO Cell Line Info	Cricetulus griseus (Chinese hamster)	3
1	Ki = 0.01 nM	TI LI LO TS
2	Ki = 0.59 nM	TI LI LO TS
3	Ki = 3.66 nM	TI LI LO TS
CL000109	COS-1 Cell Line Info	Chlorocebus aethiops (Green monkey)	1
1	EC50 = 1.7 nM	TI LI LO TS
CL000006	HEK293 Cell Line Info	Homo sapiens (Human)	3
1	EC50 = 30 nM	TI LI LO TS
2	EC50 = 50 nM	TI LI LO TS
3	Ki = 1.3 nM	TI LI LO TS