Brief Information of the Compound and Protein
Compound Name
N-(6-amino-5-bromopyridin-3-yl)-2,6-difluoro-3-(propylsulfonylamino)benzamide
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PubChem ID
CID: 44217243
SID: 85231834
Canonical SMILES
CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc(N)c(Br)c2)c1F
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Compound Formula C15H15BrF2N4O3S
Compound Structure
Protein Name
Serine/threonine-protein kinase B-raf
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase RAF family
Uniprot ID
P15056
Gene Name
BRAF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000045 A-375 Homo sapiens (Human)  1
1
IC50 = 1200 nM
   TI
   LI
   LO
   TS
CL000212 Malme-3M Homo sapiens (Human)  1
1
IC50 = 310 nM
   TI
   LI
   LO
   TS