Brief Information of the Compound and Protein
| Compound Name |
2-(difluoromethyl)-1-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)-1H-benzimidazole
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PubChem ID | |||||
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Compound Structure |
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| Protein Name |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
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Protein Classification |
Enzyme
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Transferase
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| Uniprot ID | Gene Name | PIK3CA |
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Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Biochemical Assays
| 1 | EC50 = 50 nM | ||
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| 2 | IC50 = 5 nM | ||
| 3 | IC50 = 6 nM | ||
| 4 | IC50 = 8.9 nM | ||
| 5 | IC50 = 12 nM | ||
| 6 | IC50 = 16 nM | ||
| 7 | IC50 = 25 nM | ||
| 8 | IC50 = 26 nM | ||