Brief Information of the Compound and Protein
| Compound Name |
2-cyclohexyl-6-methoxy-N-(1-propan-2-ylpiperidin-4-yl)-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine
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PubChem ID | |||||
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Compound Structure |
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| Protein Name |
Histone-lysine N-methyltransferase EHMT2
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Protein Classification |
Epigenetic regulator
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Protein methyltransferase
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| Uniprot ID | Gene Name | EHMT2 |
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Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Biochemical Assays
| 1 | IC50 < 2.5 nM | ||
|---|---|---|---|
| 2 | IC50 = 2.5 nM | ||
| 3 | IC50 = 12 nM | ||
| 4 | IC50 < 15 nM | ||
| 5 | IC50 = 15 nM | ||
| 6 | IC50 = 25 nM | ||
| 7 | IC50 = 30 nM | ||
| 8 | IC50 = 55 nM | ||
| 9 | IC50 = 610 nM | ||
| 10 | Ki = 3.7 nM | ||
| 11 | Ki = 18 nM | ||