Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-(1-cyclohexylpiperidin-4-yl)-6-methoxy-7-(3-piperidin-1-ylpropoxy)-2-(4-propan-2-yl-1,4-diazepan-1-yl)quinazolin-4-amine
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 PubChem ID
CID: 53315882
SID: 126518093
Canonical SMILES
COc1cc2c(NC3CCN(CC3)C3CCCCC3)nc(nc2cc1OCCCN1CCCCC1)N1CCCN(CC1)C(C)C
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Compound Formula C36H59N7O2
Compound Structure
Protein Name
 Protein Info 
Histone-lysine N-methyltransferase EHMT2
Protein Classification
Epigenetic regulator
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Protein methyltransferase
Uniprot ID
Q96KQ7
Gene Name
EHMT2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000237 22Rv1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 14 nM
   TI
   LI
   LO
   TS
CL000067 HCT 116
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 68 nM
   TI
   LI
   LO
   TS
2
IC50 = 86 nM
   TI
   LI
   LO
   TS
CL000411 IMR-90
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 10 nM
   TI
   LI
   LO
   TS
CL000083 MCF-7
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 10 nM
   TI
   LI
   LO
   TS
CL000111 MDA-MB-231
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 26 nM
   TI
   LI
   LO
   TS
CL000048 PC-3
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 12 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 6 nM