Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-(3-bromophenyl)-6,7-dimethoxyquinazolin-4-amine
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 PubChem ID
CID: 4705
SID: 14852461
Canonical SMILES
COc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OC
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Compound Formula C16H14BrN3O2
Compound Structure
Protein Name
 Protein Info 
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000052 A-431
 Cell Line Info 
Homo sapiens (Human)  6
1
IC50 = 0.029 nM
   TI
   LI
   LO
   TS
2
IC50 = 4 nM
   TI
   LI
   LO
   TS
3
IC50 < 15 nM
   TI
   LI
   LO
   TS
4
IC50 = 30 nM
   TI
   LI
   LO
   TS
5
IC50 = 200 nM
   TI
   LI
   LO
   TS
6
IC50 = 230 nM
   TI
   LI
   LO
   TS
CL000254 DiFi
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 70.79 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.029 nM
2 IC50 = 0.095 nM
3 IC50 = 2.6 nM
4 IC50 = 4 nM
5 IC50 = 5.3 nM
6 IC50 = 6 nM
7 IC50 = 25 nM
8 IC50 = 28 nM
9 IC50 = 63 nM
10 IC50 = 70 nM
11 IC50 = 200 nM
12 IC50 = 230 nM
13 IC50 > 100 nM