Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US10383835, Compound 1153
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 PubChem ID
CID: 12000797
Canonical SMILES
CC(=O)N1CCC(CC1)NC(=O)NC12CC3CC(CC(C3)C1)C2
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Compound Formula C18H29N3O2
Compound Structure
Protein Name
 Protein Info 
Bifunctional epoxide hydrolase 2
Protein Classification
Enzyme
>
Protease
>
Serine protease
>
Serine protease SC clan
>
Serine protease S33 family
Uniprot ID
P34913
Gene Name
EPHX2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000749 HUVEC-C
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 57 nM
   TI
   LI
   LO
   TS
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 8 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 7 nM
2 IC50 = 8 nM
3 IC50 = 13.8 nM
4 IC50 = 15 nM
5 Ki = 19.5 nM