Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(3R,6R,7S,8E,10S,11S,12E,14E,16R,18R,19R,20R,21S)-7-[(4-cycloheptylpiperazin-1-yl)carbonyl]oxy-3,6,16,21-tetrahydroxy-6,10,12,16,20-pentamethyl-18,19-epoyxtrichosa-8,12,14-trien-11-olide
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 PubChem ID
CID: 52943181
Canonical SMILES
CC[C@H](O)[C@@H](C)[C@H]1O[C@@H]1C[C@@](C)(O)/C=C/C=C(\C)[C@H]1OC(=O)C[C@H](O)CC[C@@](C)(O)[C@@H](OC(=O)N2CCN(C3CCCCCC3)CC2)CC[C@@H]1C
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Compound Formula C40H68N2O9
Compound Structure
Protein Name
 Protein Info 
Splicing factor 3B subunit 3
Protein Classification
Other nuclear protein
Uniprot ID
Q15393
Gene Name
SF3B3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000118 U-251MG
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 3.6 nM
   TI
   LI
   LO
   TS
CL000202 WiDr
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 3.2 nM
   TI
   LI
   LO
   TS